Phosphorylation

You are querying signaling transduction network mediated by 5HT5A_HUMAN in Lymphoma.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	TPH1_HUMAN	5HT5A_HUMAN	ligand -> receptor	HPMR
2	5HT5A_HUMAN	GNAI2_HUMAN	GPCR -> Gprotein	gpDB
3	5HT5A_HUMAN	GNAI3_HUMAN	GPCR -> Gprotein	gpDB
4	5HT5A_HUMAN	GNAI1_HUMAN	GPCR -> Gprotein	gpDB
5	5HT5A_HUMAN	GNAO_HUMAN	GPCR -> Gprotein	gpDB
6	GNAI2_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
7	GNAI3_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
8	GNAI1_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
9	GNAI1_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
10	GNAO_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
11	GNAI2_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
12	GNAI3_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
13	GNAO_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
14	GNAI2_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
15	GNAI3_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
16	GNAI1_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
17	RAC1_HUMAN	MK08_HUMAN	kinase -> substrate; other	KEGG
18	CSK_HUMAN	LYN_HUMAN	kinase -> substrate; other	HPRD; RegPhos; Robert H Newman (2013); KEGG
19	SRC_HUMAN	PDPK1_HUMAN	kinase -> substrate	RegPhos
20	SRC_HUMAN	AKT1_HUMAN	kinase -> substrate	RegPhos
21	CSK_HUMAN	FYN_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
22	CSK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
23	SRC_HUMAN	RHG35_HUMAN	kinase -> substrate	KEGG; HPRD; RegPhos
24	SRC_HUMAN	HNRPK_HUMAN	kinase -> substrate	RegPhos
25	CSK_HUMAN	YES_HUMAN	kinase -> substrate	Robert H Newman (2013)
26	SRC_HUMAN	IKKA_HUMAN	kinase -> substrate	NetPath
27	SRC_HUMAN	ESR1_HUMAN	kinase -> substrate	HPRD; RegPhos
28	SRC_HUMAN	ABL1_HUMAN	kinase -> substrate	RegPhos
29	SRC_HUMAN	IGF1R_HUMAN	kinase -> substrate	RegPhos
30	SRC_HUMAN	RAF1_HUMAN	kinase -> substrate	HPRD; RegPhos
31	CSK_HUMAN	FGR_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
32	CSK_HUMAN	MK15_HUMAN	kinase -> substrate	RegPhos
33	SRC_HUMAN	SHC1_HUMAN	kinase -> substrate	RegPhos
34	CSK_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
35	SRC_HUMAN	DDR2_HUMAN	kinase -> substrate	RegPhos
36	SRC_HUMAN	KIT_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
37	SRC_HUMAN	STAT3_HUMAN	kinase -> substrate	HPRD; RegPhos
38	CSK_HUMAN	LCK_HUMAN	kinase -> substrate	HPRD; RegPhos
39	SRC_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
40	SRC_HUMAN	IKKB_HUMAN	kinase -> substrate	NetPath
41	SRC_HUMAN	FAK1_HUMAN	kinase -> substrate	RegPhos; NetPath
42	SRC_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos
43	SRC_HUMAN	STA5B_HUMAN	kinase -> substrate	HPRD; RegPhos
44	CSK_HUMAN	PTPRC_HUMAN	kinase -> substrate	Robert H Newman (2013)
45	CSK_HUMAN	ANDR_HUMAN	kinase -> substrate	RegPhos
46	SRC_HUMAN	EGFR_HUMAN	kinase -> substrate	RegPhos
47	CSK_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
48	SRC_HUMAN	KPCI_HUMAN	kinase -> substrate	RegPhos
49	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
50	LYN_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
51	PDPK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
52	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
53	AKT1_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD; RegPhos
54	FYN_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
55	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
56	AKT1_HUMAN	FOXO1_HUMAN	kinase -> substrate	RegPhos; NetPath
57	LYN_HUMAN	CDK1_HUMAN	kinase -> substrate	HPRD; RegPhos
58	AKT1_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
59	RHG35_HUMAN	GCR_HUMAN	TF -> target gene	TRANSFAC
60	PDPK1_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
62	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
63	YES_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
64	FYN_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
65	IKKA_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
66	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
67	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
68	PDPK1_HUMAN	PKN1_HUMAN	kinase -> substrate	RegPhos
69	ABL1_HUMAN	P73_HUMAN	kinase -> substrate	HPRD; RegPhos
70	IGF1R_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
71	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
72	RAF1_HUMAN	MP2K1_HUMAN	kinase -> substrate; other	RegPhos; Robert H Newman (2013); KEGG
73	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
74	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
75	MK15_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
76	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
77	SHC1_HUMAN	ZAP70_HUMAN	kinase -> substrate	HPRD
78	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
79	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
80	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
81	PDPK1_HUMAN	MP2K1_HUMAN	kinase -> substrate	RegPhos
82	DDR2_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
83	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
84	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
85	AKT1_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos
86	PDPK1_HUMAN	KPCD_HUMAN	kinase -> substrate	HPRD; RegPhos
87	ETS1_HUMAN	AP2A_HUMAN	TF -> target gene	TRANSFAC
88	LYN_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
89	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
90	KIT_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
91	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
92	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
93	STAT3_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
94	FYN_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
95	RAF1_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
96	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
97	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
98	AKT1_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos
99	ABL1_HUMAN	JUN_HUMAN	kinase -> substrate	HPRD; RegPhos
100	AKT1_HUMAN	GATA2_HUMAN	kinase -> substrate	HPRD
101	STAT3_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
102	PDPK1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
103	DDR2_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
104	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
105	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
106	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
107	YES_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
108	LCK_HUMAN	VDR_HUMAN	kinase -> substrate	Robert H Newman (2013)
109	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
110	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
111	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
112	STAT3_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
113	AKT1_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
114	AKT1_HUMAN	GSK3B_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
115	AKT1_HUMAN	MTOR_HUMAN	kinase -> substrate	RegPhos
116	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
117	IKKB_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD; NetPath; Robert H Newman (2013)
118	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
119	LCK_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
120	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
121	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
122	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
123	FAK1_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	ETS1_HUMAN	NFKB1_HUMAN	TF -> target gene	TRANSFAC
125	IKKA_HUMAN	NFKB1_HUMAN	kinase -> substrate; other	HPRD; NetPath; KEGG
126	LCK_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
127	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
128	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
129	PDPK1_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD; RegPhos
130	ABL1_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
131	ESR1_HUMAN	PRGR_HUMAN	TF -> target gene	TRANSFAC
132	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
133	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
134	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
135	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
136	AKT1_HUMAN	M3K11_HUMAN	kinase -> substrate	HPRD; RegPhos
137	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
138	FYN_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
139	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
140	IKKA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD; NetPath
141	LCK_HUMAN	ZAP70_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
142	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
143	AKT1_HUMAN	THA_HUMAN	kinase -> substrate	Robert H Newman (2013)
144	PTPRC_HUMAN	JAK1_HUMAN	phosphatase -> substrate	HPRD
145	AKT1_HUMAN	TEAD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
146	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
147	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
148	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
149	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
150	AKT1_HUMAN	GSK3A_HUMAN	kinase -> substrate	NetPath
151	FAK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
152	LYN_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
153	AKT1_HUMAN	SOX9_HUMAN	kinase -> substrate	Robert H Newman (2013)
154	ESR1_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
155	YES_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
156	EGFR_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
157	AKT1_HUMAN	GATA1_HUMAN	kinase -> substrate	HPRD; RegPhos
158	KPCI_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
159	LCK_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
160	AKT1_HUMAN	STAT6_HUMAN	kinase -> substrate	Robert H Newman (2013)
161	IKKB_HUMAN	TF65_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
162	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
163	AKT1_HUMAN	EP300_HUMAN	kinase -> substrate	HPRD; RegPhos
164	KPCI_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
165	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
166	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
167	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
168	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
169	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
170	CDK1_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
171	KPCD_HUMAN	NF2L2_HUMAN	kinase -> substrate	HPRD
172	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
173	CDK1_HUMAN	HMGA2_HUMAN	kinase -> substrate	RegPhos
174	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
175	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
176	CDK5_HUMAN	MEF2D_HUMAN	kinase -> substrate	RegPhos
177	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
178	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
179	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
180	RET_HUMAN	MK14_HUMAN	kinase -> substrate	HPRD; RegPhos
181	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
182	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
183	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
184	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
185	KPCD_HUMAN	TWST1_HUMAN	kinase -> substrate	Robert H Newman (2013)
186	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
187	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
188	MK07_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
189	AP2A_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
190	CDK1_HUMAN	HMGA1_HUMAN	kinase -> substrate	RegPhos
191	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
192	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
193	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
194	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
195	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
196	CDK5_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
197	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
198	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
199	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
200	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
201	CDK5_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
202	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
203	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
204	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
205	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
206	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
207	M3K11_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
208	MK07_HUMAN	MEF2D_HUMAN	kinase -> substrate	HPRD
209	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
210	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
211	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
212	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
213	JAK1_HUMAN	STAT4_HUMAN	kinase -> substrate	RegPhos
214	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
215	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
216	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
217	CDK1_HUMAN	CUX1_HUMAN	kinase -> substrate	RegPhos
218	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
219	FOXO1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
220	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
221	CDK1_HUMAN	E2F1_HUMAN	kinase -> substrate	RegPhos
222	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
223	CDK7_HUMAN	PO2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
224	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
225	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
226	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
227	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
228	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
229	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
230	MP2K7_HUMAN	M3K7_HUMAN	kinase -> substrate	KEGG
231	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
232	M3K7_HUMAN	FUBP1_HUMAN	kinase -> substrate	Robert H Newman (2013)
233	M3K7_HUMAN	NLK_HUMAN	kinase -> substrate	KEGG
234	NLK_HUMAN	LEF1_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network