Phosphorylation

You are querying signaling transduction network mediated by ADA2B_HUMAN in Lymphoma.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	DOPO_HUMAN	ADA2B_HUMAN	ligand -> receptor	HPMR
2	ADA2B_HUMAN	GNAI1_HUMAN	GPCR -> Gprotein	gpDB
3	ADA2B_HUMAN	GNAI2_HUMAN	GPCR -> Gprotein	gpDB
4	ADA2B_HUMAN	GNAI3_HUMAN	GPCR -> Gprotein	gpDB
5	ADA2B_HUMAN	GNAO_HUMAN	GPCR -> Gprotein	gpDB
6	GNAI1_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
7	GNAI2_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
8	GNAI3_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
9	GNAI1_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
10	GNAI3_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
11	GNAO_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
12	GNAI1_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
13	GNAO_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
14	GNAI2_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
15	GNAI3_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
16	GNAI2_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
17	RAC1_HUMAN	MK08_HUMAN	kinase -> substrate; other	KEGG
18	CSK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
19	SRC_HUMAN	AKT1_HUMAN	kinase -> substrate	RegPhos
20	SRC_HUMAN	FAK1_HUMAN	kinase -> substrate	RegPhos; NetPath
21	SRC_HUMAN	ABL1_HUMAN	kinase -> substrate	RegPhos
22	CSK_HUMAN	LCK_HUMAN	kinase -> substrate	HPRD; RegPhos
23	CSK_HUMAN	LYN_HUMAN	kinase -> substrate; other	HPRD; RegPhos; Robert H Newman (2013); KEGG
24	CSK_HUMAN	FGR_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
25	SRC_HUMAN	STAT3_HUMAN	kinase -> substrate	HPRD; RegPhos
26	SRC_HUMAN	STA5B_HUMAN	kinase -> substrate	HPRD; RegPhos
27	CSK_HUMAN	FYN_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
28	SRC_HUMAN	HNRPK_HUMAN	kinase -> substrate	RegPhos
29	SRC_HUMAN	PDPK1_HUMAN	kinase -> substrate	RegPhos
30	CSK_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
31	SRC_HUMAN	RHG35_HUMAN	kinase -> substrate	KEGG; HPRD; RegPhos
32	SRC_HUMAN	DDR2_HUMAN	kinase -> substrate	RegPhos
33	SRC_HUMAN	ESR1_HUMAN	kinase -> substrate	HPRD; RegPhos
34	CSK_HUMAN	ANDR_HUMAN	kinase -> substrate	RegPhos
35	SRC_HUMAN	IKKB_HUMAN	kinase -> substrate	NetPath
36	SRC_HUMAN	KIT_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
37	SRC_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
38	CSK_HUMAN	PTPRC_HUMAN	kinase -> substrate	Robert H Newman (2013)
39	CSK_HUMAN	YES_HUMAN	kinase -> substrate	Robert H Newman (2013)
40	SRC_HUMAN	IKKA_HUMAN	kinase -> substrate	NetPath
41	SRC_HUMAN	SHC1_HUMAN	kinase -> substrate	RegPhos
42	CSK_HUMAN	MK15_HUMAN	kinase -> substrate	RegPhos
43	SRC_HUMAN	EGFR_HUMAN	kinase -> substrate	RegPhos
44	SRC_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos
45	SRC_HUMAN	KPCI_HUMAN	kinase -> substrate	RegPhos
46	SRC_HUMAN	RAF1_HUMAN	kinase -> substrate	HPRD; RegPhos
47	CSK_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
48	SRC_HUMAN	IGF1R_HUMAN	kinase -> substrate	RegPhos
49	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
50	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
51	AKT1_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos
52	FAK1_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
53	ABL1_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
54	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
55	LCK_HUMAN	ZAP70_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
56	LYN_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
57	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
58	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
59	FAK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
60	STAT3_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
61	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
62	STAT3_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
63	FYN_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
64	LYN_HUMAN	CDK1_HUMAN	kinase -> substrate	HPRD; RegPhos
65	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
66	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
67	LCK_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
68	AKT1_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
69	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
70	PDPK1_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
71	AKT1_HUMAN	TEAD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
72	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
73	ETS1_HUMAN	NFKB1_HUMAN	TF -> target gene	TRANSFAC
74	LYN_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
75	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
76	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
77	AKT1_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos
78	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
79	DDR2_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
80	ESR1_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
81	PDPK1_HUMAN	MP2K1_HUMAN	kinase -> substrate	RegPhos
82	FYN_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
83	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
84	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
85	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
86	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
87	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
88	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
89	AKT1_HUMAN	SOX9_HUMAN	kinase -> substrate	Robert H Newman (2013)
90	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
91	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
92	IKKB_HUMAN	TF65_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
93	KIT_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
94	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
95	LCK_HUMAN	VDR_HUMAN	kinase -> substrate	Robert H Newman (2013)
96	PTPRC_HUMAN	JAK1_HUMAN	phosphatase -> substrate	HPRD
97	YES_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
98	AKT1_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
99	IKKA_HUMAN	NFKB1_HUMAN	kinase -> substrate; other	HPRD; NetPath; KEGG
100	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
101	PDPK1_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD; RegPhos
102	AKT1_HUMAN	MTOR_HUMAN	kinase -> substrate	RegPhos
103	SHC1_HUMAN	ZAP70_HUMAN	kinase -> substrate	HPRD
104	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
105	AKT1_HUMAN	GSK3B_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
106	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
107	MK15_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
108	EGFR_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
109	PDPK1_HUMAN	KPCD_HUMAN	kinase -> substrate	HPRD; RegPhos
110	AKT1_HUMAN	FOXO1_HUMAN	kinase -> substrate	RegPhos; NetPath
111	PDPK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
112	KPCI_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
113	PDPK1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
114	AKT1_HUMAN	M3K11_HUMAN	kinase -> substrate	HPRD; RegPhos
115	IKKA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD; NetPath
116	AKT1_HUMAN	EP300_HUMAN	kinase -> substrate	HPRD; RegPhos
117	AKT1_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD; RegPhos
118	STAT3_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
119	PDPK1_HUMAN	PKN1_HUMAN	kinase -> substrate	RegPhos
120	LYN_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
121	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
122	FYN_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
123	LCK_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
124	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
125	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
126	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
127	RAF1_HUMAN	MP2K1_HUMAN	kinase -> substrate; other	RegPhos; Robert H Newman (2013); KEGG
128	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
129	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
130	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
131	IKKB_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD; NetPath; Robert H Newman (2013)
132	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
133	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
134	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
135	AKT1_HUMAN	GATA2_HUMAN	kinase -> substrate	HPRD
136	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
137	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
138	AKT1_HUMAN	THA_HUMAN	kinase -> substrate	Robert H Newman (2013)
139	ABL1_HUMAN	P73_HUMAN	kinase -> substrate	HPRD; RegPhos
140	AKT1_HUMAN	GSK3A_HUMAN	kinase -> substrate	NetPath
141	AKT1_HUMAN	GATA1_HUMAN	kinase -> substrate	HPRD; RegPhos
142	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
143	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
144	ETS1_HUMAN	AP2A_HUMAN	TF -> target gene	TRANSFAC
145	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
146	ABL1_HUMAN	JUN_HUMAN	kinase -> substrate	HPRD; RegPhos
147	RHG35_HUMAN	GCR_HUMAN	TF -> target gene	TRANSFAC
148	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
149	ESR1_HUMAN	PRGR_HUMAN	TF -> target gene	TRANSFAC
150	DDR2_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
151	RAF1_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
152	FYN_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
153	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
154	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
155	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
156	YES_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
157	YES_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
158	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
159	KPCI_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
160	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
161	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
162	AKT1_HUMAN	STAT6_HUMAN	kinase -> substrate	Robert H Newman (2013)
163	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
164	IGF1R_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
165	IKKA_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
166	LCK_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
167	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
168	CDK5_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
169	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
170	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
171	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
172	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
173	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
174	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
175	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
176	CDK5_HUMAN	MEF2D_HUMAN	kinase -> substrate	RegPhos
177	CDK1_HUMAN	E2F1_HUMAN	kinase -> substrate	RegPhos
178	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
179	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
180	KPCD_HUMAN	TWST1_HUMAN	kinase -> substrate	Robert H Newman (2013)
181	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
182	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
183	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
184	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
185	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
186	CDK1_HUMAN	CUX1_HUMAN	kinase -> substrate	RegPhos
187	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
188	CDK1_HUMAN	HMGA1_HUMAN	kinase -> substrate	RegPhos
189	MK07_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
190	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
191	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
192	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
193	JAK1_HUMAN	STAT4_HUMAN	kinase -> substrate	RegPhos
194	CDK5_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
195	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
196	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
197	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
198	RET_HUMAN	MK14_HUMAN	kinase -> substrate	HPRD; RegPhos
199	FOXO1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
200	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
201	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
202	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
203	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
204	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
205	M3K11_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
206	KPCD_HUMAN	NF2L2_HUMAN	kinase -> substrate	HPRD
207	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
208	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
209	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
210	CDK1_HUMAN	HMGA2_HUMAN	kinase -> substrate	RegPhos
211	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
212	MK07_HUMAN	MEF2D_HUMAN	kinase -> substrate	HPRD
213	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
214	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
215	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
216	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
217	AP2A_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
218	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
219	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
220	CDK1_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
221	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
222	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
223	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
224	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
225	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
226	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
227	MP2K7_HUMAN	M3K7_HUMAN	kinase -> substrate	KEGG
228	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
229	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
230	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
231	CDK7_HUMAN	PO2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
232	M3K7_HUMAN	NLK_HUMAN	kinase -> substrate	KEGG
233	M3K7_HUMAN	FUBP1_HUMAN	kinase -> substrate	Robert H Newman (2013)
234	NLK_HUMAN	LEF1_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network