Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AKTS1_HUMAN
Description:AKT1 substrate 1 (proline-rich) [Source:HGNC Symbol;Acc:28426]
Location:chr19 q13.33
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S211ENGPPsSPDLDSenescence_regPhosphoSitePlus
T198FKEKRtEARSSSenescence_regPhosphoSitePlus
T246RPRLNtSDFQKPKB_groupphosphoELM
S203TEARSsDEENGHPRD; phosphoELM; RegPhos
S116TETETsGEQLGRegPhos
T246RPRLNtSDFQKPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T246RPRLNtSDFQKAKT1HPRD; RegPhos
T246RPRLNtSDFQKAKT2HPRD; RegPhos
S202RTEARsSDEENHPRD; phosphoELM; RegPhos
S183QQYAKsLPVSVHPRD; phosphoELM; RegPhos; SysPTM
T198FKEKRtEARSSHPRD
T73AHRAAtAARPPPhosphoSitePlus; HPRD
S183QQYAKsLPVSVSenescence_regPhosphoSitePlus; SysPTM
T97SPPRPtLAREDPhosphoSitePlus; HPRD; phosphoELM
S221DRIAAsMRALVPhosphoSitePlus
S88APQPPsPTPSPPhosphoSitePlus; HPRD; phosphoELM; RegPhos
Y256KLKRKy_____PhosphoSitePlus
S202RTEARsSDEENSenescence_regPhosphoSitePlus
S212NGPPSsPDLDRSenescence_regPhosphoSitePlus; SysPTM
T90QPPSPtPSPPRPhosphoSitePlus; HPRD; phosphoELM
S211ENGPPsSPDLDHPRD; phosphoELM; RegPhos
T32ELVLLtAAPPPPhosphoSitePlus
S92PSPTPsPPRPTPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S203TEARSsDEENGSenescence_regPhosphoSitePlus
T246RPRLNtSDFQKAKT1(PKB) RegPhos
S247PRLNTsDFQKLPhosphoSitePlus
S212NGPPSsPDLDRHPRD; phosphoELM; RegPhos; SysPTM

Dephosphorylation site
AKTS1_HUMAN do not have dephosphorylation site.

Mutation site
AKTS1_HUMAN do not have mutation site.

Differential expressed protein
AKTS1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
AKTS1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AKT3_HUMANAKTS1_HUMANkinase -> substrateKEGG
AKT2_HUMANAKTS1_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANAKTS1_HUMANkinase -> substrateRegPhos
AKT1_HUMANAKTS1_HUMANkinase -> substrateHPRD; RegPhos
AKTS1_HUMANMTOR_HUMANkinase -> substrateKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04150mTOR signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043234protein complexIEAcellular_component
GO:0005634nucleusIEAcellular_component
GO:0045792negative regulation of cell sizeIDAbiological_process
GO:0007173epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0032007negative regulation of TOR signaling cascadeIEAbiological_process
GO:0044445cytosolic partIEAcellular_component
GO:0005829cytosolTAScellular_component
GO:0048011nerve growth factor receptor signaling pathwayIEAbiological_process
GO:0006469negative regulation of protein kinase activityIDAbiological_process
GO:0048015phosphatidylinositol-mediated signalingTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0008543fibroblast growth factor receptor signaling pathwaTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0031931TORC1 complexIDAcellular_component
GO:0043523regulation of neuron apoptotic processIEAbiological_process


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