Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AKT1_HUMAN
Description:v-akt murine thymoma viral oncogene homolog 1 [Source:HGNC Symbol;Acc:391]
Location:chr14 q32.33
Node attribute:substrate; kinase; cleavage(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y315CGTPEyLAPEVPkinasePhosphoSitePlus
T308GATMKtFCGTPPkinasePhosphoSitePlus
S475PQFSYsASGTAPkinase_CPhosphoSitePlus
S473HFPQFsYSASGPDK1HPRD; RegPhos
Y437ETDTRyFDEEFPkinase_CPhosphoSitePlus
Y474FPQFSySASGTPkinase_CPhosphoSitePlus
S473HFPQFsYSASGPDHK1RegPhos
S473HFPQFsYSASGPkinase_CPhosphoSitePlus
Y326LEDNDyGRAVDSRCHPRD; RegPhos
S122EMDFRsGSPSDPhosphoSitePlus; HPRD; phosphoELM
S129SPSDNsGAEEMCK2_alphaphosphoELM
T305IKDGAtMKTFCPkinasePhosphoSitePlus
T308GATMKtFCGTPCaMKK1RegPhos
T479YSASGtA____PhosphoSitePlus
T312KTFCGtPEYLAPkinasePhosphoSitePlus
T308GATMKtFCGTPPDK-1phosphoELM
Y315CGTPEyLAPEVSRCHPRD; RegPhos
S129SPSDNsGAEEMCK2a1(CK2 alphaRegPhos
T92TFHVEtPEEREPHPhosphoSitePlus
S473HFPQFsYSASGPDPK1HPRD
T65CQLMKtERPRPPHPhosphoSitePlus
S124DFRSGsPSDNSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
Y474FPQFSySASGTRegPhos
Y326LEDNDyGRAVDPkinasePhosphoSitePlus
Y176ATGRYyAMKILPkinasePhosphoSitePlus
T87TVIERtFHVETPHPhosphoSitePlus
S477FSYSAsGTA__Pkinase_CPhosphoSitePlus
T72RPRPNtFIIRCPHPhosphoSitePlus
S126RSGSPsDNSGAPhosphoSitePlus; HPRD; phosphoELM; RegPhos
Y417VWQHVyEKKLSPhosphoSitePlus
S473HFPQFsYSASGRHEBL1HPRD
T450QMITItPPDQDPkinase_CPhosphoSitePlus
T308GATMKtFCGTPPDK1HPRD; RegPhos
S129SPSDNsGAEEMPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S473HFPQFsYSASGHPRD; RegPhos
T308GATMKtFCGTPPDPK1HPRD
Y474FPQFSySASGHPRD; phosphoELM
T450QMITItPPDQDHPRD; phosphoELM; RegPhos
T435TSETDtRYFDEPkinase_CPhosphoSitePlus
T308GATMKtFCGTPHPRD; RegPhos
S473HFPQFsYSASGPDK-1phosphoELM
S473HFPQFsYSASGILKHPRD; phosphoELM; RegPhos
T308GATMKtFCGTPCAMKK1HPRD
T146PKHRVtMNEFEPhosphoSitePlus
T308GATMKtFCGTPPDHK1RegPhos
S246RERVFsEDRARPkinasePhosphoSitePlus

Dephosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S473RPHFPQFsYSASGTAPPP2CAHPRD
T308KDGATMKtFCGTPEYPPP2CAHPRD

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000384293E17KOMIMColorectal Cancer17611497
ENSP00000385326F35LDing2008Lung Cancer18948947
ENSP00000384293E17KOMIMOvarian Cancer17611497
ENSP00000270202E17KOMIMColorectal Cancer17611497
ENSP00000384293P374TBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000385326E17KBIOMART, HPI, OMIMBreast Cancer21930507, 21930502, 19713527 17611497 21793738 21124076 21932773 21793738 21617917 20980808 20493625 20407443 20440266 20101210 20022634 19898424 19853286 19802009 19744127 19736514 19491896 19461960
ENSP00000385326E17KDing2008Lung Cancer18948947
ENSP00000385326E17KOMIMColorectal Cancer17611497
ENSP00000270202L52RBIOMARTBreast Cancer21930507, 21930502
ENSP00000385326L52RBIOMARTBreast Cancer21930507, 21930502
ENSP00000384293E17KDing2008Lung Cancer18948947
ENSP00000385326E17KOMIMOvarian Cancer17611497
ENSP00000270202E17KOMIMOvarian Cancer17611497
ENSP00000385326Q79KBIOMARTBreast Cancer21930507, 21930502
ENSP00000384293F35LDing2008Lung Cancer18948947
ENSP00000384293L52RBIOMARTBreast Cancer21930507, 21930502
ENSP00000270202F35LDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502
ENSP00000270202Q79KBIOMARTBreast Cancer21930507, 21930502
ENSP00000384293E17KBIOMART, HPI, OMIMBreast Cancer21930507, 21930502, 19713527 17611497 21793738 21124076 21932773 21793738 21617917 20980808 20493625 20407443 20440266 20101210 20022634 19898424 19853286 19802009 19744127 19736514 19491896 19461960
ENSP00000270202E17KOMIM, HPIBreast Cancer17611497, 19713527 17611497 21793738 21124076 21932773 21793738 21617917 20980808 20493625 20407443 20440266 20101210 20022634 19898424 19853286 19802009 19744127 19736514 19491896 19461960
ENSP00000384293Q79KBIOMARTBreast Cancer21930507, 21930502
ENSP00000270202E17KDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502, 19713527, 17611497, 21793738, 21124076, 21932773, 21793738, 21617917, 20980808, 20493625, 20407443, 20440266, 20101210, 20022634, 19898424, 19853286, 19802009, 19744127, 19736514, 19491896, 19461960

Differential expressed protein
AKT1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SiteMotifPeptideCancer namePubmedSource
S473Pkinase_CRPHFPQFsYSASGTArhabdomyosarcoma17848913PhosphoSitePlus
T308PkinaseKDGATMKtFCGTPEYrhabdomyosarcoma17848913PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTApancreatic cancer15467756PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTApapillary thyroid carcinoma; follicular thyroid carcinoma; anaplastic thyroid carcinoma15743786PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAhepatitis18316359PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAParkinson's disease19800394PhosphoSitePlus
Y176PkinaseEKATGRYyAMKILKKbreast cancer20333297PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAliver cancer15684384PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAmelanoma skin cancer12499277PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAovarian cancer15208673PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAbreast cancer17545609PhosphoSitePlus
T308PkinaseKDGATMKtFCGTPEYneuroblastoma17234785PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAneuroblastoma17234785PhosphoSitePlus
T308PkinaseKDGATMKtFCGTPEYovarian cancer20153512PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAurethral cancer; brain cancer; colorectal cancer22975685PhosphoSitePlus
T308PkinaseKDGATMKtFCGTPEYtype 2 diabetes20938636PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAthymic carcinoma20597130PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTAmelanoma skin cancer19996208PhosphoSitePlus
T308PkinaseKDGATMKtFCGTPEYmelanoma skin cancer19996208PhosphoSitePlus
T308PkinaseKDGATMKtFCGTPEYKaposi's sarcoma21819957PhosphoSitePlus
T308PkinaseKDGATMKtFCGTPEYtype 2 diabetes15919790PhosphoSitePlus
S473Pkinase_CRPHFPQFsYSASGTApancreatic cancer21474066PhosphoSitePlus

Direct Interaction Pair
SourceTargetRelationshipResource
AKT1_HUMANUTP18_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANRS20_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANESR1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANPTEN_HUMANkinase -> substrateRegPhos
AKT1_HUMANTHA_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSMPX_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANIRAK1_HUMANkinase -> substrateRegPhos
AKT1_HUMANMK08_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANCREB1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANKPCD_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANIKKA_HUMANkinase -> substrateHPRD; RegPhos; NetPath
AKT1_HUMANPRGC2_HUMANkinase -> substrateHPRD
AKT1_HUMANMDM4_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
AKT1_HUMAN1433Z_HUMANkinase -> substrateRegPhos
AKT1_HUMANHIRP3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSREK1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANABI2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANBAD_HUMANkinase -> substrateNetPath
AKT1_HUMANTEAD1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSYNJ2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANBRAF_HUMANkinase -> substrateRegPhos
AKT1_HUMANEZH2_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANHMOX1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANRHG07_HUMANkinase -> substrateRegPhos
AKT1_HUMANSPF45_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANCDKA1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANGSK3A_HUMANkinase -> substrateNetPath
ZAGL2_HUMANAKT1_HUMANkinase -> substrateRegPhos
AKT1_HUMANRAGE_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANFOXO1_HUMANkinase -> substrateRegPhos; NetPath
AKT1_HUMANXPA_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANGATA1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANACAP2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANMEF2C_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANGRDN_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANMTG8_HUMANkinase -> substrateRobert H Newman (2013)
PDPK2_HUMANAKT1_HUMANkinase -> substrateNetPath
AKT1_HUMANNDF1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANNUAK1_HUMANkinase -> substrateRegPhos
AKT1_HUMANPCBP3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANKPCA_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANENC2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANFGR_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANCIP4_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANPCBP2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSMAD3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANNU133_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANITB3_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANM3K8_HUMANkinase -> substrateRegPhos
AKT1_HUMANMDFI_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSTAT6_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANGAS7_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANC99L2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANCDN1A_HUMANkinase -> substrateRegPhos
PDPK1_HUMANAKT1_HUMANkinase -> substrateRegPhos; NetPath
AKT1_HUMANZHX1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSC6A4_HUMANkinase -> substrateHPRD
AKT1_HUMANGSK3B_HUMANkinase -> substrateHPRD; RegPhos; NetPath
AKT1_HUMANLC7L2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANHNRPK_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMAN4EBP1_HUMANkinase -> substrateRegPhos
SRC_HUMANAKT1_HUMANkinase -> substrateRegPhos
AKT1_HUMANSRC8_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSOX9_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANHJURP_HUMANkinase -> substrateRegPhos
AKT1_HUMANCCM2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANYAP1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANSRSF1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANM3K5_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANMED28_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANATX1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANGA45A_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANGAB2_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANIASPP_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANT2EA_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANCS021_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANFIP1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANF262_HUMANkinase -> substrateRegPhos
AKT1_HUMANYBOX1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANFOXN3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANRON_HUMANkinase -> substrateNetPath
AKT1_HUMANID2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANTF2B_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANANM1_HUMANkinase -> substrateRobert H Newman (2013)
PDK1_HUMANAKT1_HUMANkinase -> substrateRegPhos
AKT1_HUMANCDN1B_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANFOXO3_HUMANkinase -> substrateRegPhos; NetPath
AKT1_HUMANS1PR1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANTRMB_HUMANkinase -> substrateHPRD
AKT1_HUMANCHK1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANCDK9_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANMTOR_HUMANkinase -> substrateRegPhos
AKT1_HUMANPINX1_HUMANkinase -> substrateRobert H Newman (2013)
KKCC1_HUMANAKT1_HUMANkinase -> substrateHPRD
AKT1_HUMANNUCL_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANKC1G2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANBRD2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANEP300_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANPOP7_HUMANkinase -> substrateRobert H Newman (2013)
CSK21_HUMANAKT1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSLX4_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANBC11A_HUMANkinase -> substrateRobert H Newman (2013)
REBL1_HUMANAKT1_HUMANkinase -> substrateHPRD
AKT1_HUMANNOS3_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANDAXX_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANERAL1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANHD_HUMANkinase -> substrateRegPhos
AKT1_HUMANSH2B2_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANPDE3B_HUMANkinase -> substrateRegPhos
AKT1_HUMANPTN1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANNRIP2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANPHLA2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANPKHA4_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANRAF1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANMP2K4_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANSMYD2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANM3K11_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANTCAL6_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANFANCA_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANRU17_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANRAC1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANAVEN_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANWIPI3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANDNJB2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANNOC2L_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANNFAC3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANTSC2_HUMANkinase -> substrateRegPhos
AKT1_HUMANETS1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANCASP9_HUMANkinase -> substrateRegPhos
AKT1_HUMANMTA1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANTERT_HUMANkinase -> substrateRegPhos; NetPath
AKT1_HUMANTSN_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANZRAB2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANPEA15_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANXIAP_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANCBL_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANNCOA4_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANTRAT1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANBRCA1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANFR1OP_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANNR4A1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANMDM2_HUMANkinase -> substrateRegPhos
P85A_HUMANAKT1_HUMANkinase -> substrateNetPath
AKT1_HUMANSNIP1_HUMANkinase -> substrateRobert H Newman (2013)
ILK_HUMANAKT1_HUMANkinase -> substrateHPRD; RegPhos; Robert H Newman (2013)
AKT1_HUMANSCG1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANANDR_HUMANkinase -> substrateRegPhos; NetPath
AKT1_HUMANRELL2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANHCLS1_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANAKTS1_HUMANkinase -> substrateHPRD; RegPhos
AKT1_HUMANARFG2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANOTU7B_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANRXRA_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANCFLAR_HUMANkinase -> substrateNetPath
AKT1_HUMANZC11A_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANGATA2_HUMANkinase -> substrateHPRD
AKT1_HUMANTBCD4_HUMANkinase -> substrateRegPhos
AKT1_HUMANFOXO4_HUMANkinase -> substrateRegPhos
PP2AA_HUMANAKT1_HUMANphosphatase -> substrateHPRD
CASP3_HUMANAKT1_HUMANcleavageNetPath

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05214Glioma
hsa05169Epstein-Barr virus infection
hsa04722Neurotrophin signaling pathway
hsa04664Fc epsilon RI signaling pathway
hsa04530Tight junction
hsa05145Toxoplasmosis
hsa05164Influenza A
hsa05211Renal cell carcinoma
hsa04920Adipocytokine signaling pathway
hsa04914Progesterone-mediated oocyte maturation
hsa04620Toll-like receptor signaling pathway
hsa05213Endometrial cancer
hsa04660T cell receptor signaling pathway
hsa04725Cholinergic synapse
hsa04210Apoptosis
hsa05223Non-small cell lung cancer
hsa05220Chronic myeloid leukemia
hsa05210Colorectal cancer
hsa05222Small cell lung cancer
hsa05200Pathways in cancer
hsa05160Hepatitis C
hsa05218Melanoma
hsa05215Prostate cancer
hsa04973Carbohydrate digestion and absorption
hsa04910Insulin signaling pathway
hsa04666Fc gamma R-mediated phagocytosis
hsa05142Chagas disease (American trypanosomiasis)
hsa04062Chemokine signaling pathway
hsa05221Acute myeloid leukemia
hsa05212Pancreatic cancer
hsa05162Measles
hsa04728Dopaminergic synapse
hsa04370VEGF signaling pathway
hsa05166HTLV-I infection
hsa04510Focal adhesion
hsa04012ErbB signaling pathway
hsa04150mTOR signaling pathway
hsa04662B cell receptor signaling pathway
hsa04380Osteoclast differentiation
hsa04630Jak-STAT signaling pathway
hsa05152Tuberculosis
hsa04010MAPK signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0032880regulation of protein localizationIEAbiological_process
GO:0007165signal transductionTASbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0060644mammary gland epithelial cell differentiationTASbiological_process
GO:0005547phosphatidylinositol-3,4,5-trisphosphate bindingIDAmolecular_function
GO:0007281germ cell developmentIEAbiological_process
GO:0005737cytoplasmISScellular_component
GO:0043491protein kinase B signaling cascadeIEAbiological_process
GO:0035556intracellular signal transductionIDAbiological_process
GO:0032270positive regulation of cellular protein metabolic IEAbiological_process
GO:0016567protein ubiquitinationIEAbiological_process
GO:0046777protein autophosphorylationTASbiological_process
GO:0001934positive regulation of protein phosphorylationIDAbiological_process
GO:0016310phosphorylationIDAbiological_process
GO:0071364cellular response to epidermal growth factor stimuIEAbiological_process
GO:0019899enzyme bindingISSmolecular_function
GO:0006464cellular protein modification processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0050999regulation of nitric-oxide synthase activityTASbiological_process
GO:0032869cellular response to insulin stimulusIEAbiological_process
GO:0031999negative regulation of fatty acid beta-oxidationIMPbiological_process
GO:0006417regulation of translationIEAbiological_process
GO:0006468protein phosphorylationIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0042593glucose homeostasisIEAbiological_process
GO:0032270positive regulation of cellular protein metabolic ISSbiological_process
GO:0006006glucose metabolic processIEAbiological_process
GO:0006915apoptotic processTASbiological_process
GO:0010748negative regulation of plasma membrane long-chain IMPbiological_process
GO:0045907positive regulation of vasoconstrictionIEAbiological_process
GO:0005829cytosolIEAcellular_component
GO:0005819spindleIEAcellular_component
GO:0046329negative regulation of JNK cascadeIEAbiological_process
GO:0005543phospholipid bindingIEAmolecular_function
GO:0043536positive regulation of blood vessel endothelial ceIDAbiological_process
GO:0015758glucose transportIEAbiological_process
GO:0048009insulin-like growth factor receptor signaling pathIMPbiological_process
GO:0005634nucleusIEAcellular_component
GO:0010765positive regulation of sodium ion transportIEAbiological_process
GO:0070141response to UV-AIDAbiological_process
GO:0032436positive regulation of proteasomal ubiquitin-depenIEAbiological_process
GO:0019901protein kinase bindingIEAmolecular_function
GO:0005978glycogen biosynthetic processIEAbiological_process
GO:0071456cellular response to hypoxiaIEAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0001893maternal placenta developmentIEAbiological_process
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0015630microtubule cytoskeletonIDAcellular_component
GO:0006468protein phosphorylationIDAbiological_process
GO:0008283cell proliferationTASbiological_process
GO:0043154negative regulation of cysteine-type endopeptidaseIEAbiological_process
GO:0007568agingIEAbiological_process
GO:0031659positive regulation of cyclin-dependent protein kiIDAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0045429positive regulation of nitric oxide biosynthetic pIMPbiological_process
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0010467gene expressionTASbiological_process
GO:0016071mRNA metabolic processTASbiological_process
GO:0005080protein kinase C bindingIEAmolecular_function
GO:0030334regulation of cell migrationIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0006809nitric oxide biosynthetic processTASbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0090004positive regulation of establishment of protein loIMPbiological_process
GO:0009725response to hormone stimulusIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0008637apoptotic mitochondrial changesIEAbiological_process
GO:0030163protein catabolic processIEAbiological_process
GO:0010907positive regulation of glucose metabolic processIMPbiological_process
GO:0006469negative regulation of protein kinase activityIEAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0051091positive regulation of sequence-specific DNA bindiIDAbiological_process
GO:0060716labyrinthine layer blood vessel developmentIEAbiological_process
GO:0016301kinase activityIDAmolecular_function
GO:0010975regulation of neuron projection developmentIEAbiological_process
GO:0030030cell projection organizationIEAbiological_process
GO:0034405response to fluid shear stressIMPbiological_process
GO:0006924activation-induced cell death of T cellsIMPbiological_process
GO:0031018endocrine pancreas developmentTASbiological_process
GO:0001649osteoblast differentiationIEAbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0045600positive regulation of fat cell differentiationIMPbiological_process
GO:0009408response to heatTASbiological_process
GO:0046209nitric oxide metabolic processTASbiological_process
GO:0008286insulin receptor signaling pathwayIMPbiological_process
GO:0006412translationIEAbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0051000positive regulation of nitric-oxide synthase activIMPbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0032287peripheral nervous system myelin maintenanceIEAbiological_process
GO:0018105peptidyl-serine phosphorylationIEAbiological_process
GO:0004672protein kinase activityIEAmolecular_function
GO:0046889positive regulation of lipid biosynthetic processIMPbiological_process
GO:0090201negative regulation of release of cytochrome c froIEAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0045792negative regulation of cell sizeIEAbiological_process
GO:0008543fibroblast growth factor receptor signaling pathwaTASbiological_process
GO:0006915apoptotic processIEAbiological_process
GO:0031295T cell costimulationTASbiological_process
GO:0045725positive regulation of glycogen biosynthetic proceIMPbiological_process
GO:0019899enzyme bindingIEAmolecular_function
GO:0030027lamellipodiumIEAcellular_component
GO:0043325phosphatidylinositol-3,4-bisphosphate bindingIDAmolecular_function
GO:0046326positive regulation of glucose importIMPbiological_process
GO:0051146striated muscle cell differentiationIEAbiological_process
GO:0030235nitric-oxide synthase regulator activityIMPmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0048015phosphatidylinositol-mediated signalingTASbiological_process
GO:0042802identical protein bindingIPImolecular_function
GO:0030168platelet activationTASbiological_process
GO:0042640anagenIEAbiological_process
GO:2001047regulation of G1/S transition checkpointTASbiological_process
GO:0060709glycogen cell differentiation involved in embryoniIEAbiological_process
GO:0007173epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0005979regulation of glycogen biosynthetic processIMPbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0071363cellular response to growth factor stimulusIEAbiological_process
GO:0030307positive regulation of cell growthIEAbiological_process
GO:0005977glycogen metabolic processIEAbiological_process
GO:0033138positive regulation of peptidyl-serine phosphorylaIDAbiological_process
GO:0000060protein import into nucleus, translocationIMPbiological_process
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0030154cell differentiationTASbiological_process
GO:0032094response to foodIEAbiological_process