Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GNAQ_HUMAN
Description:guanine nucleotide binding protein (G protein), q polypeptide [Source:HGNC Symbol;Acc:4390]
Location:chr9 q21.2
Node attribute:Gprotein; PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S154REYQLsDSTKYG-alphaPhosphoSitePlus
S198PFDLQsVIFRMG-alphaPhosphoSitePlus
S50LGTGEsGKSTFG-alphaPhosphoSitePlus
S53GESGKsTFIKQG-alphaPhosphoSitePlus

Dephosphorylation site
GNAQ_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000286548Y325FCOSMICHead and Neck Cancer21798893
ENSP00000286548R183QCOSMICHead and Neck Cancer21083380
ENSP00000286548Q209KCOSMICHead and Neck Cancer21874003
ENSP00000286548E249KCOSMICOvarian Cancer21720365
ENSP00000286548V359ICOSMICMelanoma
ENSP00000286548V182ICOSMICHead and Neck Cancer21083380
ENSP00000286548T175RCOSMICHead and Neck Cancer21083380

Differential expressed protein
GNAQ_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GNAQ_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CLTR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
TA2R_HUMANGNAQ_HUMANGPCR -> GproteingpDB
ACM5_HUMANGNAQ_HUMANGPCR -> GproteingpDB
TRFR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
CLTR1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
NMUR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
ACM3_HUMANGNAQ_HUMANGPCR -> GproteingpDB
P2RY2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PF2R_HUMANGNAQ_HUMANGPCR -> GproteingpDB
EDNRA_HUMANGNAQ_HUMANGPCR -> GproteingpDB
SUCR1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
GHSR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
P2Y11_HUMANGNAQ_HUMANGPCR -> GproteingpDB
LSHR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
LPAR3_HUMANGNAQ_HUMANGPCR -> GproteingpDB
5HT2A_HUMANGNAQ_HUMANGPCR -> GproteingpDB
LPAR1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
AGTR1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
5HT2B_HUMANGNAQ_HUMANGPCR -> GproteingpDB
GRM1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
ADA1D_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PAR3_HUMANGNAQ_HUMANGPCR -> GproteingpDB
P2RY6_HUMANGNAQ_HUMANGPCR -> GproteingpDB
MCHR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
5HT2C_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PE2R1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
BKRB1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
FZD2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
GALR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PE2R3_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PAR1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
ADA1A_HUMANGNAQ_HUMANGPCR -> GproteingpDB
FZD1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
LPAR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
V1BR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
MCHR1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
CASR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PAR4_HUMANGNAQ_HUMANGPCR -> GproteingpDB
CALCR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
LT4R1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
NK2R_HUMANGNAQ_HUMANGPCR -> GproteingpDB
LPAR4_HUMANGNAQ_HUMANGPCR -> GproteingpDB
NTR1_HUMANGNAQ_HUMANGPCR -> GproteingpDB
S1PR3_HUMANGNAQ_HUMANGPCR -> GproteingpDB
NK3R_HUMANGNAQ_HUMANGPCR -> GproteingpDB
S1PR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
ADA2A_HUMANGNAQ_HUMANGPCR -> GproteingpDB
NTR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
GNRHR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
LT4R2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PTAFR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PAR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
P2RY4_HUMANGNAQ_HUMANGPCR -> GproteingpDB
OXYR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
PRLHR_HUMANGNAQ_HUMANGPCR -> GproteingpDB
EDNRB_HUMANGNAQ_HUMANGPCR -> GproteingpDB
GNRR2_HUMANGNAQ_HUMANGPCR -> GproteingpDB
GNAQ_HUMANTBA3C_HUMANGprotein -> effectorgpDB
GNAQ_HUMANIRK3_HUMANGprotein -> effectorgpDB
GNAQ_HUMANPK3CA_HUMANGprotein -> effectorgpDB
GNAQ_HUMANARHGC_HUMANGprotein -> effectorgpDB
GNAQ_HUMANARBK1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANPLCB4_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB4B_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBA1C_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTTC1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBAL3_HUMANGprotein -> effectorgpDB
GNAQ_HUMANARBK2_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB8_HUMANGprotein -> effectorgpDB
GNAQ_HUMANIRK5_HUMANGprotein -> effectorgpDB
GNAQ_HUMANRIC8A_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBG2_HUMANGprotein -> effectorgpDB
GNAQ_HUMANIRK9_HUMANGprotein -> effectorgpDB
GNAQ_HUMANPLCB2_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB3_HUMANGprotein -> effectorgpDB
GNAQ_HUMANBTK_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB5_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBA1B_HUMANGprotein -> effectorgpDB
GNAQ_HUMANAKP13_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBE_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB4A_HUMANGprotein -> effectorgpDB
GNAQ_HUMANPK3CG_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBD_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBA1A_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBA4B_HUMANGprotein -> effectorgpDB
GNAQ_HUMANPLCB3_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBA3E_HUMANGprotein -> effectorgpDB
GNAQ_HUMANCAV1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANARHG1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANIRK6_HUMANGprotein -> effectorgpDB
GNAQ_HUMANPLCB1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANARHGB_HUMANGprotein -> effectorgpDB
GNAQ_HUMANNHRF1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBG1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANPK3CB_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBA4A_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB2B_HUMANGprotein -> effectorgpDB
GNAQ_HUMANKPCD1_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB6_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBA8_HUMANGprotein -> effectorgpDB
GNAQ_HUMANPLCB1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04720Long-term potentiation
hsa04723Retrograde endocannabinoid signaling
hsa04728Dopaminergic synapse
hsa05016Huntington's disease
hsa05143African trypanosomiasis
hsa05142Chagas disease (American trypanosomiasis)
hsa04726Serotonergic synapse
hsa04730Long-term depression
hsa05010Alzheimer's disease
hsa04970Salivary secretion
hsa04540Gap junction
hsa04916Melanogenesis
hsa04971Gastric acid secretion
hsa04972Pancreatic secretion
hsa05146Amoebiasis
hsa04020Calcium signaling pathway
hsa04270Vascular smooth muscle contraction
hsa04725Cholinergic synapse
hsa04961Endocrine and other factor-regulated calcium reabs
hsa04724Glutamatergic synapse
hsa04912GnRH signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004871signal transducer activityIEAmolecular_function
GO:0005096GTPase activator activityIDAmolecular_function
GO:0006471protein ADP-ribosylationIEAbiological_process
GO:0003924GTPase activityTASmolecular_function
GO:0031683G-protein beta/gamma-subunit complex bindingIBAmolecular_function
GO:0005737cytoplasmTAScellular_component
GO:0005886plasma membraneTAScellular_component
GO:0007507heart developmentIEAbiological_process
GO:0001508regulation of action potentialIEAbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0045634regulation of melanocyte differentiationIEAbiological_process
GO:0060158phospholipase C-activating dopamine receptor signaIEAbiological_process
GO:0030168platelet activationTASbiological_process
GO:0031234extrinsic to internal side of plasma membraneIBAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0001501skeletal system developmentIEAbiological_process
GO:0005525GTP bindingIEAmolecular_function
GO:0007215glutamate receptor signaling pathwayIEAbiological_process
GO:0006184GTP catabolic processTASbiological_process
GO:0042733embryonic digit morphogenesisIEAbiological_process
GO:0007189adenylate cyclase-activating G-protein coupled recIEAbiological_process
GO:0035412regulation of catenin import into nucleusIMPbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0048066developmental pigmentationIEAbiological_process
GO:0009791post-embryonic developmentIEAbiological_process
GO:0016322neuron remodelingIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0001664G-protein coupled receptor bindingIBAmolecular_function
GO:0050821protein stabilizationIMPbiological_process
GO:0005834heterotrimeric G-protein complexIBAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0021884forebrain neuron developmentIEAbiological_process
GO:0031965nuclear membraneIEAcellular_component
GO:0007610behaviorIEAbiological_process
GO:0006469negative regulation of protein kinase activityIMPbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0007202activation of phospholipase C activityTASbiological_process
GO:0043547positive regulation of GTPase activityIDAbiological_process
GO:0019001guanyl nucleotide bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function