| UniProt/SwissProt ID: | NFYA_HUMAN |
| Description: | nuclear transcription factor Y, alpha [Source:HGNC Symbol;Acc:7804] |
| Location: | chr6 p21.1 |
| Node attribute: | substrate; TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S291 | GGRFFsPKEKD | CDK2 | HPRD |
| Y266 | EEEPLyVNAKQ | CBFB_NFYA | PhosphoSitePlus |
| S320 | GGRFFsPKEKD | PhosphoSitePlus | |
| S297 | PKEKDsPHMQD | CDK2 | HPRD |
| S320 | GGRFFsPKEKD | CDK2 | HPRD |
| S326 | PKEKDsPHMQD | CDK2 | HPRD |
| S326 | PKEKDsPHMQD | PhosphoSitePlus; phosphoELM | |
| Dephosphorylation site |
| NFYA_HUMAN do not have dephosphorylation site. |
| Mutation site |
| NFYA_HUMAN do not have mutation site. |
| Differential expressed protein |
| NFYA_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NFYA_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK2_HUMAN | NFYA_HUMAN | kinase -> substrate | HPRD |
| NFYA_HUMAN | TGFR2_HUMAN | TF -> target gene | TRANSFAC |
| NFYA_HUMAN | E2F1_HUMAN | TF -> target gene | TRANSFAC |
| NFYA_HUMAN | CCNA2_HUMAN | TF -> target gene | TRANSFAC |
| NFYA_HUMAN | MDR1_HUMAN | TF -> target gene | TRANSFAC |
| NFYA_HUMAN | CDK1_HUMAN | TF -> target gene | TRANSFAC |
| NFYA_HUMAN | ZN267_HUMAN | TF -> target gene | TRANSFAC |
| NFYA_HUMAN | MYBA_HUMAN | TF -> target gene | TRANSFAC |
| NFYA_HUMAN | SOX3_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05152 | Tuberculosis |
| hsa04612 | Antigen processing and presentation |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0006366 | transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0016602 | CCAAT-binding factor complex | IDA | cellular_component |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | IDA | biological_process |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |