Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:EDN3_HUMAN
Description:endothelin 3 [Source:HGNC Symbol;Acc:3178]
Location:chr20 q13.32
Node attribute:ligand

Phosphorylation site
EDN3_HUMAN do not have phosphorylation site.

Dephosphorylation site
EDN3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000311854P121SCOSMICSkin Cancer21984974
ENSP00000311854L113MCOSMICHead and Neck Cancer21798893
ENSP00000311854S141YCOSMICHead and Neck Cancer21798893

Differential expressed protein
EDN3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
EDN3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EDN3_HUMANEDNRB_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
EDN3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030182neuron differentiationIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0007275multicellular organismal developmentTASbiological_process
GO:0030318melanocyte differentiationIEAbiological_process
GO:0005179hormone activityIDAmolecular_function
GO:0007267cell-cell signalingTASbiological_process
GO:0042310vasoconstrictionIDAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0014826vein smooth muscle contractionIDAbiological_process
GO:0007166cell surface receptor signaling pathwayIDAbiological_process
GO:0005102receptor bindingTASmolecular_function
GO:0048070regulation of developmental pigmentationIEAbiological_process
GO:0045840positive regulation of mitosisIDAbiological_process
GO:0043406positive regulation of MAP kinase activityIDAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0046887positive regulation of hormone secretionIDAbiological_process
GO:0030334regulation of cell migrationIEAbiological_process
GO:0007165signal transductionTASbiological_process
GO:0048016inositol phosphate-mediated signalingIDAbiological_process
GO:0001755neural crest cell migrationIEAbiological_process
GO:0030072peptide hormone secretionIDAbiological_process
GO:0019229regulation of vasoconstrictionIEAbiological_process
GO:0010460positive regulation of heart rateIDAbiological_process
GO:0002690positive regulation of leukocyte chemotaxisIDAbiological_process
GO:0030593neutrophil chemotaxisIDAbiological_process
GO:0008015blood circulationTASbiological_process
GO:0003100regulation of systemic arterial blood pressure by IDAbiological_process