Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:LC7L2_HUMAN
Description:LUC7-like 2 (S. cerevisiae) [Source:HGNC Symbol;Acc:21608]
Location:chr7 q34
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S347DQDLAsCDRDRPhosphoSitePlus; HPRD; SysPTM
S353CDRDRsSRDRSPhosphoSitePlus; HPRD
S309RSRSSsRSRSRPhosphoSitePlus; HPRD
S327SSRDRsRERSKPhosphoSitePlus; HPRD
S307RHRSRsSSRSRHPRD
T17DQLMGtSRDGDHPRD; phosphoELM; SysPTM
S285RSRSMsRERKRPhosphoSitePlus; HPRD
T23SRDGDtTRQRIHPRD
T111KRLAEtQEEISHPRD; phosphoELM
S18QLMGTsRDGDTLUC7PhosphoSitePlus; SysPTM
S373KRSYEsANGRSPhosphoSitePlus
S384EDRRSsEEREAPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S378SANGRsEDRRSPhosphoSitePlus; HPRD
S18QLMGTsRDGDTHPRD; phosphoELM; SysPTM
S358SSRDRsPRDRDPhosphoSitePlus; HPRD; phosphoELM
T17DQLMGtSRDGDLUC7PhosphoSitePlus; SysPTM
S271KNPKRsRSREHPhosphoSitePlus; HPRD
S354DRDRSsRDRSPPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S305RHRHRsRSSSRPhosphoSitePlus; HPRD
T111KRLAEtQEEISLUC7PhosphoSitePlus
S281HRRHRsRSMSRPhosphoSitePlus; HPRD
S283RHRSRsMSRERPhosphoSitePlus; HPRD
S323RSRHSsRDRSRPhosphoSitePlus; HPRD
S383SEDRRsSEEREPhosphoSitePlus; HPRD; phosphoELM
S370KDKKRsYESANPhosphoSitePlus; HPRD
S308HRSRSsSRSRSHPRD
S273PKRSRsREHRRPhosphoSitePlus; HPRD

Dephosphorylation site
LC7L2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000263545E371GBIOMARTBreast Cancer21930507, 21930502
ENSP00000263545N374DBIOMARTBreast Cancer21930507, 21930502
ENSP00000347005N375DBIOMARTBreast Cancer21930507, 21930502
ENSP00000347005E372GBIOMARTBreast Cancer21930507, 21930502
ENSP00000347005P178ABIOMARTHepatocellular Carcinoma21930507, 21930502

Differential expressed protein
LC7L2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
LC7L2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PAK4_HUMANLC7L2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANLC7L2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
LC7L2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019899enzyme bindingIPImolecular_function
GO:0016607nuclear speckIEAcellular_component
GO:0046872metal ion bindingIEAmolecular_function


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