Phosphorylation

Protein information

UniProt/SwissProt ID:	ABI2_HUMAN
Description:	abl-interactor 2 [Source:HGNC Symbol;Acc:24011]
Location:	chr2 q33.2
Node attribute:	substrate

Position	PhosphoPeptide	Catalytic kinase	Source
S244	RTYSSsGSSGG		PhosphoSitePlus
S221	APSQQsPVRTA		HPRD
S218	RNMAPsQQSPV		HPRD
Y213	VVPNDyVPSPT		PhosphoSitePlus
T463	AIYDYtKDKED	SH3_1	PhosphoSitePlus
S183	TQKPPsPPMSG		PhosphoSitePlus
S224	RNMAPsQQSPV		PhosphoSitePlus; phosphoELM
T178	RTTPPtQKPPS		PhosphoSitePlus
S227	APSQQsPVRTA		PhosphoSitePlus; phosphoELM; SysPTM
S216	NDYVPsPTRNM		PhosphoSitePlus; phosphoELM
Y241	QRNRTySSSGS		PhosphoSitePlus
T200	HSPYRtLEPVR		PhosphoSitePlus
T294	PASRHtPPTIG		HPRD
Y460	KVVAIyDYTKD	SH3_1	PhosphoSitePlus
S301	PTIGGsLPYRR		HPRD
T218	YVPSPtRNMAP		PhosphoSitePlus
Y284	HPVQFySMNRP		HPRD
Y23	ALFDSyTNLER	PhoU	PhosphoSitePlus
S233	PVRTAsVNQRN		PhosphoSitePlus
S196	TLGRHsPYRTL		PhosphoSitePlus
Y32	ERVADyCENNY	PhoU	PhosphoSitePlus
Y371	GGSLPyRRPPS		PhosphoSitePlus
T361	PASRHtPPTIG		PhosphoSitePlus
S253	GGSHPsSRSSS		PhosphoSitePlus
S242	RNRTYsSSGSS		PhosphoSitePlus
S210	NDYVPsPTRNM		HPRD
S368	PTIGGsLPYRR		PhosphoSitePlus
T297	RHTPPtIGGSL		HPRD
T240	NQRNRtYSSSG		PhosphoSitePlus
Y198	GRHSPyRTLEP		PhosphoSitePlus

ABI2_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000261016	E394Q	BIOMART	Breast Cancer	21930507, 21930502

ABI2_HUMAN is not differential expressed protein.

ABI2_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
NEK9_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
AKT1_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
BMR1B_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
CDK5_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
PKN1_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
KPCI_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
BTK_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
ZAP70_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
GSK3B_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
ACK1_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
STYK1_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
TGFR2_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
CSK_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
SLTM_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
DYRK4_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
JAK2_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
DDR1_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)

KEGG Pathway

ABI2_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0006928	cellular component movement	IDA	biological_process
GO:0005913	cell-cell adherens junction	IEA	cellular_component
GO:0016358	dendrite development	IEA	biological_process
GO:0008093	cytoskeletal adaptor activity	TAS	molecular_function
GO:0008154	actin polymerization or depolymerization	NAS	biological_process
GO:0030175	filopodium	IDA	cellular_component
GO:0031625	ubiquitin protein ligase binding	IPI	molecular_function
GO:0070064	proline-rich region binding	IPI	molecular_function
GO:0017124	SH3 domain binding	IPI	molecular_function
GO:0005856	cytoskeleton	IEA	cellular_component
GO:0007010	cytoskeleton organization	TAS	biological_process
GO:0019900	kinase binding	NAS	molecular_function
GO:0005515	protein binding	IEA	molecular_function
GO:0003677	DNA binding	TAS	molecular_function
GO:0016477	cell migration	TAS	biological_process
GO:0043010	camera-type eye development	IEA	biological_process
GO:0016477	cell migration	IEA	biological_process
GO:0005829	cytosol	IDA	cellular_component
GO:0030425	dendrite	IEA	cellular_component
GO:0018108	peptidyl-tyrosine phosphorylation	IDA	biological_process
GO:0005737	cytoplasm	TAS	cellular_component
GO:0007611	learning or memory	IEA	biological_process
GO:0030027	lamellipodium	IDA	cellular_component

Human Phosphorylation Mediated
Signaling Transduction Network