Phosphorylation

You are querying signaling transduction network mediated by DDR1_HUMAN in Intestines Cancer.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	CO1A1_HUMAN	DDR1_HUMAN	ligand -> receptor	HPMR
2	DDR1_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
3	DDR1_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
4	DDR1_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
5	DDR1_HUMAN	CDK4_HUMAN	kinase -> substrate	RegPhos
6	DDR1_HUMAN	CDK2_HUMAN	kinase -> substrate	RegPhos
7	DDR1_HUMAN	CHK1_HUMAN	kinase -> substrate	Robert H Newman (2013)
8	DDR1_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
9	KPCA_HUMAN	EGFR_HUMAN	kinase -> substrate	Robert H Newman (2013)
10	KKCC1_HUMAN	AKT1_HUMAN	kinase -> substrate	HPRD
11	KS6A2_HUMAN	ESR1_HUMAN	kinase -> substrate	RegPhos
12	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
13	KS6A2_HUMAN	CEBPB_HUMAN	kinase -> substrate	RegPhos
14	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
15	CDK4_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
16	CDK4_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
17	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
18	CDK2_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
19	KPCA_HUMAN	SRC_HUMAN	kinase -> substrate; other	HPRD; KEGG
20	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos
21	CDK4_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
22	KS6A2_HUMAN	KS6A1_HUMAN	kinase -> substrate	RegPhos
23	KS6A2_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
24	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD
25	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
26	CDK2_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD; RegPhos
27	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
28	CDK2_HUMAN	P53_HUMAN	kinase -> substrate	RegPhos
29	CDK2_HUMAN	PRGR_HUMAN	kinase -> substrate	RegPhos
30	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
31	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
32	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
33	CDK2_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
34	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
35	KS6A2_HUMAN	NR4A1_HUMAN	kinase -> substrate	RegPhos
36	KS6A2_HUMAN	SRF_HUMAN	kinase -> substrate	RegPhos
37	KPCA_HUMAN	P53_HUMAN	kinase -> substrate	HPRD
38	CHK1_HUMAN	P73_HUMAN	kinase -> substrate	RegPhos
39	CDK2_HUMAN	SMAD3_HUMAN	kinase -> substrate	RegPhos
40	KS6A2_HUMAN	CSK_HUMAN	kinase -> substrate	Robert H Newman (2013)
41	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
42	KPCA_HUMAN	KIT_HUMAN	kinase -> substrate	HPRD; NetPath; Robert H Newman (2013)
43	KKCC1_HUMAN	KCC4_HUMAN	kinase -> substrate	HPRD
44	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
45	CHK1_HUMAN	CDK1_HUMAN	kinase -> substrate	KEGG
46	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
47	CDK2_HUMAN	P73_HUMAN	kinase -> substrate	HPRD; RegPhos
48	KPCA_HUMAN	PTN11_HUMAN	kinase -> substrate	HPRD
49	KPCA_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
50	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
51	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
52	KKCC1_HUMAN	CLK1_HUMAN	kinase -> substrate	Robert H Newman (2013)
53	KS6A2_HUMAN	FOS_HUMAN	kinase -> substrate	RegPhos
54	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
55	CDK4_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
56	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
57	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
58	KPCA_HUMAN	LCK_HUMAN	kinase -> substrate	HPRD
59	KS6A2_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
60	CDK4_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	KS6A2_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
62	KPCA_HUMAN	CSK_HUMAN	kinase -> substrate	HPRD
63	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
64	KPCA_HUMAN	PTN1_HUMAN	kinase -> substrate	Robert H Newman (2013)
65	CHK1_HUMAN	P53_HUMAN	kinase -> substrate	RegPhos
66	KS6A2_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
67	CDK4_HUMAN	SMAD3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
68	KS6A2_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
69	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
70	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
71	KPCA_HUMAN	PTPRR_HUMAN	kinase -> substrate	HPRD
72	KPCA_HUMAN	CTNB1_HUMAN	kinase -> substrate	KEGG
73	KPCA_HUMAN	FYN_HUMAN	kinase -> substrate	Robert H Newman (2013)
74	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
75	KS6A2_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
76	KPCA_HUMAN	FAK1_HUMAN	kinase -> substrate	KEGG
77	KPCA_HUMAN	KGP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
78	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
79	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
80	SOX10_HUMAN	MITF_HUMAN	TF -> target gene	TRANSFAC
81	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
82	CDK2_HUMAN	ESR1_HUMAN	kinase -> substrate	RegPhos
83	EGFR_HUMAN	STA5B_HUMAN	kinase -> substrate	RegPhos
84	AKT1_HUMAN	MTOR_HUMAN	kinase -> substrate	RegPhos
85	GSK3B_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
86	ETS1_HUMAN	AP2A_HUMAN	TF -> target gene	TRANSFAC
87	GSK3A_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
88	AKT1_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos
89	SRC_HUMAN	RHG35_HUMAN	kinase -> substrate	KEGG; HPRD; RegPhos
90	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
91	NFYA_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
92	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
93	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
94	GSK3B_HUMAN	FOXO1_HUMAN	kinase -> substrate	HPRD; RegPhos
95	CDK7_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
96	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
97	AKT1_HUMAN	GATA2_HUMAN	kinase -> substrate	HPRD
98	AKT1_HUMAN	FOXO1_HUMAN	kinase -> substrate	RegPhos; NetPath
99	P53_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
100	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
101	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
102	CSK_HUMAN	ANDR_HUMAN	kinase -> substrate	RegPhos
103	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
104	KIT_HUMAN	STA5A_HUMAN	kinase -> substrate	NetPath
105	KCC4_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
106	AKT1_HUMAN	M3K11_HUMAN	kinase -> substrate	HPRD; RegPhos
107	CDK1_HUMAN	CSK21_HUMAN	kinase -> substrate	RegPhos
108	AKT1_HUMAN	IKKA_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
109	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
110	PTN11_HUMAN	STA5A_HUMAN	phosphatase -> substrate	HPRD; NetPath
111	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
112	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
113	SRF_HUMAN	ELK1_HUMAN	TF -> target gene	TRANSFAC
114	CLK1_HUMAN	SRPK1_HUMAN	kinase -> substrate	Robert H Newman (2013)
115	PTN11_HUMAN	STA5B_HUMAN	phosphatase -> substrate	HPRD; NetPath
116	FOS_HUMAN	WEE1_HUMAN	TF -> target gene	TRANSFAC
117	LCK_HUMAN	IRAK1_HUMAN	kinase -> substrate	Robert H Newman (2013)
118	AKT1_HUMAN	TEAD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
119	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
120	CSK_HUMAN	YES_HUMAN	kinase -> substrate	Robert H Newman (2013)
121	SRC_HUMAN	IKKA_HUMAN	kinase -> substrate	NetPath
122	PTN1_HUMAN	STA5B_HUMAN	phosphatase -> substrate	HPRD
123	KIT_HUMAN	STA5B_HUMAN	kinase -> substrate	NetPath
124	EGFR_HUMAN	STA5A_HUMAN	kinase -> substrate	KEGG
125	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
126	GSK3B_HUMAN	CEBPA_HUMAN	kinase -> substrate	RegPhos
127	SRC_HUMAN	KPCI_HUMAN	kinase -> substrate	RegPhos
128	PTPRR_HUMAN	MK07_HUMAN	phosphatase -> substrate	HPRD
129	AKT1_HUMAN	GATA1_HUMAN	kinase -> substrate	HPRD; RegPhos
130	AKT1_HUMAN	THA_HUMAN	kinase -> substrate	Robert H Newman (2013)
131	GSK3B_HUMAN	MYC_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
132	FOS_HUMAN	MLTK_HUMAN	TF -> target gene	TRANSFAC
133	FYN_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
134	CDK7_HUMAN	E2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
135	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
136	AKT1_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
137	CDK7_HUMAN	PO2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
138	FYN_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
139	CSK_HUMAN	FGR_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
140	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
141	CDK1_HUMAN	ANDR_HUMAN	kinase -> substrate	NetPath
142	LCK_HUMAN	VDR_HUMAN	kinase -> substrate	Robert H Newman (2013)
143	SRC_HUMAN	STA5B_HUMAN	kinase -> substrate	HPRD; RegPhos
144	CDK1_HUMAN	HMGA2_HUMAN	kinase -> substrate	RegPhos
145	SMAD4_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
146	GSK3A_HUMAN	JUN_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
147	GSK3A_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos
148	CDK1_HUMAN	CUX1_HUMAN	kinase -> substrate	RegPhos
149	FAK1_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
150	AKT1_HUMAN	ANDR_HUMAN	kinase -> substrate	RegPhos; NetPath
151	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
152	LCK_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
153	GSK3B_HUMAN	ANDR_HUMAN	kinase -> substrate	NetPath
154	NFYA_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
155	KGP1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
156	CDK1_HUMAN	WEE1_HUMAN	kinase -> substrate	RegPhos
157	KS6A1_HUMAN	MTOR_HUMAN	kinase -> substrate	HPRD
158	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
159	PTN1_HUMAN	STA5A_HUMAN	phosphatase -> substrate	HPRD
160	KGP1_HUMAN	GTF2I_HUMAN	kinase -> substrate	HPRD
161	KGP1_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
162	CDK1_HUMAN	HMGA1_HUMAN	kinase -> substrate	RegPhos
163	CDK1_HUMAN	E2F1_HUMAN	kinase -> substrate	RegPhos
164	AKT1_HUMAN	IRAK1_HUMAN	kinase -> substrate	RegPhos
165	SRC_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos
166	AKT1_HUMAN	STAT6_HUMAN	kinase -> substrate	Robert H Newman (2013)
167	CDK7_HUMAN	RARA_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
168	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
169	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
170	AKT1_HUMAN	SOX9_HUMAN	kinase -> substrate	Robert H Newman (2013)
171	CDK1_HUMAN	GRK5_HUMAN	kinase -> substrate	Robert H Newman (2013)
172	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
173	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
174	AP2A_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
175	TGFR2_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
176	M3K11_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
177	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
178	IKKA_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
179	SRPK1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
180	WEE1_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
181	IRAK1_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
182	YES_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
183	KPCI_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
184	MK07_HUMAN	MEF2D_HUMAN	kinase -> substrate	HPRD
185	MLTK_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
186	CDK5_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
187	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
188	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
189	CDK5_HUMAN	MEF2D_HUMAN	kinase -> substrate	RegPhos
190	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
191	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
192	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
193	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
194	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
195	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
196	GRK5_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
197	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
198	MP2K7_HUMAN	M3K7_HUMAN	kinase -> substrate	KEGG
199	M3K7_HUMAN	NLK_HUMAN	kinase -> substrate	KEGG
200	M3K7_HUMAN	FUBP1_HUMAN	kinase -> substrate	Robert H Newman (2013)
201	NLK_HUMAN	LEF1_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
202	DDR1_HUMAN	ZN606_HUMAN	kinase -> substrate	Robert H Newman (2013)
203	DDR1_HUMAN	XPO1_HUMAN	kinase -> substrate	Robert H Newman (2013)
204	DDR1_HUMAN	NDF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
205	DDR1_HUMAN	HSFX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
206	DDR1_HUMAN	ZIC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
207	DDR1_HUMAN	MBNL3_HUMAN	kinase -> substrate	Robert H Newman (2013)
208	DDR1_HUMAN	ZNF32_HUMAN	kinase -> substrate	Robert H Newman (2013)
209	DDR1_HUMAN	NELFB_HUMAN	kinase -> substrate	Robert H Newman (2013)
210	DDR1_HUMAN	PER1_HUMAN	kinase -> substrate	Robert H Newman (2013)
211	ZAGL2_HUMAN	DDR1_HUMAN	kinase -> substrate	RegPhos
212	DDR1_HUMAN	MTA1_HUMAN	kinase -> substrate	Robert H Newman (2013)
213	DDR1_HUMAN	IASPP_HUMAN	kinase -> substrate	Robert H Newman (2013)
214	DDR1_HUMAN	PHB2_HUMAN	kinase -> substrate	Robert H Newman (2013)
215	DDR1_HUMAN	POLK_HUMAN	kinase -> substrate	Robert H Newman (2013)
216	DDR1_HUMAN	MDFI_HUMAN	kinase -> substrate	Robert H Newman (2013)
217	DDR1_HUMAN	ASAP3_HUMAN	kinase -> substrate	Robert H Newman (2013)
218	DDR1_HUMAN	FEV_HUMAN	kinase -> substrate	Robert H Newman (2013)
219	DDR1_HUMAN	DDR1_HUMAN	kinase -> substrate	HPRD; RegPhos
220	DDR1_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network