Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RAGE_HUMAN
Description:advanced glycosylation end product-specific receptor [Source:HGNC Symbol;Acc:320]
Location:chrHSCHR6_MHC_MANN p
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S391AELNQsEEPEAPhosphoSitePlus
S399PEAGEsSTGGPPhosphoSitePlus

Dephosphorylation site
RAGE_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000364217L388MCOSMICBreast Cancer

Differential expressed protein
RAGE_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RAGE_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
BMPR2_HUMANRAGE_HUMANkinase -> substrateRobert H Newman (2013)
RAGE_HUMANCSK22_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANRAGE_HUMANkinase -> substrateRobert H Newman (2013)
PLK1_HUMANRAGE_HUMANkinase -> substrateRobert H Newman (2013)
RAGE_HUMANMK07_HUMANkinase -> substrateRobert H Newman (2013)
FGFR1_HUMANRAGE_HUMANkinase -> substrateRobert H Newman (2013)
RAGE_HUMANSMAD4_HUMANkinase -> substrateRobert H Newman (2013)
RAGE_HUMANMBNL3_HUMANkinase -> substrateRobert H Newman (2013)
RAGE_HUMANSOX10_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
RAGE_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006954inflammatory responseIEAbiological_process
GO:0004888transmembrane signaling receptor activityTASmolecular_function
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0044548S100 protein bindingIPImolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0005886plasma membraneTAScellular_component
GO:0050930induction of positive chemotaxisIEAbiological_process
GO:0031175neuron projection developmentIGIbiological_process
GO:0051092positive regulation of NF-kappaB transcription facIDAbiological_process
GO:0045087innate immune responseTASbiological_process
GO:0005576extracellular regionIEAcellular_component
GO:0004872receptor activityTASmolecular_function
GO:0016020membraneIEAcellular_component
GO:0009611response to woundingTASbiological_process


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