Phosphorylation

You are querying signaling transduction network mediated by EDNRB_HUMAN in Thyroid Carcinoma.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	EDN3_HUMAN	EDNRB_HUMAN	ligand -> receptor	HPMR
2	EDNRB_HUMAN	GNAI3_HUMAN	GPCR -> Gprotein	gpDB
3	EDNRB_HUMAN	GNAI1_HUMAN	GPCR -> Gprotein	gpDB
4	EDNRB_HUMAN	GNA13_HUMAN	GPCR -> Gprotein	gpDB
5	EDNRB_HUMAN	GNAI2_HUMAN	GPCR -> Gprotein	gpDB
6	EDNRB_HUMAN	GNAQ_HUMAN	GPCR -> Gprotein	gpDB
7	EDNRB_HUMAN	GNAO_HUMAN	GPCR -> Gprotein	gpDB
8	EDNRB_HUMAN	GNA11_HUMAN	GPCR -> Gprotein	gpDB
9	GNAI3_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
10	GNAI1_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
11	GNA13_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
12	GNAI3_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
13	GNAI1_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
14	GNAI2_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
15	GNAQ_HUMAN	BTK_HUMAN	Gprotein -> effector	gpDB
16	GNAQ_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
17	GNAI1_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
18	GNAO_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
19	GNAI2_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
20	GNAO_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
21	GNAI3_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
22	GNAQ_HUMAN	PK3CA_HUMAN	Gprotein -> effector	gpDB
23	GNAI2_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
24	GNA11_HUMAN	ARBK1_HUMAN	Gprotein -> effector	gpDB
25	GNAQ_HUMAN	KPCD1_HUMAN	Gprotein -> effector	gpDB
26	CSK_HUMAN	LCK_HUMAN	kinase -> substrate	HPRD; RegPhos
27	CSK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
28	CSK_HUMAN	FGR_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
29	KPCD1_HUMAN	KSYK_HUMAN	kinase -> substrate	NetPath
30	SRC_HUMAN	AKT1_HUMAN	kinase -> substrate	RegPhos
31	RAC1_HUMAN	MK08_HUMAN	kinase -> substrate; other	KEGG
32	CSK_HUMAN	FYN_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
33	BTK_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
34	ARBK1_HUMAN	P53_HUMAN	kinase -> substrate	Robert H Newman (2013)
35	BTK_HUMAN	MK01_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	CSK_HUMAN	LYN_HUMAN	kinase -> substrate; other	HPRD; RegPhos; Robert H Newman (2013); KEGG
37	SRC_HUMAN	RHG35_HUMAN	kinase -> substrate	KEGG; HPRD; RegPhos
38	SRC_HUMAN	FAK1_HUMAN	kinase -> substrate	RegPhos; NetPath
39	SRC_HUMAN	IKKB_HUMAN	kinase -> substrate	NetPath
40	BTK_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
41	SRC_HUMAN	RAF1_HUMAN	kinase -> substrate	HPRD; RegPhos
42	SRC_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos
43	BTK_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
44	PK3CA_HUMAN	KS6B1_HUMAN	kinase -> substrate	HPRD
45	SRC_HUMAN	ABL1_HUMAN	kinase -> substrate	RegPhos
46	SRC_HUMAN	ESR1_HUMAN	kinase -> substrate	HPRD; RegPhos
47	SRC_HUMAN	IGF1R_HUMAN	kinase -> substrate	RegPhos
48	BTK_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
49	CSK_HUMAN	ANDR_HUMAN	kinase -> substrate	RegPhos
50	SRC_HUMAN	HNRPK_HUMAN	kinase -> substrate	RegPhos
51	SRC_HUMAN	EGFR_HUMAN	kinase -> substrate	RegPhos
52	CSK_HUMAN	YES_HUMAN	kinase -> substrate	Robert H Newman (2013)
53	SRC_HUMAN	PDPK1_HUMAN	kinase -> substrate	RegPhos
54	BTK_HUMAN	CDK9_HUMAN	kinase -> substrate	Robert H Newman (2013)
55	BTK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
56	SRC_HUMAN	KPCI_HUMAN	kinase -> substrate	RegPhos
57	BTK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
58	SRC_HUMAN	STAT3_HUMAN	kinase -> substrate	HPRD; RegPhos
59	SRC_HUMAN	IKKA_HUMAN	kinase -> substrate	NetPath
60	CSK_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	SRC_HUMAN	SHC1_HUMAN	kinase -> substrate	RegPhos
62	BTK_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
63	CSK_HUMAN	PTPRC_HUMAN	kinase -> substrate	Robert H Newman (2013)
64	SRC_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
65	CSK_HUMAN	MK15_HUMAN	kinase -> substrate	RegPhos
66	SRC_HUMAN	DDR2_HUMAN	kinase -> substrate	RegPhos
67	CSK_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
68	SRC_HUMAN	KIT_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
69	BTK_HUMAN	STA5A_HUMAN	kinase -> substrate	HPRD; RegPhos
70	BTK_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
71	BTK_HUMAN	STA5B_HUMAN	kinase -> substrate	Robert H Newman (2013)
72	SRC_HUMAN	STA5B_HUMAN	kinase -> substrate	HPRD; RegPhos
73	BTK_HUMAN	ITK_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
74	LCK_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
75	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
76	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
77	KSYK_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
78	AKT1_HUMAN	FOXO1_HUMAN	kinase -> substrate	RegPhos; NetPath
79	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
80	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
81	FYN_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
82	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
83	MK01_HUMAN	TFE2_HUMAN	kinase -> substrate	HPRD; NetPath
84	MK01_HUMAN	SP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
85	LYN_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
86	RHG35_HUMAN	GCR_HUMAN	TF -> target gene	TRANSFAC
87	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
88	FAK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
89	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
90	IKKB_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD; NetPath; Robert H Newman (2013)
91	LYN_HUMAN	CDK1_HUMAN	kinase -> substrate	HPRD; RegPhos
92	LCK_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
93	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
94	AKT1_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos
95	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
96	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
97	AKT1_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
98	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
99	RAF1_HUMAN	MP2K1_HUMAN	kinase -> substrate; other	RegPhos; Robert H Newman (2013); KEGG
100	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
101	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
102	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
103	KS6B1_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
104	FYN_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
105	ABL1_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
106	ESR1_HUMAN	PRGR_HUMAN	TF -> target gene	TRANSFAC
107	IGF1R_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
108	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
109	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
110	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
111	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
112	FYN_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
113	FAK1_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
114	EGFR_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
115	YES_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
116	PDPK1_HUMAN	KPCD_HUMAN	kinase -> substrate	HPRD; RegPhos
117	RAF1_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
118	PDPK1_HUMAN	PKN1_HUMAN	kinase -> substrate	RegPhos
119	KS6B1_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
120	AKT1_HUMAN	GATA2_HUMAN	kinase -> substrate	HPRD
121	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
122	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
123	AKT1_HUMAN	STAT6_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	AKT1_HUMAN	M3K11_HUMAN	kinase -> substrate	HPRD; RegPhos
125	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
126	CDK9_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
127	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
128	AKT1_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
129	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
130	KPCI_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
131	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
132	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
133	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
134	AKT1_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos
135	PDPK1_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD; RegPhos
136	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
137	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
138	AKT1_HUMAN	GSK3B_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
139	MK01_HUMAN	MYC_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
140	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
141	IKKB_HUMAN	TF65_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
142	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
143	PDPK1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
144	AKT1_HUMAN	EP300_HUMAN	kinase -> substrate	HPRD; RegPhos
145	PDPK1_HUMAN	MP2K1_HUMAN	kinase -> substrate	RegPhos
146	MK01_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
147	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
148	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
149	STAT3_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
150	LYN_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
151	IKKA_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
152	ETS1_HUMAN	AP2A_HUMAN	TF -> target gene	TRANSFAC
153	KS6A2_HUMAN	SRF_HUMAN	kinase -> substrate	RegPhos
154	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
155	MK01_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD
156	YES_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
157	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
158	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
159	AKT1_HUMAN	GATA1_HUMAN	kinase -> substrate	HPRD; RegPhos
160	MK01_HUMAN	ELK1_HUMAN	kinase -> substrate	NetPath
161	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
162	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
163	PDPK1_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
164	KPCI_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
165	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
166	IKKA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD; NetPath
167	AKT1_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD; RegPhos
168	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
169	AKT1_HUMAN	SOX9_HUMAN	kinase -> substrate	Robert H Newman (2013)
170	KS6B1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
171	LYN_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
172	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
173	SHC1_HUMAN	ZAP70_HUMAN	kinase -> substrate	HPRD
174	ABL1_HUMAN	P73_HUMAN	kinase -> substrate	HPRD; RegPhos
175	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
176	ETS1_HUMAN	NFKB1_HUMAN	TF -> target gene	TRANSFAC
177	STAT3_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
178	KSYK_HUMAN	KS6A1_HUMAN	kinase -> substrate	NetPath
179	AKT1_HUMAN	THA_HUMAN	kinase -> substrate	Robert H Newman (2013)
180	KS6A2_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
181	PTPRC_HUMAN	JAK1_HUMAN	phosphatase -> substrate	HPRD
182	YES_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
183	LCK_HUMAN	ZAP70_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
184	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
185	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
186	MK01_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD
187	FYN_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
188	MK15_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
189	DDR2_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
190	KS6A2_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
191	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
192	KS6A2_HUMAN	KS6A1_HUMAN	kinase -> substrate	RegPhos
193	P53_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
194	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
195	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
196	ABL1_HUMAN	JUN_HUMAN	kinase -> substrate	HPRD; RegPhos
197	KSYK_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
198	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
199	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
200	KIT_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
201	MK01_HUMAN	RXRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
202	AKT1_HUMAN	MTOR_HUMAN	kinase -> substrate	RegPhos
203	LCK_HUMAN	VDR_HUMAN	kinase -> substrate	Robert H Newman (2013)
204	AKT1_HUMAN	GSK3A_HUMAN	kinase -> substrate	NetPath
205	AKT1_HUMAN	TEAD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
206	MK01_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD
207	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
208	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
209	ESR1_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
210	MK01_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
211	KS6B1_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
212	STA5A_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
213	STAT3_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
214	MK01_HUMAN	PKN1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
215	DDR2_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
216	MK01_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
217	LCK_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
218	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
219	KS6A2_HUMAN	CEBPB_HUMAN	kinase -> substrate	RegPhos
220	KS6A2_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
221	MK01_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
222	PDPK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
223	MK01_HUMAN	FOS_HUMAN	kinase -> substrate; other	KEGG
224	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
225	IKKA_HUMAN	NFKB1_HUMAN	kinase -> substrate; other	HPRD; NetPath; KEGG
226	MK01_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
227	MK01_HUMAN	STK16_HUMAN	kinase -> substrate	Robert H Newman (2013)
228	MK01_HUMAN	JUN_HUMAN	kinase -> substrate	KEGG
229	MK01_HUMAN	PRGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
230	MK01_HUMAN	THB_HUMAN	kinase -> substrate	Robert H Newman (2013)
231	MK01_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
232	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
233	MK01_HUMAN	SRBP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
234	MK01_HUMAN	GSK3B_HUMAN	kinase -> substrate	Robert H Newman (2013)
235	MK01_HUMAN	BCL6_HUMAN	kinase -> substrate	NetPath
236	MK01_HUMAN	PPARA_HUMAN	kinase -> substrate	HPRD
237	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
238	MK01_HUMAN	SOS1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
239	KS6B1_HUMAN	MTOR_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
240	ITK_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
241	MK01_HUMAN	SMAD4_HUMAN	kinase -> substrate	HPRD
242	MK01_HUMAN	CEBPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
243	KS6A2_HUMAN	FOS_HUMAN	kinase -> substrate	RegPhos
244	MK01_HUMAN	MP2K1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
245	MK01_HUMAN	SRBP2_HUMAN	kinase -> substrate	Robert H Newman (2013)
246	MK01_HUMAN	MITF_HUMAN	kinase -> substrate	NetPath
247	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
248	KS6A2_HUMAN	NR4A1_HUMAN	kinase -> substrate	RegPhos
249	MK01_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
250	KS6A2_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
251	MK01_HUMAN	MYB_HUMAN	kinase -> substrate	HPRD
252	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
253	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
254	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
255	CDK5_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
256	SP1_HUMAN	CDK2_HUMAN	TF -> target gene	TRANSFAC
257	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
258	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
259	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
260	CDK1_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
261	KPCD_HUMAN	NF2L2_HUMAN	kinase -> substrate	HPRD
262	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
263	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
264	KPCD_HUMAN	TWST1_HUMAN	kinase -> substrate	Robert H Newman (2013)
265	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
266	CDK1_HUMAN	E2F1_HUMAN	kinase -> substrate	RegPhos
267	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
268	FOXO1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
269	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
270	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
271	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
272	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
273	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
274	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
275	MK07_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
276	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
277	MK07_HUMAN	MEF2D_HUMAN	kinase -> substrate	HPRD
278	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
279	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
280	CDK1_HUMAN	HMGA1_HUMAN	kinase -> substrate	RegPhos
281	CDK5_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
282	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
283	M3K11_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
284	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
285	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
286	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
287	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
288	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
289	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
290	CDK1_HUMAN	HMGA2_HUMAN	kinase -> substrate	RegPhos
291	CDK5_HUMAN	MEF2D_HUMAN	kinase -> substrate	RegPhos
292	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
293	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
294	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
295	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
296	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
297	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
298	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
299	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
300	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
301	AP2A_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
302	SP1_HUMAN	AP2C_HUMAN	TF -> target gene	TRANSFAC
303	JAK1_HUMAN	STAT4_HUMAN	kinase -> substrate	RegPhos
304	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
305	RET_HUMAN	MK14_HUMAN	kinase -> substrate	HPRD; RegPhos
306	SP1_HUMAN	HNF4A_HUMAN	TF -> target gene	TRANSFAC
307	SP1_HUMAN	RARA_HUMAN	TF -> target gene	TRANSFAC
308	SP1_HUMAN	MAZ_HUMAN	TF -> target gene	TRANSFAC
309	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
310	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
311	SP1_HUMAN	PHX2A_HUMAN	TF -> target gene	TRANSFAC
312	SP1_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
313	CDK1_HUMAN	CUX1_HUMAN	kinase -> substrate	RegPhos
314	SP1_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
315	STK16_HUMAN	IRF5_HUMAN	kinase -> substrate	Robert H Newman (2013)
316	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
317	SP1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
318	SP1_HUMAN	SP3_HUMAN	TF -> target gene	TRANSFAC
319	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD
320	CDK7_HUMAN	PO2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
321	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
322	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
323	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
324	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
325	MP2K7_HUMAN	M3K7_HUMAN	kinase -> substrate	KEGG
326	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
327	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
328	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
329	TGFR2_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
330	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
331	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos
332	M3K7_HUMAN	NLK_HUMAN	kinase -> substrate	KEGG
333	M3K7_HUMAN	FUBP1_HUMAN	kinase -> substrate	Robert H Newman (2013)
334	NLK_HUMAN	LEF1_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
335	EDNRB_HUMAN	GNA12_HUMAN	GPCR -> Gprotein	gpDB

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network