Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SYNJ2_HUMAN
Description:synaptojanin 2 [Source:HGNC Symbol;Acc:11504]
Location:chr6 q25.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S1433TWLSKsSDPLDPhosphoSitePlus
S994SPTANsCLLEEPhosphoSitePlus
T1220AAKPEtPQAPPPhosphoSitePlus
S1191ARGGAsEEALSPhosphoSitePlus; HPRD
S1318PGAGAsVPPPLPhosphoSitePlus
T991APVSPtANSCLPhosphoSitePlus
S825LNLLDsDLDVDExo_endo_phosPhosphoSitePlus; SysPTM
S1434WLSKSsDPLDSPhosphoSitePlus
Y1136GTHGQySILQTPhosphoSitePlus
S4__MALsKGLRLPhosphoSitePlus
Y490LVGDVyGEEVAPhosphoSitePlus
S1124VKKSAsDASISPhosphoSitePlus
Y130SSGVFyFSWPNHPRD; phosphoELM
S1196SEEALsAVAPRPhosphoSitePlus
S1122LMVKKsASDASPhosphoSitePlus
S921MQTLGsYGTIVPhosphoSitePlus
Y130SSGVFyFSWPNSyja_NPhosphoSitePlus
T1441PLDSGtRSPKRPhosphoSitePlus
Y61KLTDAyGCLGESyja_NPhosphoSitePlus
S825LNLLDsDLDVDHPRD; SysPTM
T918TELMQtLGSYGPhosphoSitePlus
Y1411PLLGDyQDPFWPhosphoSitePlus
S1439SDPLDsGTRSPPhosphoSitePlus

Dephosphorylation site
SYNJ2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000347792M534ICOSMICSkin Cancer21984974
ENSP00000347792R617CCOSMICHead and Neck Cancer21798893

Differential expressed protein
SYNJ2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SYNJ2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KS6B1_HUMANSYNJ2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANSYNJ2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SYNJ2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0006644phospholipid metabolic processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0046854phosphatidylinositol phosphorylationIEAbiological_process
GO:0006661phosphatidylinositol biosynthetic processTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0042578phosphoric ester hydrolase activityIEAmolecular_function
GO:0000166nucleotide bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0004439phosphatidylinositol-4,5-bisphosphate 5-phosphatasIEAmolecular_function
GO:0016020membraneIEAcellular_component


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