| UniProt/SwissProt ID: | GAS7_HUMAN |
| Description: | growth arrest-specific 7 [Source:HGNC Symbol;Acc:4169] |
| Location: | chr17 p13.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T153 | SVRKStGDSQN | PhosphoSitePlus | |
| S376 | KARRKsTQAGD | DUF1664 | PhosphoSitePlus |
| S165 | GSSSPsKKQSK | PhosphoSitePlus | |
| S156 | KSTGDsQNLGS | PhosphoSitePlus | |
| S120 | PASPGsHRSSL | PhosphoSitePlus | |
| T377 | ARRKStQAGDD | DUF1664 | PhosphoSitePlus |
| S117 | PGIPAsPGSHR | PhosphoSitePlus | |
| S148 | ETAHMsVRKST | PhosphoSitePlus | |
| S163 | NLGSSsPSKKQ | PhosphoSitePlus | |
| S152 | MSVRKsTGDSQ | PhosphoSitePlus | |
| Dephosphorylation site |
| GAS7_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000322608 | T377A | COSMIC | Lung Cancer | 20668451 | ENSP00000322608 | I359M | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000322608 | G91A | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| GAS7_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GAS7_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| AKT1_HUMAN | GAS7_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KPCA_HUMAN | GAS7_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| TNI3K_HUMAN | GAS7_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| GAS7_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030182 | neuron differentiation | IEA | biological_process |
| GO:0007050 | cell cycle arrest | TAS | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0001726 | ruffle | IEA | cellular_component |
| GO:0005884 | actin filament | IEA | cellular_component |
| GO:0003700 | sequence-specific DNA binding transcription factor | TAS | molecular_function |
| GO:0008360 | regulation of cell shape | IEA | biological_process |
| GO:0051015 | actin filament binding | IEA | molecular_function |
| GO:0051017 | actin filament bundle assembly | IEA | biological_process |
| GO:0030041 | actin filament polymerization | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | TAS | biological_process |
| GO:0048812 | neuron projection morphogenesis | IEA | biological_process |