Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:WIPI3_HUMAN
Description:WD repeat domain 45B [Source:HGNC Symbol;Acc:25072]
Location:chr17 q25.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T100EIEFStEVKAVPhosphoSitePlus
Y65LFRCNyLALVGPhosphoSitePlus

Dephosphorylation site
WIPI3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000376139T161MCOSMICCentral Nervous System Neoplasms21817013
ENSP00000376139Q229EBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
WIPI3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
WIPI3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PKN1_HUMANWIPI3_HUMANkinase -> substrateRobert H Newman (2013)
MARK2_HUMANWIPI3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANWIPI3_HUMANkinase -> substrateRobert H Newman (2013)
PXK_HUMANWIPI3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
WIPI3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000045autophagic vacuole assemblyIBAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0032266phosphatidylinositol-3-phosphate bindingIBAmolecular_function
GO:0080025phosphatidylinositol-3,5-bisphosphate bindingIBAmolecular_function
GO:0005737cytoplasmIBAcellular_component


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