Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ANM1_HUMAN
Description:protein arginine methyltransferase 1 [Source:HGNC Symbol;Acc:5187]
Location:chr19 q13.33
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T305THWKQtVFYMEPhosphoSitePlus
S297STSPEsPYTHWPhosphoSitePlus
T300PESPYtHWKQTPhosphoSitePlus
Y299SPESPyTHWKQPhosphoSitePlus; phosphoELM
Y309SPESPyTHWKQHPRD
Y43TSKDYyFDSYAPhosphoSitePlus
Y42MTSKDyYFDSYPhosphoSitePlus

Dephosphorylation site
ANM1_HUMAN do not have dephosphorylation site.

Mutation site
ANM1_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000406162Breast CancerNormal vs. Cancercell lineDown0.5920543960

Hyperphosphorylation site
ANM1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AKT1_HUMANANM1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ANM1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0044020histone methyltransferase activity (H4-R3 specificIDAmolecular_function
GO:0016275[cytochrome c]-arginine N-methyltransferase activiIEAmolecular_function
GO:0008170N-methyltransferase activityIDAmolecular_function
GO:0008276protein methyltransferase activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0042054histone methyltransferase activityIDAmolecular_function
GO:0018216peptidyl-arginine methylationIDAbiological_process
GO:0005654nucleoplasmIEAcellular_component
GO:0035246peptidyl-arginine N-methylationIEAbiological_process
GO:0006479protein methylationTASbiological_process
GO:0043985histone H4-R3 methylationIDAbiological_process
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimIEAbiological_process
GO:0030519snoRNP bindingIEAmolecular_function
GO:0008152metabolic processIEAbiological_process
GO:0016274protein-arginine N-methyltransferase activityIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0005737cytoplasmTAScellular_component
GO:0008168methyltransferase activityTASmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0018216peptidyl-arginine methylationIEAbiological_process
GO:0031175neuron projection developmentIMPbiological_process
GO:0035241protein-arginine omega-N monomethyltransferase actIEAmolecular_function
GO:0045653negative regulation of megakaryocyte differentiatiIDAbiological_process
GO:0016571histone methylationIDAbiological_process
GO:0008469histone-arginine N-methyltransferase activityIEAmolecular_function
GO:0035247peptidyl-arginine omega-N-methylationIEAbiological_process
GO:0005829cytosolIEAcellular_component
GO:0016740transferase activityIEAmolecular_function
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0043234protein complexIEAcellular_component
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0035242protein-arginine omega-N asymmetric methyltransferIEAmolecular_function


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