| UniProt/SwissProt ID: | ZN606_HUMAN |
| Description: | zinc finger protein 606 [Source:HGNC Symbol;Acc:25879] |
| Location: | chr19 q13.43 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T701 | IAHRRtHTGEK | zf-C2H2 | PhosphoSitePlus |
| T589 | IAHQRtHTGEK | zf-C2H2 | PhosphoSitePlus |
| T645 | VRHQRtHTGEK | zf-C2H2 | PhosphoSitePlus |
| T703 | HRRTHtGEKPY | PhosphoSitePlus | |
| T479 | HKRIHtGEKPY | PhosphoSitePlus | |
| T647 | HQRTHtGEKPY | PhosphoSitePlus | |
| T505 | IGHQRtHTGEK | zf-C2H2 | PhosphoSitePlus |
| T507 | HQRTHtGEKPF | PhosphoSitePlus | |
| S721 | AFNESsSLIVH | zf-C2H2; C1_4 | PhosphoSitePlus |
| T591 | HQRTHtGEKPY | PhosphoSitePlus | |
| S722 | FNESSsLIVHL | zf-C2H2; C1_4 | PhosphoSitePlus |
| T675 | HRRIHtGEKPY | PhosphoSitePlus | |
| Dephosphorylation site |
| ZN606_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000343617 | H694Y | COSMIC | Ovarian Cancer | 21720365 | ENSP00000343617 | H694N | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000343617 | S722A | COSMIC | Head and Neck Cancer | 21798897 |
| Differential expressed protein |
| ZN606_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZN606_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| DDR1_HUMAN | ZN606_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| DYR1B_HUMAN | ZN606_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SNRK_HUMAN | ZN606_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CLK2_HUMAN | ZN606_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| AURKB_HUMAN | ZN606_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK4_HUMAN | ZN606_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ZN606_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |