Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DNJB2_HUMAN
Description:DnaJ (Hsp40) homolog, subfamily B, member 2 [Source:HGNC Symbol;Acc:5228]
Location:chr2 q35
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y4EILDHPRD
S219LGLELsRREQQPhosphoSitePlus
S313TKRSPsPEEKAPhosphoSitePlus; SysPTM
T204QLKSVtINGVPPhosphoSitePlus
Y261QLAMAySLSEMUIMPhosphoSitePlus
S15VPRSAsADDIKHPRD
S3YEILHPRD
Y65HKREIyDRYGRDnaJPhosphoSitePlus
T78LTGTGtGPSRAPhosphoSitePlus
S202DGQLKsVTINGPhosphoSitePlus
T95PGFTFtFRSPEPhosphoSitePlus
T76EGLTGtGTGPSPhosphoSitePlus
T239TQVQQtPASCPPhosphoSitePlus
S13LDVPRsASADDHPRD

Dephosphorylation site
DNJB2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000338019P136LCOSMICSkin Cancer21984974

Differential expressed protein
DNJB2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DNJB2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ACVR1_HUMANDNJB2_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANDNJB2_HUMANkinase -> substrateRobert H Newman (2013)
BMR1B_HUMANDNJB2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
DNJB2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0032436positive regulation of proteasomal ubiquitin-depenIDAbiological_process
GO:0016234inclusion bodyIDAcellular_component
GO:0030433ER-associated protein catabolic processIDAbiological_process
GO:0090084negative regulation of inclusion body assemblyIDAbiological_process
GO:0031072heat shock protein bindingIEAmolecular_function
GO:0031593polyubiquitin bindingIDAmolecular_function
GO:0031398positive regulation of protein ubiquitinationIDAbiological_process
GO:0030544Hsp70 protein bindingIPImolecular_function
GO:0090086negative regulation of protein deubiquitinationIDAbiological_process
GO:0008285negative regulation of cell proliferationIGIbiological_process
GO:0030308negative regulation of cell growthIGIbiological_process
GO:0070628proteasome bindingIDAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0051082unfolded protein bindingIEAmolecular_function
GO:0000502proteasome complexIDAcellular_component
GO:0006986response to unfolded proteinTASbiological_process
GO:0006457protein foldingIEAbiological_process


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