Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:XPA_HUMAN
Description:xeroderma pigmentosum, complementation group A [Source:HGNC Symbol;Acc:12814]
Location:chr9 q22.33
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S196LEVWGsQEALEDNAPKRegPhos
S196LEVWGsQEALEATMHPRD; RegPhos
S196LEVWGsQEALEATRHPRD; RegPhos
S173KNPHHsQWGDMDNAPKRegPhos
S173KNPHHsQWGDMXPA_CPhosphoSitePlus
Y257LEDDMyRKTCTDUF3797PhosphoSitePlus
S173KNPHHsQWGDMPRKDCHPRD
T239VWKREtIVHQHPhosphoSitePlus
Y48LAARPySATAAPhosphoSitePlus
S196LEVWGsQEALEPRKDCHPRD
S173KNPHHsQWGDMATRHPRD; RegPhos
S173KNPHHsQWGDMATMHPRD; RegPhos
S196LEVWGsQEALEPhosphoSitePlus; phosphoELM; RegPhos

Dephosphorylation site
XPA_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000364270K221ECOSMICBreast Cancer20668451

Differential expressed protein
XPA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
XPA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PRKDC_HUMANXPA_HUMANkinase -> substrateHPRD
ATR_HUMANXPA_HUMANkinase -> substrateRegPhos
AKT1_HUMANXPA_HUMANkinase -> substrateRobert H Newman (2013)
MK08_HUMANXPA_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANXPA_HUMANkinase -> substrateRegPhos
KS6A5_HUMANXPA_HUMANkinase -> substrateRobert H Newman (2013)
ATM_HUMANXPA_HUMANkinase -> substrateRegPhos
CLK2_HUMANXPA_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANXPA_HUMANkinase -> substrateRobert H Newman (2013)
DYRK3_HUMANXPA_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa03420Nucleotide excision repair

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006281DNA repairIEAbiological_process
GO:0006289nucleotide-excision repairIEAbiological_process
GO:0006979response to oxidative stressIEAbiological_process
GO:0003684damaged DNA bindingIEAmolecular_function
GO:0042803protein homodimerization activityIPImolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0006281DNA repairTASbiological_process
GO:0019904protein domain specific bindingIPImolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0008630intrinsic apoptotic signaling pathway in response IEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005654nucleoplasmTAScellular_component
GO:0009636response to toxinIEAbiological_process
GO:0000718nucleotide-excision repair, DNA damage removalTASbiological_process
GO:0006289nucleotide-excision repairTASbiological_process
GO:0009411response to UVIEAbiological_process
GO:0005634nucleusTAScellular_component
GO:0000166nucleotide bindingIEAmolecular_function


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