Phosphorylation

You are querying signaling transduction network mediated by 5HT1E_HUMAN in Lymphoma.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	TPH1_HUMAN	5HT1E_HUMAN	ligand -> receptor	HPMR
2	5HT1E_HUMAN	GNAI3_HUMAN	GPCR -> Gprotein	gpDB
3	5HT1E_HUMAN	GNAI2_HUMAN	GPCR -> Gprotein	gpDB
4	5HT1E_HUMAN	GNAI1_HUMAN	GPCR -> Gprotein	gpDB
5	5HT1E_HUMAN	GNAO_HUMAN	GPCR -> Gprotein	gpDB
6	GNAI3_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
7	GNAI2_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
8	GNAI2_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
9	GNAI3_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
10	GNAI1_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
11	GNAI2_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
12	GNAO_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
13	GNAO_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
14	GNAI3_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
15	GNAI1_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
16	GNAI1_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
17	RAC1_HUMAN	MK08_HUMAN	kinase -> substrate; other	KEGG
18	SRC_HUMAN	PDPK1_HUMAN	kinase -> substrate	RegPhos
19	SRC_HUMAN	ESR1_HUMAN	kinase -> substrate	HPRD; RegPhos
20	SRC_HUMAN	AKT1_HUMAN	kinase -> substrate	RegPhos
21	CSK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
22	CSK_HUMAN	LYN_HUMAN	kinase -> substrate; other	HPRD; RegPhos; Robert H Newman (2013); KEGG
23	SRC_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos
24	SRC_HUMAN	RHG35_HUMAN	kinase -> substrate	KEGG; HPRD; RegPhos
25	SRC_HUMAN	STAT3_HUMAN	kinase -> substrate	HPRD; RegPhos
26	SRC_HUMAN	HNRPK_HUMAN	kinase -> substrate	RegPhos
27	SRC_HUMAN	IKKA_HUMAN	kinase -> substrate	NetPath
28	CSK_HUMAN	FYN_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
29	CSK_HUMAN	FGR_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
30	SRC_HUMAN	RAF1_HUMAN	kinase -> substrate	HPRD; RegPhos
31	CSK_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
32	SRC_HUMAN	FAK1_HUMAN	kinase -> substrate	RegPhos; NetPath
33	SRC_HUMAN	DDR2_HUMAN	kinase -> substrate	RegPhos
34	SRC_HUMAN	STA5B_HUMAN	kinase -> substrate	HPRD; RegPhos
35	CSK_HUMAN	YES_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	CSK_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
37	SRC_HUMAN	KPCI_HUMAN	kinase -> substrate	RegPhos
38	SRC_HUMAN	ABL1_HUMAN	kinase -> substrate	RegPhos
39	CSK_HUMAN	MK15_HUMAN	kinase -> substrate	RegPhos
40	SRC_HUMAN	IKKB_HUMAN	kinase -> substrate	NetPath
41	CSK_HUMAN	LCK_HUMAN	kinase -> substrate	HPRD; RegPhos
42	SRC_HUMAN	KIT_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
43	CSK_HUMAN	ANDR_HUMAN	kinase -> substrate	RegPhos
44	SRC_HUMAN	EGFR_HUMAN	kinase -> substrate	RegPhos
45	CSK_HUMAN	PTPRC_HUMAN	kinase -> substrate	Robert H Newman (2013)
46	SRC_HUMAN	IGF1R_HUMAN	kinase -> substrate	RegPhos
47	SRC_HUMAN	SHC1_HUMAN	kinase -> substrate	RegPhos
48	SRC_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
49	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
50	PDPK1_HUMAN	MP2K1_HUMAN	kinase -> substrate	RegPhos
51	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
52	ESR1_HUMAN	PRGR_HUMAN	TF -> target gene	TRANSFAC
53	AKT1_HUMAN	M3K11_HUMAN	kinase -> substrate	HPRD; RegPhos
54	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
55	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
56	LYN_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
57	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
58	LYN_HUMAN	CDK1_HUMAN	kinase -> substrate	HPRD; RegPhos
59	RHG35_HUMAN	GCR_HUMAN	TF -> target gene	TRANSFAC
60	PDPK1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	STAT3_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
62	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
63	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
64	PDPK1_HUMAN	KPCD_HUMAN	kinase -> substrate	HPRD; RegPhos
65	IKKA_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
66	FYN_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
67	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
68	RAF1_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
69	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
70	FYN_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
71	ETS1_HUMAN	NFKB1_HUMAN	TF -> target gene	TRANSFAC
72	FAK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
73	AKT1_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
74	DDR2_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
75	AKT1_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
76	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
77	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
78	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
79	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
80	YES_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
81	IKKA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD; NetPath
82	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
83	AKT1_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos
84	AKT1_HUMAN	GSK3B_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
85	AKT1_HUMAN	GATA2_HUMAN	kinase -> substrate	HPRD
86	AKT1_HUMAN	FOXO1_HUMAN	kinase -> substrate	RegPhos; NetPath
87	YES_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
88	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
89	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
90	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
91	AKT1_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD; RegPhos
92	PDPK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
93	AKT1_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos
94	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
95	AKT1_HUMAN	GSK3A_HUMAN	kinase -> substrate	NetPath
96	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
97	PDPK1_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
98	AKT1_HUMAN	EP300_HUMAN	kinase -> substrate	HPRD; RegPhos
99	KPCI_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
100	ABL1_HUMAN	P73_HUMAN	kinase -> substrate	HPRD; RegPhos
101	PDPK1_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD; RegPhos
102	ETS1_HUMAN	AP2A_HUMAN	TF -> target gene	TRANSFAC
103	MK15_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
104	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
105	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
106	LYN_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
107	AKT1_HUMAN	GATA1_HUMAN	kinase -> substrate	HPRD; RegPhos
108	STAT3_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
109	PDPK1_HUMAN	PKN1_HUMAN	kinase -> substrate	RegPhos
110	STAT3_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
111	FYN_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
112	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
113	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
114	IKKA_HUMAN	NFKB1_HUMAN	kinase -> substrate; other	HPRD; NetPath; KEGG
115	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
116	FAK1_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
117	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
118	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
119	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
120	AKT1_HUMAN	THA_HUMAN	kinase -> substrate	Robert H Newman (2013)
121	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
122	IKKB_HUMAN	TF65_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
123	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	LCK_HUMAN	ZAP70_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
125	ABL1_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
126	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
127	LCK_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
128	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
129	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
130	IKKB_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD; NetPath; Robert H Newman (2013)
131	LCK_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
132	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
133	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
134	FYN_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
135	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
136	AKT1_HUMAN	MTOR_HUMAN	kinase -> substrate	RegPhos
137	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
138	KIT_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
139	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
140	AKT1_HUMAN	STAT6_HUMAN	kinase -> substrate	Robert H Newman (2013)
141	KPCI_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
142	ESR1_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
143	DDR2_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
144	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
145	LCK_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
146	EGFR_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
147	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
148	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
149	AKT1_HUMAN	TEAD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
150	PTPRC_HUMAN	JAK1_HUMAN	phosphatase -> substrate	HPRD
151	ABL1_HUMAN	JUN_HUMAN	kinase -> substrate	HPRD; RegPhos
152	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
153	IGF1R_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
154	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
155	AKT1_HUMAN	SOX9_HUMAN	kinase -> substrate	Robert H Newman (2013)
156	LYN_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
157	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
158	SHC1_HUMAN	ZAP70_HUMAN	kinase -> substrate	HPRD
159	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
160	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
161	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
162	LCK_HUMAN	VDR_HUMAN	kinase -> substrate	Robert H Newman (2013)
163	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
164	YES_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
165	RAF1_HUMAN	MP2K1_HUMAN	kinase -> substrate; other	RegPhos; Robert H Newman (2013); KEGG
166	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
167	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
168	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
169	M3K11_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
170	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
171	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
172	CDK1_HUMAN	CUX1_HUMAN	kinase -> substrate	RegPhos
173	MK07_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
174	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
175	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
176	KPCD_HUMAN	TWST1_HUMAN	kinase -> substrate	Robert H Newman (2013)
177	CDK1_HUMAN	HMGA1_HUMAN	kinase -> substrate	RegPhos
178	MK07_HUMAN	MEF2D_HUMAN	kinase -> substrate	HPRD
179	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
180	CDK5_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
181	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
182	KPCD_HUMAN	NF2L2_HUMAN	kinase -> substrate	HPRD
183	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
184	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
185	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
186	CDK1_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
187	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
188	CDK5_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
189	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
190	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
191	CDK1_HUMAN	E2F1_HUMAN	kinase -> substrate	RegPhos
192	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
193	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
194	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
195	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
196	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
197	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
198	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
199	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
200	RET_HUMAN	MK14_HUMAN	kinase -> substrate	HPRD; RegPhos
201	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
202	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
203	CDK1_HUMAN	HMGA2_HUMAN	kinase -> substrate	RegPhos
204	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
205	CDK5_HUMAN	MEF2D_HUMAN	kinase -> substrate	RegPhos
206	FOXO1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
207	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
208	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
209	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
210	AP2A_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
211	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
212	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
213	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
214	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
215	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
216	JAK1_HUMAN	STAT4_HUMAN	kinase -> substrate	RegPhos
217	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
218	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
219	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
220	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
221	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
222	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
223	MP2K7_HUMAN	M3K7_HUMAN	kinase -> substrate	KEGG
224	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
225	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
226	CDK7_HUMAN	PO2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
227	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
228	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
229	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
230	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
231	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
232	M3K7_HUMAN	NLK_HUMAN	kinase -> substrate	KEGG
233	M3K7_HUMAN	FUBP1_HUMAN	kinase -> substrate	Robert H Newman (2013)
234	NLK_HUMAN	LEF1_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network