Phosphorylation

You are querying signaling transduction network mediated by ACM2_HUMAN in Lymphoma.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	CLAT_HUMAN	ACM2_HUMAN	ligand -> receptor	HPMR
2	ACM2_HUMAN	GNAI3_HUMAN	GPCR -> Gprotein	gpDB
3	ACM2_HUMAN	GNAO_HUMAN	GPCR -> Gprotein	gpDB
4	ACM2_HUMAN	GNAI1_HUMAN	GPCR -> Gprotein	gpDB
5	ACM2_HUMAN	GNAI2_HUMAN	GPCR -> Gprotein	gpDB
6	GNAI3_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
7	GNAO_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
8	GNAI1_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
9	GNAI1_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
10	GNAI2_HUMAN	CSK_HUMAN	Gprotein -> effector	gpDB
11	GNAI2_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
12	GNAI1_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
13	GNAO_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
14	GNAI3_HUMAN	SRC_HUMAN	Gprotein -> effector	gpDB
15	GNAI3_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
16	GNAI2_HUMAN	RAC1_HUMAN	Gprotein -> effector	gpDB
17	CSK_HUMAN	YES_HUMAN	kinase -> substrate	Robert H Newman (2013)
18	CSK_HUMAN	FGR_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
19	CSK_HUMAN	LYN_HUMAN	kinase -> substrate; other	HPRD; RegPhos; Robert H Newman (2013); KEGG
20	SRC_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
21	SRC_HUMAN	AKT1_HUMAN	kinase -> substrate	RegPhos
22	CSK_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
23	SRC_HUMAN	STAT3_HUMAN	kinase -> substrate	HPRD; RegPhos
24	RAC1_HUMAN	MK08_HUMAN	kinase -> substrate; other	KEGG
25	CSK_HUMAN	LCK_HUMAN	kinase -> substrate	HPRD; RegPhos
26	SRC_HUMAN	PDPK1_HUMAN	kinase -> substrate	RegPhos
27	CSK_HUMAN	MK15_HUMAN	kinase -> substrate	RegPhos
28	SRC_HUMAN	STA5B_HUMAN	kinase -> substrate	HPRD; RegPhos
29	SRC_HUMAN	IKKB_HUMAN	kinase -> substrate	NetPath
30	SRC_HUMAN	FAK1_HUMAN	kinase -> substrate	RegPhos; NetPath
31	SRC_HUMAN	SHC1_HUMAN	kinase -> substrate	RegPhos
32	CSK_HUMAN	FYN_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
33	SRC_HUMAN	ESR1_HUMAN	kinase -> substrate	HPRD; RegPhos
34	SRC_HUMAN	ABL1_HUMAN	kinase -> substrate	RegPhos
35	CSK_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	CSK_HUMAN	PTPRC_HUMAN	kinase -> substrate	Robert H Newman (2013)
37	SRC_HUMAN	DDR2_HUMAN	kinase -> substrate	RegPhos
38	SRC_HUMAN	HNRPK_HUMAN	kinase -> substrate	RegPhos
39	SRC_HUMAN	IGF1R_HUMAN	kinase -> substrate	RegPhos
40	CSK_HUMAN	ANDR_HUMAN	kinase -> substrate	RegPhos
41	SRC_HUMAN	RAF1_HUMAN	kinase -> substrate	HPRD; RegPhos
42	SRC_HUMAN	EGFR_HUMAN	kinase -> substrate	RegPhos
43	SRC_HUMAN	KPCI_HUMAN	kinase -> substrate	RegPhos
44	SRC_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos
45	SRC_HUMAN	RHG35_HUMAN	kinase -> substrate	KEGG; HPRD; RegPhos
46	SRC_HUMAN	IKKA_HUMAN	kinase -> substrate	NetPath
47	CSK_HUMAN	CTNB1_HUMAN	kinase -> substrate	RegPhos
48	SRC_HUMAN	KIT_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
49	YES_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
50	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
51	LYN_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
52	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
53	AKT1_HUMAN	SOX9_HUMAN	kinase -> substrate	Robert H Newman (2013)
54	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
55	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
56	LYN_HUMAN	MK03_HUMAN	kinase -> substrate	NetPath
57	STAT3_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
58	AKT1_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD; RegPhos
59	MK08_HUMAN	NFAC4_HUMAN	kinase -> substrate	KEGG
60	LCK_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	PDPK1_HUMAN	KPCD_HUMAN	kinase -> substrate	HPRD; RegPhos
62	MK15_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
63	KPCA_HUMAN	GSK3B_HUMAN	kinase -> substrate	KEGG; HPRD
64	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
65	IKKB_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD; NetPath; Robert H Newman (2013)
66	LCK_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
67	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
68	FAK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
69	AKT1_HUMAN	THA_HUMAN	kinase -> substrate	Robert H Newman (2013)
70	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
71	SHC1_HUMAN	ZAP70_HUMAN	kinase -> substrate	HPRD
72	FYN_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
73	AKT1_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
74	PDPK1_HUMAN	PKN1_HUMAN	kinase -> substrate	RegPhos
75	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
76	MK08_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD; RegPhos
77	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
78	YES_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
79	ABL1_HUMAN	JUN_HUMAN	kinase -> substrate	HPRD; RegPhos
80	ETS1_HUMAN	NFKB1_HUMAN	TF -> target gene	TRANSFAC
81	ABL1_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
82	LCK_HUMAN	VDR_HUMAN	kinase -> substrate	Robert H Newman (2013)
83	PTPRC_HUMAN	JAK1_HUMAN	phosphatase -> substrate	HPRD
84	DDR2_HUMAN	RET_HUMAN	kinase -> substrate	Robert H Newman (2013)
85	FYN_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
86	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
87	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
88	LCK_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
89	MK08_HUMAN	JUN_HUMAN	kinase -> substrate; other	NetPath; Robert H Newman (2013); KEGG
90	DDR2_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
91	ABL1_HUMAN	P73_HUMAN	kinase -> substrate	HPRD; RegPhos
92	IGF1R_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
93	KPCA_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
94	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
95	LYN_HUMAN	CDK1_HUMAN	kinase -> substrate	HPRD; RegPhos
96	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
97	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
98	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
99	MK08_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos
100	FAK1_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
101	MK08_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
102	KPCA_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
103	AKT1_HUMAN	EP300_HUMAN	kinase -> substrate	HPRD; RegPhos
104	AKT1_HUMAN	GSK3A_HUMAN	kinase -> substrate	NetPath
105	FYN_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
106	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
107	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
108	MK08_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
109	AKT1_HUMAN	M3K11_HUMAN	kinase -> substrate	HPRD; RegPhos
110	LYN_HUMAN	KPCD_HUMAN	kinase -> substrate	RegPhos
111	MK08_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
112	ESR1_HUMAN	PRGR_HUMAN	TF -> target gene	TRANSFAC
113	RAF1_HUMAN	MP2K1_HUMAN	kinase -> substrate; other	RegPhos; Robert H Newman (2013); KEGG
114	FYN_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
115	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
116	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
117	AKT1_HUMAN	FOXO1_HUMAN	kinase -> substrate	RegPhos; NetPath
118	EGFR_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
119	MK08_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
120	LCK_HUMAN	ZAP70_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
121	MK08_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
122	AKT1_HUMAN	STAT6_HUMAN	kinase -> substrate	Robert H Newman (2013)
123	AKT1_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos
124	KPCI_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
125	AKT1_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos
126	AKT1_HUMAN	GSK3B_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
127	AKT1_HUMAN	GATA2_HUMAN	kinase -> substrate	HPRD
128	PDPK1_HUMAN	MP2K1_HUMAN	kinase -> substrate	RegPhos
129	AKT1_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
130	STAT3_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
131	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
132	ETS1_HUMAN	AP2A_HUMAN	TF -> target gene	TRANSFAC
133	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
134	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
135	RAF1_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
136	PDPK1_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
137	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
138	STAT3_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
139	RHG35_HUMAN	GCR_HUMAN	TF -> target gene	TRANSFAC
140	AKT1_HUMAN	TEAD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
141	IKKA_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
142	MK08_HUMAN	SMAD4_HUMAN	kinase -> substrate	Robert H Newman (2013)
143	FGR_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
144	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
145	KPCI_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
146	MK08_HUMAN	MITF_HUMAN	kinase -> substrate	Robert H Newman (2013)
147	PDPK1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
148	MK08_HUMAN	PPARA_HUMAN	kinase -> substrate	Robert H Newman (2013)
149	KPCA_HUMAN	EP300_HUMAN	kinase -> substrate	Robert H Newman (2013)
150	IKKA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD; NetPath
151	ESR1_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
152	FGR_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
153	AKT1_HUMAN	GATA1_HUMAN	kinase -> substrate	HPRD; RegPhos
154	AKT1_HUMAN	MTOR_HUMAN	kinase -> substrate	RegPhos
155	PDPK1_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD; RegPhos
156	KIT_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
157	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
158	MK08_HUMAN	FOS_HUMAN	kinase -> substrate	KEGG
159	FGR_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
160	IKKB_HUMAN	TF65_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
161	YES_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
162	IKKA_HUMAN	NFKB1_HUMAN	kinase -> substrate; other	HPRD; NetPath; KEGG
163	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
164	PDPK1_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
165	GTF2I_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
166	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
167	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
168	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
169	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
170	MK03_HUMAN	MAZ_HUMAN	kinase -> substrate	Robert H Newman (2013)
171	CSK21_HUMAN	MYF5_HUMAN	kinase -> substrate	HPRD
172	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
173	KPCD_HUMAN	TWST1_HUMAN	kinase -> substrate	Robert H Newman (2013)
174	RET_HUMAN	MK14_HUMAN	kinase -> substrate	HPRD; RegPhos
175	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
176	KPCD_HUMAN	NF2L2_HUMAN	kinase -> substrate	HPRD
177	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
178	CDK5_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
179	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
180	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
181	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
182	CSK21_HUMAN	MEF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
183	JAK1_HUMAN	STAT4_HUMAN	kinase -> substrate	RegPhos
184	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
185	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
186	CDK5_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
187	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
188	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
189	CDK5_HUMAN	MEF2D_HUMAN	kinase -> substrate	RegPhos
190	CDK1_HUMAN	CUX1_HUMAN	kinase -> substrate	RegPhos
191	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
192	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
193	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
194	CDK1_HUMAN	HMGA2_HUMAN	kinase -> substrate	RegPhos
195	MK07_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
196	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
197	M3K11_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
198	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
199	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
200	CSK21_HUMAN	HMGA1_HUMAN	kinase -> substrate	HPRD
201	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
202	FOXO1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
203	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
204	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
205	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
206	STK11_HUMAN	SIK3_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
207	STK11_HUMAN	SIK2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
208	DYR1B_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
209	AP2A_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
210	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
211	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
212	CSK21_HUMAN	TF7L2_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
213	CDK1_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
214	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
215	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
216	CDK1_HUMAN	HMGA1_HUMAN	kinase -> substrate	RegPhos
217	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
218	CDK1_HUMAN	E2F1_HUMAN	kinase -> substrate	RegPhos
219	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
220	STK11_HUMAN	SIK1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
221	MK07_HUMAN	MEF2D_HUMAN	kinase -> substrate	HPRD
222	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
223	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
224	MP2K7_HUMAN	M3K7_HUMAN	kinase -> substrate	KEGG
225	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
226	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
227	SIK3_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
228	SIK2_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
229	CDK7_HUMAN	PO2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
230	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
231	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
232	M3K7_HUMAN	FUBP1_HUMAN	kinase -> substrate	Robert H Newman (2013)
233	M3K7_HUMAN	NLK_HUMAN	kinase -> substrate	KEGG
234	NLK_HUMAN	LEF1_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network