UniProt/SwissProt ID: | RXRG_HUMAN |
Description: | retinoid X receptor, gamma [Source:HGNC Symbol;Acc:10479] |
Location: | chr1 q23.3 |
Node attribute: | substrate; TF |
Phosphorylation site |
Position | PhosphoPeptide | Catalytic kinase | Source |
---|---|---|---|
T294 | HFSDLtLEDQV | Hormone_recep | PhosphoSitePlus |
Y154 | KHYGVySCEGC | zf-C4 | PhosphoSitePlus |
Y398 | LREKVyATLEA | Hormone_recep | PhosphoSitePlus |
Y404 | ATLEAyTKQKY | Hormone_recep | PhosphoSitePlus |
Dephosphorylation site |
RXRG_HUMAN do not have dephosphorylation site. |
Mutation site |
Ensembl ID | Variation | Source | Cancer name | Pubmed |
---|---|---|---|---|
ENSP00000352900 | R176W | COSMIC | Skin Cancer | 21984974 |
Differential expressed protein |
RXRG_HUMAN is not differential expressed protein. |
Hyperphosphorylation site |
RXRG_HUMAN do not have hyperphosphorylation site. |
Direct Interaction Pair |
Source | Target | Relationship | Resource |
---|---|---|---|
KS6A1_HUMAN | RXRG_HUMAN | kinase -> substrate | Robert H Newman (2013) |
FGR_HUMAN | RXRG_HUMAN | kinase -> substrate | Robert H Newman (2013) |
ACVR1_HUMAN | RXRG_HUMAN | kinase -> substrate | Robert H Newman (2013) |
KPCA_HUMAN | RXRG_HUMAN | kinase -> substrate | Robert H Newman (2013) |
KS6A5_HUMAN | RXRG_HUMAN | kinase -> substrate | Robert H Newman (2013) |
RXRG_HUMAN | PSPB_HUMAN | TF -> target gene | TRANSFAC |
Function Annotation |
KEGG Pathway |
RXRG_HUMAN is not in KEGG pathway. |
Gene Ontology |
GO ID | GO_Term | Evidence | Ontology |
---|---|---|---|
GO:0031641 | regulation of myelination | IEA | biological_process |
GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
GO:0005654 | nucleoplasm | TAS | cellular_component |
GO:0007422 | peripheral nervous system development | IEA | biological_process |
GO:0007507 | heart development | IEA | biological_process |
GO:0006367 | transcription initiation from RNA polymerase II pr | TAS | biological_process |
GO:0003707 | steroid hormone receptor activity | IEA | molecular_function |
GO:0032870 | cellular response to hormone stimulus | IEA | biological_process |
GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |
GO:0007519 | skeletal muscle tissue development | IEA | biological_process |
GO:0030182 | neuron differentiation | IEA | biological_process |
GO:0043401 | steroid hormone mediated signaling pathway | IEA | biological_process |
GO:0004886 | 9-cis retinoic acid receptor activity | IEA | molecular_function |
GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
GO:0005634 | nucleus | IEA | cellular_component |
GO:0048384 | retinoic acid receptor signaling pathway | IEA | biological_process |
GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
GO:0032526 | response to retinoic acid | IEA | biological_process |
GO:0014070 | response to organic cyclic compound | IEA | biological_process |
GO:0010467 | gene expression | TAS | biological_process |
GO:0008270 | zinc ion binding | IEA | molecular_function |