Tool Application


—— ExpCluster

ExpCluster is used to perform clustering analysis to quantitative dynamic phosphoproteomic data (~8 time points or fewer) with similar dynamic expression or phosphorylation patterns, by using STEM software.

    Select a file to upload:  
    Download an example file

    *Normalize_Data:     Log normalize data     Normalize data     No normalization/add 0

    *Clustering_Method:     STEM Clustering Method     K-means

                     

    Example (file format):
    SPOTGene/Protein Nametime(0)time(1)time(2)time(3)time(4)
    1ZFX-0.0270.1580.1690.193-0.165
    2DSCR1L1-0.923-0.51-0.718-0.512-0.668
    3TCF3-0.0210.129-0.209-0.2450.036
    .....................


—— CanReceptor

As we collected cancer related information at phosphorylation site level, sequence mutation level and protein expression level along the signaling transduction process for PhoSigNet, we developed another analysis platform CanReceptor to perform cancer-triggering receptor inference based on downstream enrichment analysis.

    Protein

    Protein Group

    Cancer Triggering Receptors
    Basic protein information
    Cancer-related information
    Direct interaction pairs    		 Protein summary
    Group interaction pairs    		 Receptors with statistical significance