Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ZRAB2_HUMAN
Description:zinc finger, RAN-binding domain containing 2 [Source:HGNC Symbol;Acc:13058]
Location:chr1 p31.1
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y114RENVEyIEREEPhosphoSitePlus; HPRD; phosphoELM
Y183ADLSKyNLDASPhosphoSitePlus; HPRD; phosphoELM
S290RKRSRsRSSSSDUF936PhosphoSitePlus
S280SSSSSsPERNRHPRD
S326SGSRSsSKKK_PhosphoSitePlus
S278SYSSSsSSPERHPRD
Y93CNTPKyAKLEEzf-RanBPPhosphoSitePlus
T90CNMCNtPKYAKzf-RanBPPhosphoSitePlus
S193SEEEDsNKKKSHPRD; phosphoELM
S188YNLDAsEEEDSZRANB2HPRD
S188YNLDAsEEEDSDUF936PhosphoSitePlus
S217RSSSRsSSPSSDUF936PhosphoSitePlus
S307RTRSRsPERRHHPRD; phosphoELM
S153VEDKEsEGEEEPhosphoSitePlus; HPRD; phosphoELM
S318RSSSGsSHSGSphosphoELM
S218SSSRSsSPSSSDUF936PhosphoSitePlus
S288RNRKRsRSRSSDUF936PhosphoSitePlus
S279YSSSSsSPERNHPRD
S275RKRSYsSSSSSDUF936PhosphoSitePlus
S9KNFRVsDGDWIPhosphoSitePlus; HPRD; phosphoELM
S307RTRSRsPESQVHPRD
Y124ESDGEyDEFGRPhosphoSitePlus; HPRD
S310SRSPEsQVIGEHPRD
S213SSHSRsSSRSSDUF936PhosphoSitePlus
S276KRSYSsSSSSPHPRD
S305KRRTRsRSPERHPRD; phosphoELM
S249SSRERsRSRGSHPRD
S305KRRTRsRSPESHPRD
S181DDADLsKYNLDPhosphoSitePlus; HPRD; phosphoELM
S323SSHSGsRSSSKPhosphoSitePlus
S188YNLDAsEEEDSHPRD; phosphoELM
S120IEREEsDGEYDPhosphoSitePlus; HPRD; phosphoELM
S208RSKSRsSHSRSDUF936PhosphoSitePlus
S277RSYSSsSSSPEHPRD
S307RTRSRsPERRHDUF936PhosphoSitePlus
Y102EERTGyGGGFNPhosphoSitePlus
S206RSRSKsRSSHSDUF936PhosphoSitePlus
S193SEEEDsNKKKSDUF936PhosphoSitePlus
S280SSSSSsPERNRDUF936PhosphoSitePlus
S305KRRTRsRSPERDUF936PhosphoSitePlus
T50MKAGGtEIGKTPhosphoSitePlus
S275RKRSYsSSSSSHPRD
T303RKKRRtRSRSPHPRD; phosphoELM
S245RSRSSsRERSRHPRD

Dephosphorylation site
ZRAB2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000254821R301*COSMICOvarian Cancer21720365
ENSP00000254821G35CCOSMICOvarian Cancer21720365

Differential expressed protein
ZRAB2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ZRAB2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANZRAB2_HUMANkinase -> substrateRobert H Newman (2013)
ZRAB2_HUMANZRAB2_HUMANkinase -> substrateHPRD
MP2K4_HUMANZRAB2_HUMANkinase -> substrateRobert H Newman (2013)
SRPK2_HUMANZRAB2_HUMANkinase -> substrateRobert H Newman (2013)
CSK22_HUMANZRAB2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANZRAB2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ZRAB2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005622intracellularIEAcellular_component
GO:0005634nucleusIEAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0006397mRNA processingIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0008380RNA splicingIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentTASbiological_process
GO:0003700sequence-specific DNA binding transcription factorTASmolecular_function


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