Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GAS7_HUMAN
Description:growth arrest-specific 7 [Source:HGNC Symbol;Acc:4169]
Location:chr17 p13.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T153SVRKStGDSQNPhosphoSitePlus
S376KARRKsTQAGDDUF1664PhosphoSitePlus
S165GSSSPsKKQSKPhosphoSitePlus
S156KSTGDsQNLGSPhosphoSitePlus
S120PASPGsHRSSLPhosphoSitePlus
T377ARRKStQAGDDDUF1664PhosphoSitePlus
S117PGIPAsPGSHRPhosphoSitePlus
S148ETAHMsVRKSTPhosphoSitePlus
S163NLGSSsPSKKQPhosphoSitePlus
S152MSVRKsTGDSQPhosphoSitePlus

Dephosphorylation site
GAS7_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000322608T377ACOSMICLung Cancer20668451
ENSP00000322608I359MCOSMICHead and Neck Cancer21798893
ENSP00000322608G91ACOSMICHead and Neck Cancer21798893

Differential expressed protein
GAS7_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GAS7_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AKT1_HUMANGAS7_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANGAS7_HUMANkinase -> substrateRobert H Newman (2013)
TNI3K_HUMANGAS7_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
GAS7_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030182neuron differentiationIEAbiological_process
GO:0007050cell cycle arrestTASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0001726ruffleIEAcellular_component
GO:0005884actin filamentIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorTASmolecular_function
GO:0008360regulation of cell shapeIEAbiological_process
GO:0051015actin filament bindingIEAmolecular_function
GO:0051017actin filament bundle assemblyIEAbiological_process
GO:0030041actin filament polymerizationIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentTASbiological_process
GO:0048812neuron projection morphogenesisIEAbiological_process


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