Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SPF45_HUMAN
Description:RNA binding motif protein 17 [Source:HGNC Symbol;Acc:16944]
Location:chr10 p15.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S227SPTGPsNSFLAPhosphoSitePlus; HPRD
S85KDPVPsGFSAGPhosphoSitePlus
S155RPDPDsDEDEDPhosphoSitePlus; HPRD; phosphoELM
S28FKLLQsQLQVKPhosphoSitePlus
Y194PRDFPyEEDSRPhosphoSitePlus
S180IAPPTsLVEKDPhosphoSitePlus
T179AIAPPtSLVEKPhosphoSitePlus; HPRD
S169ERRKRsMGGAAPhosphoSitePlus; HPRD; phosphoELM
T71RQIVDtPPHVAPhosphoSitePlus; HPRD
Y161DEDEDyERERRPhosphoSitePlus
S293SKKSDsNPLTEPhosphoSitePlus; HPRD
S204RPRSQsSKAAIPhosphoSitePlus; HPRD; phosphoELM
Y214IPPPVyEEQDRPhosphoSitePlus
S229TGPSNsFLANMPhosphoSitePlus; HPRD
S222QDRPRsPTGPSPhosphoSitePlus; HPRD; phosphoELM
T224RPRSPtGPSNSPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
SPF45_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000369218G247VBIOMARTBreast Cancer21930507, 21930502
ENSP00000388638G247VBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
SPF45_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SPF45_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK22_HUMANSPF45_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANSPF45_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSPF45_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANSPF45_HUMANkinase -> substrateRobert H Newman (2013)
DYRK3_HUMANSPF45_HUMANkinase -> substrateRobert H Newman (2013)
CSK21_HUMANSPF45_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SPF45_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005681spliceosomal complexIEAcellular_component
GO:0000166nucleotide bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0008380RNA splicingIEAbiological_process
GO:0006397mRNA processingIEAbiological_process


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