Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:EGR3_HUMAN
Description:early growth response 3 [Source:HGNC Symbol;Acc:3240]
Location:chr8 p21.3
Node attribute:TF; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T326TTHIRtHTGEKzf-C2H2PhosphoSitePlus
T328HIRTHtGEKPFPhosphoSitePlus

Dephosphorylation site
EGR3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000318057G242SCOSMICHead and Neck Cancer21984974

Differential expressed protein
EGR3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
EGR3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EGR3_HUMANTNFL6_HUMANTF -> target geneTRANSFAC
NFAC2_HUMANEGR3_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
EGR3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0035924cellular response to vascular endothelial growth fIMPbiological_process
GO:0043066negative regulation of apoptotic processIMPbiological_process
GO:0003700sequence-specific DNA binding transcription factorTASmolecular_function
GO:0002042cell migration involved in sprouting angiogenesisIDAbiological_process
GO:0007623circadian rhythmTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0001938positive regulation of endothelial cell proliferatIMPbiological_process
GO:0005622intracellularIEAcellular_component
GO:0007422peripheral nervous system developmentIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0007517muscle organ developmentTASbiological_process
GO:0044344cellular response to fibroblast growth factor stimIMPbiological_process
GO:0007274neuromuscular synaptic transmissionIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0035767endothelial cell chemotaxisIMPbiological_process
GO:0008270zinc ion bindingIEAmolecular_function


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