| UniProt/SwissProt ID: | TSN_HUMAN |
| Description: | translin [Source:HGNC Symbol;Acc:12379] |
| Location: | chr2 q14.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y210 | VEEVVyDLSIR | Translin | PhosphoSitePlus |
| T70 | FGTVKtHLTSL | Translin | PhosphoSitePlus |
| Dephosphorylation site |
| TSN_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000374332 | S142L | COSMIC | Breast Cancer | ENSP00000374332 | T73A | COSMIC | Intestines Cancer | 17932254 |
| Differential expressed protein |
| TSN_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TSN_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| STK24_HUMAN | TSN_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| AKT1_HUMAN | TSN_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TSN_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0006310 | DNA recombination | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003729 | mRNA binding | IEA | molecular_function |
| GO:0004519 | endonuclease activity | IEA | molecular_function |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0003677 | DNA binding | TAS | molecular_function |