| UniProt/SwissProt ID: | PO6F1_HUMAN |
| Description: | POU class 6 homeobox 1 [Source:HGNC Symbol;Acc:9224] |
| Location: | chr12 q13.13 |
| Node attribute: | substrate; TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T173 | VGQALtATEGP | Pou | PhosphoSitePlus |
| T166 | LGLTQtQVGQA | Pou | PhosphoSitePlus |
| T173 | VGQALtATEGP | HPRD | |
| T175 | QALTAtEGPAY | HPRD | |
| T175 | QALTAtEGPAY | Pou | PhosphoSitePlus |
| T166 | LGLTQtQVGQA | HPRD | |
| Dephosphorylation site |
| PO6F1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000330190 | A248S | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| PO6F1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PO6F1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KS6A4_HUMAN | PO6F1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| PO6F1_HUMAN | IL2_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| PO6F1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0007507 | heart development | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0007420 | brain development | TAS | biological_process |
| GO:0007517 | muscle organ development | TAS | biological_process |
| GO:0031965 | nuclear membrane | IDA | cellular_component |