Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MK15_HUMAN
Description:mitogen-activated protein kinase 15 [Source:HGNC Symbol;Acc:24667]
Location:chr8 q24.3
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y177QAVTEyVATRWCSKHPRD; RegPhos
Y177QAVTEyVATRWPkinasePhosphoSitePlus
T175EDQAVtEYVATErk7RegPhos
S192EVLLSsHRYTLPkinasePhosphoSitePlus
T175EDQAVtEYVATMAPK15HPRD
S362GPEGVsPSQAHPhosphoSitePlus
T175EDQAVtEYVATPkinasePhosphoSitePlus
Y340YRSRVyQMILEPhosphoSitePlus
S415VPRQNsAPLLQPhosphoSitePlus
T352GGSSGtSREKGPhosphoSitePlus
Y177QAVTEyVATRWRegPhos
S379DPQLPsRTPVQPhosphoSitePlus
T175EDQAVtEYVATRegPhos
S331EGVQLsVPEYRPhosphoSitePlus
Y177QAVTEyVATRWErk7RegPhos
Y177QAVTEyVATRWMAPK15HPRD
T381QLPSRtPVQGPPhosphoSitePlus
T175EDQAVtEYVATCSKHPRD; RegPhos

Dephosphorylation site
MK15_HUMAN do not have dephosphorylation site.

Mutation site
MK15_HUMAN do not have mutation site.

Differential expressed protein
MK15_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MK15_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANMK15_HUMANkinase -> substrateRegPhos
CSK_HUMANMK15_HUMANkinase -> substrateRegPhos
MK15_HUMANFGR_HUMANkinase -> substrateRobert H Newman (2013)
MK15_HUMANETS1_HUMANkinase -> substrateRobert H Newman (2013)
MK15_HUMANRET_HUMANkinase -> substrateRobert H Newman (2013)
MK15_HUMANMK15_HUMANkinase -> substrateHPRD
MK15_HUMANCBL_HUMANkinase -> substrateRobert H Newman (2013)
MK15_HUMANCSN6_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
MK15_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0000165MAPK cascadeIDAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0032355response to estradiol stimulusIEAbiological_process
GO:0008156negative regulation of DNA replicationIEAbiological_process
GO:0004672protein kinase activityIEAmolecular_function
GO:0001934positive regulation of protein phosphorylationIEAbiological_process
GO:0046777protein autophosphorylationIDAbiological_process
GO:0031398positive regulation of protein ubiquitinationIEAbiological_process
GO:0017124SH3 domain bindingNASmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0005622intracellularNAScellular_component
GO:0005576extracellular regionNAScellular_component
GO:0004707MAP kinase activityIDAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0045732positive regulation of protein catabolic processIEAbiological_process


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