Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ID2_HUMAN
Description:inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [Source:HGNC Symbol;Acc:5361]
Location:chr2 p25.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S5MKAFSpVRSVCDK2RegPhos
S44MNDCYsKLKELHLHPhosphoSitePlus
Y43NMNDCySKLKEHLHPhosphoSitePlus
S5VRSVCDK2HPRD; phosphoELM

Dephosphorylation site
ID2_HUMAN do not have dephosphorylation site.

Mutation site
ID2_HUMAN do not have mutation site.

Differential expressed protein
ID2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ID2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANID2_HUMANkinase -> substrateNetPath; Robert H Newman (2013)
AKT1_HUMANID2_HUMANkinase -> substrateRobert H Newman (2013)
ARBK1_HUMANID2_HUMANkinase -> substrateRobert H Newman (2013)
CDK2_HUMANID2_HUMANkinase -> substrateHPRD; RegPhos; NetPath

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05202Transcriptional misregulation in cancer
hsa04350TGF-beta signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045665negative regulation of neuron differentiationISSbiological_process
GO:0060612adipose tissue developmentIEAbiological_process
GO:0033598mammary gland epithelial cell proliferationISSbiological_process
GO:0048557embryonic digestive tract morphogenesisIEAbiological_process
GO:0005829cytosolIEAcellular_component
GO:0007275multicellular organismal developmentTASbiological_process
GO:0045578negative regulation of B cell differentiationIEAbiological_process
GO:0048469cell maturationIEAbiological_process
GO:0045668negative regulation of osteoblast differentiationIEAbiological_process
GO:2000045regulation of G1/S transition of mitotic cell cyclIMPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0003166bundle of His developmentIEAbiological_process
GO:0010628positive regulation of gene expressionIEAbiological_process
GO:0043353enucleate erythrocyte differentiationIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0021772olfactory bulb developmentIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0071285cellular response to lithium ionIEAbiological_process
GO:0043234protein complexISScellular_component
GO:0010629negative regulation of gene expressionIEAbiological_process
GO:2000178negative regulation of neural precursor cell proliISSbiological_process
GO:0048661positive regulation of smooth muscle cell proliferISSbiological_process
GO:0001779natural killer cell differentiationIEAbiological_process
GO:0044325ion channel bindingIPImolecular_function
GO:0014003oligodendrocyte developmentIEAbiological_process
GO:0045777positive regulation of blood pressureISSbiological_process
GO:0046983protein dimerization activityIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0048557embryonic digestive tract morphogenesisISSbiological_process
GO:0002521leukocyte differentiationIEAbiological_process
GO:0007507heart developmentIEAbiological_process
GO:0071931positive regulation of transcription involved in GICbiological_process
GO:0045787positive regulation of cell cycleIEAbiological_process
GO:0045648positive regulation of erythrocyte differentiationIEAbiological_process
GO:0045600positive regulation of fat cell differentiationIEAbiological_process
GO:0048661positive regulation of smooth muscle cell proliferIEAbiological_process
GO:0005829cytosolIDAcellular_component
GO:0048541Peyer's patch developmentIEAbiological_process
GO:0043433negative regulation of sequence-specific DNA bindiIDAbiological_process
GO:0048711positive regulation of astrocyte differentiationIEAbiological_process
GO:0060749mammary gland alveolus developmentIEAbiological_process
GO:0045651positive regulation of macrophage differentiationIEAbiological_process
GO:0048468cell developmentIEAbiological_process
GO:0071158positive regulation of cell cycle arrestISSbiological_process
GO:0090398cellular senescenceIEAbiological_process
GO:0061031endodermal digestive tract morphogenesisISSbiological_process
GO:0045893positive regulation of transcription, DNA-dependenISSbiological_process
GO:0061031endodermal digestive tract morphogenesisIEAbiological_process
GO:0090398cellular senescenceISSbiological_process
GO:0005634nucleusIEAcellular_component
GO:0043234protein complexIEAcellular_component
GO:0000785chromatinIEAcellular_component
GO:0048663neuron fate commitmentIEAbiological_process
GO:0048715negative regulation of oligodendrocyte differentiaIEAbiological_process
GO:0010629negative regulation of gene expressionISSbiological_process
GO:0061030epithelial cell differentiation involved in mammarIEAbiological_process
GO:0045665negative regulation of neuron differentiationIEAbiological_process
GO:0001656metanephros developmentIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0019216regulation of lipid metabolic processIEAbiological_process
GO:0060749mammary gland alveolus developmentISSbiological_process
GO:0061030epithelial cell differentiation involved in mammarISSbiological_process
GO:0033598mammary gland epithelial cell proliferationIEAbiological_process
GO:0071158positive regulation of cell cycle arrestIEAbiological_process
GO:0043392negative regulation of DNA bindingIEAbiological_process
GO:0045777positive regulation of blood pressureIEAbiological_process
GO:0009649entrainment of circadian clockIEAbiological_process
GO:2000178negative regulation of neural precursor cell proliIEAbiological_process
GO:0048663neuron fate commitmentISSbiological_process
GO:0010628positive regulation of gene expressionISSbiological_process
GO:0005634nucleusIDAcellular_component
GO:0008284positive regulation of cell proliferationIEAbiological_process