Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:BMX_HUMAN
Description:BMX non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:1079]
Location:chrX p22.2
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y566VLDDQyVSSVGautocatalysis RegPhos
Y224NSKKIyGSQPNITKHPRD; RegPhos
Y566VLDDQyVSSVGSRCHPRD; phosphoELM; RegPhos
S425LKELGsGQFGVPkinase_TyrPhosphoSitePlus
Y224NSKKIyGSQPNBTKHPRD; phosphoELM; RegPhos
S568DDQYVsSVGTKPkinase_TyrPhosphoSitePlus
Y40KTNLSyYEYDKFAKRegPhos
Y566VLDDQyVSSVGSrcRegPhos
S261EDVASsNQKERCucumo_2BPhosphoSitePlus
Y440KWKGQyDVAVKPkinase_TyrPhosphoSitePlus
Y216TSLAQyDSNSKBTKHPRD; phosphoELM; RegPhos
S260SEDVAsSNQKECucumo_2BPhosphoSitePlus
Y216TSLAQyDSNSKPhosphoSitePlus
Y365YLAENyCFDSISH2PhosphoSitePlus
S226KKIYGsQPNFNPhosphoSitePlus
Y40KTNLSyYEYDKphosphoELM; RegPhos
Y224NSKKIyGSQPNTECHPRD; phosphoELM; RegPhos
Y40KTNLSyYEYDKPTK2HPRD
Y216TSLAQyDSNSKTECHPRD; RegPhos
Y224NSKKIyGSQPNTecRegPhos
Y40KTNLSyYEYDKPHPhosphoSitePlus
Y216TSLAQyDSNSKITKHPRD; RegPhos
Y566VLDDQyVSSVGPkinase_TyrPhosphoSitePlus
Y330SQVGMyTVSLFSH2PhosphoSitePlus
T34K.KKMSPNNYKERLFVLTK.TSysPTM 2.0

Dephosphorylation site
BMX_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000340082S212RTCGAOvarian Cancer21720365, 18772890
ENSP00000350224T418NDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502
ENSP00000350224S212RTCGAOvarian Cancer21720365, 18772890
ENSP00000350224K313QTCGAOvarian Cancer21720365, 18772890
ENSP00000340082R670WHPINon-small cell lung carcinoma17344846
ENSP00000308774S212RTCGAOvarian Cancer21720365, 18772890
ENSP00000340082T418NDing2008Lung Cancer18948947
ENSP00000350224R670WGreenman2007Lung Cancer17344846, 18428421
ENSP00000308774R670WHPINon-small cell lung carcinoma17344846
ENSP00000340082K313QTCGAOvarian Cancer21720365, 18772890
ENSP00000350224R670WHPINon-small cell lung carcinoma17344846
ENSP00000340082R670WGreenman2007Lung Cancer17344846, 18428421
ENSP00000308774R670WGreenman2007Lung Cancer17344846, 18428421
ENSP00000308774T418NDing2008Lung Cancer18948947
ENSP00000308774K313QTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
BMX_HUMAN is not differential expressed protein.

Hyperphosphorylation site
BMX_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ITK_HUMANBMX_HUMANkinase -> substrateRegPhos
TYRO3_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
KPCI_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANUFO_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANZN363_HUMANkinase -> substrateRobert H Newman (2013)
FGFR4_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
GRK5_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
SRC_HUMANBMX_HUMANkinase -> substrateHPRD; RegPhos
MK03_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANBPL1_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANCIP4_HUMANkinase -> substrateRobert H Newman (2013)
HIPK1_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANCRK_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANBMX_HUMANkinase -> substrateRegPhos
BMX_HUMANGPD1L_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANASAP3_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANRUFY1_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
BMX_HUMANHCLS1_HUMANkinase -> substrateRobert H Newman (2013)
BTK_HUMANBMX_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
BMX_HUMANUBE2A_HUMANkinase -> substrateRobert H Newman (2013)
KCC2D_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANANXA2_HUMANkinase -> substrateRobert H Newman (2013)
TGFR2_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANTSAP1_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANASAP2_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANCBL_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANHNRPK_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANZCH10_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANSRXN1_HUMANkinase -> substrateRobert H Newman (2013)
FAK1_HUMANBMX_HUMANkinase -> substrateHPRD; RegPhos; Robert H Newman (2013)
BMX_HUMANTRAT1_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANKPCB_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANHDAC3_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANIF4B_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANMBNL3_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMAN1433F_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANNPM_HUMANkinase -> substrateRobert H Newman (2013)
DYRK4_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANSND1_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANSUMO4_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANATX3_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANMTA1_HUMANkinase -> substrateRobert H Newman (2013)
PLK1_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANMAGAC_HUMANkinase -> substrateRobert H Newman (2013)
KS6A5_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANSTAR3_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANSRC8_HUMANkinase -> substrateRobert H Newman (2013)
PDPK1_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANIASPP_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
KC1D_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANGCFC1_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANVHL_HUMANkinase -> substrateRobert H Newman (2013)
TEC_HUMANBMX_HUMANkinase -> substrateRegPhos
BMX_HUMANRGCC_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANBCL3_HUMANkinase -> substrateRobert H Newman (2013)
BMR1A_HUMANBMX_HUMANkinase -> substrateRobert H Newman (2013)
BMX_HUMANTRIP6_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
BMX_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0004713protein tyrosine kinase activityTASmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005829cytosolTAScellular_component
GO:0005543phospholipid bindingIEAmolecular_function
GO:0046777protein autophosphorylationIDAbiological_process
GO:0032587ruffle membraneIDAcellular_component
GO:0046872metal ion bindingIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0035556intracellular signal transductionIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0004871signal transducer activityTASmolecular_function
GO:0007165signal transductionIDAbiological_process
GO:0004715non-membrane spanning protein tyrosine kinase actiIDAmolecular_function
GO:0006921cellular component disassembly involved in executiTASbiological_process
GO:0006915apoptotic processTASbiological_process
GO:0007155cell adhesionIEAbiological_process
GO:0006468protein phosphorylationTASbiological_process
GO:0007498mesoderm developmentTASbiological_process
GO:0006950response to stressIEAbiological_process