Phosphorylation

You are querying signaling transduction network mediated by BMR1B_HUMAN in Lung Cancer.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	BMP4_HUMAN	BMR1B_HUMAN	ligand -> receptor	HPMR
2	BMP15_HUMAN	BMR1B_HUMAN	ligand -> receptor	HPMR
3	BMP7_HUMAN	BMR1B_HUMAN	ligand -> receptor	HPMR
4	BMP2_HUMAN	BMR1B_HUMAN	ligand -> receptor	HPMR
5	BMR1B_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
6	BMR1B_HUMAN	RIPK3_HUMAN	kinase -> substrate	Robert H Newman (2013)
7	BMR1B_HUMAN	GRK5_HUMAN	kinase -> substrate	Robert H Newman (2013)
8	BMR1B_HUMAN	NFAC4_HUMAN	kinase -> substrate	Robert H Newman (2013)
9	BMR1B_HUMAN	SMAD3_HUMAN	kinase -> substrate	Robert H Newman (2013)
10	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
11	RIPK3_HUMAN	MK01_HUMAN	kinase -> substrate	Robert H Newman (2013)
12	RIPK3_HUMAN	RIPK1_HUMAN	kinase -> substrate	NetPath
13	KKCC1_HUMAN	AKT1_HUMAN	kinase -> substrate	HPRD
14	GRK5_HUMAN	ENOA_HUMAN	kinase -> substrate	Robert H Newman (2013)
15	RIPK3_HUMAN	E2AK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
16	KKCC1_HUMAN	KCC4_HUMAN	kinase -> substrate	HPRD
17	GRK5_HUMAN	KCC2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
18	KKCC1_HUMAN	CLK1_HUMAN	kinase -> substrate	Robert H Newman (2013)
19	SMAD3_HUMAN	JUN_HUMAN	TF -> target gene	TRANSFAC
20	KKCC1_HUMAN	PPP5_HUMAN	kinase -> substrate	Robert H Newman (2013)
21	GRK5_HUMAN	BMX_HUMAN	kinase -> substrate	Robert H Newman (2013)
22	MK01_HUMAN	STA5A_HUMAN	kinase -> substrate	Robert H Newman (2013)
23	RIPK1_HUMAN	M3K1_HUMAN	kinase -> substrate	NetPath
24	AKT1_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
25	MK01_HUMAN	PKN1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
26	MK01_HUMAN	TFE2_HUMAN	kinase -> substrate	HPRD; NetPath
27	AKT1_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
28	AKT1_HUMAN	IRAK1_HUMAN	kinase -> substrate	RegPhos
29	MK01_HUMAN	SP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
30	MK01_HUMAN	ANDR_HUMAN	kinase -> substrate	HPRD
31	AKT1_HUMAN	SOX9_HUMAN	kinase -> substrate	Robert H Newman (2013)
32	ENOA_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
33	AKT1_HUMAN	THA_HUMAN	kinase -> substrate	Robert H Newman (2013)
34	AKT1_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
35	AKT1_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	E2AK2_HUMAN	PLK1_HUMAN	kinase -> substrate	Robert H Newman (2013)
37	MK01_HUMAN	GCR_HUMAN	kinase -> substrate	HPRD
38	MK01_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD
39	AKT1_HUMAN	CHK1_HUMAN	kinase -> substrate	HPRD; RegPhos
40	MK01_HUMAN	LCK_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
41	MK01_HUMAN	SRBP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
42	E2AK2_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
43	MK01_HUMAN	MYB_HUMAN	kinase -> substrate	HPRD
44	E2AK2_HUMAN	P53_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
45	MK01_HUMAN	MITF_HUMAN	kinase -> substrate	NetPath
46	AKT1_HUMAN	GATA1_HUMAN	kinase -> substrate	HPRD; RegPhos
47	MK01_HUMAN	ESR1_HUMAN	kinase -> substrate	HPRD
48	KCC4_HUMAN	CREB1_HUMAN	kinase -> substrate	Robert H Newman (2013)
49	MK01_HUMAN	RXRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
50	KCC4_HUMAN	CEBPB_HUMAN	kinase -> substrate	Robert H Newman (2013)
51	MK01_HUMAN	SOS1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
52	MK01_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
53	MK01_HUMAN	P53_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
54	MK01_HUMAN	MYC_HUMAN	kinase -> substrate	KEGG; Robert H Newman (2013)
55	AKT1_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos
56	AKT1_HUMAN	STAT6_HUMAN	kinase -> substrate	Robert H Newman (2013)
57	KCC2A_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD
58	MK01_HUMAN	FOS_HUMAN	kinase -> substrate; other	KEGG
59	AKT1_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
60	MK01_HUMAN	CEBPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	AKT1_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
62	KCC2A_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
63	CLK1_HUMAN	SRPK1_HUMAN	kinase -> substrate	Robert H Newman (2013)
64	JUN_HUMAN	P53_HUMAN	TF -> target gene	TRANSFAC
65	AKT1_HUMAN	EP300_HUMAN	kinase -> substrate	HPRD; RegPhos
66	MK01_HUMAN	ELK1_HUMAN	kinase -> substrate	NetPath
67	MK01_HUMAN	CEBPB_HUMAN	kinase -> substrate	HPRD
68	MK01_HUMAN	PPARA_HUMAN	kinase -> substrate	HPRD
69	AKT1_HUMAN	ANDR_HUMAN	kinase -> substrate	RegPhos; NetPath
70	KCC2A_HUMAN	SRF_HUMAN	kinase -> substrate	HPRD
71	AKT1_HUMAN	CREB1_HUMAN	kinase -> substrate	HPRD; RegPhos
72	AKT1_HUMAN	M3K11_HUMAN	kinase -> substrate	HPRD; RegPhos
73	AKT1_HUMAN	NR4A1_HUMAN	kinase -> substrate	HPRD; RegPhos
74	MK01_HUMAN	BCL6_HUMAN	kinase -> substrate	NetPath
75	KCC2A_HUMAN	ETS1_HUMAN	kinase -> substrate	HPRD
76	AKT1_HUMAN	FOXO1_HUMAN	kinase -> substrate	RegPhos; NetPath
77	AKT1_HUMAN	MTOR_HUMAN	kinase -> substrate	RegPhos
78	MK01_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
79	MK01_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
80	KCC4_HUMAN	HSF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
81	AKT1_HUMAN	TEAD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
82	MK01_HUMAN	SRBP2_HUMAN	kinase -> substrate	Robert H Newman (2013)
83	JUN_HUMAN	MLTK_HUMAN	TF -> target gene	TRANSFAC
84	MK01_HUMAN	THB_HUMAN	kinase -> substrate	Robert H Newman (2013)
85	MK01_HUMAN	STAT3_HUMAN	kinase -> substrate	HPRD; NetPath
86	AKT1_HUMAN	ESR1_HUMAN	kinase -> substrate	HPRD; RegPhos
87	E2AK2_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
88	MK01_HUMAN	STK16_HUMAN	kinase -> substrate	Robert H Newman (2013)
89	AKT1_HUMAN	GATA2_HUMAN	kinase -> substrate	HPRD
90	MK01_HUMAN	KS6A5_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
91	KCC2A_HUMAN	EGFR_HUMAN	kinase -> substrate	HPRD
92	KCC4_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
93	MK01_HUMAN	PRGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
94	CLK1_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
95	KCC2A_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
96	MK01_HUMAN	GSK3B_HUMAN	kinase -> substrate	Robert H Newman (2013)
97	MK01_HUMAN	STF1_HUMAN	kinase -> substrate	HPRD
98	MK01_HUMAN	MP2K1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
99	AKT1_HUMAN	IKKA_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
100	PPP5_HUMAN	M3K5_HUMAN	phosphatase -> substrate	HPRD; KEGG
101	MK01_HUMAN	EGFR_HUMAN	kinase -> substrate	Robert H Newman (2013)
102	AKT1_HUMAN	M3K5_HUMAN	kinase -> substrate	HPRD; RegPhos
103	JUN_HUMAN	ATF3_HUMAN	TF -> target gene	TRANSFAC
104	MK01_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
105	AKT1_HUMAN	RAGE_HUMAN	kinase -> substrate	Robert H Newman (2013)
106	BMX_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
107	AKT1_HUMAN	PTN1_HUMAN	kinase -> substrate	HPRD; RegPhos
108	MK01_HUMAN	PTPRR_HUMAN	kinase -> substrate	HPRD
109	MK01_HUMAN	KS6A1_HUMAN	kinase -> substrate	HPRD
110	MK01_HUMAN	SOX10_HUMAN	kinase -> substrate	Robert H Newman (2013)
111	AKT1_HUMAN	GSK3B_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath
112	CLK1_HUMAN	PTN1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
113	STA5A_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
114	M3K1_HUMAN	MP2K7_HUMAN	kinase -> substrate	RegPhos
115	KPCD_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD
116	PKN1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
117	ETS1_HUMAN	AP2A_HUMAN	TF -> target gene	TRANSFAC
118	IRAK1_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
119	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
120	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
121	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
122	PLK1_HUMAN	CDK1_HUMAN	kinase -> substrate; phosphatase -> substrate	KEGG
123	GCR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
124	SP1_HUMAN	RARA_HUMAN	TF -> target gene	TRANSFAC
125	CHK1_HUMAN	CDK1_HUMAN	kinase -> substrate	KEGG
126	LCK_HUMAN	VDR_HUMAN	kinase -> substrate	Robert H Newman (2013)
127	SP1_HUMAN	CDK2_HUMAN	TF -> target gene	TRANSFAC
128	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
129	MYB_HUMAN	CDK1_HUMAN	TF -> target gene	TRANSFAC
130	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
131	SP1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
132	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
133	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
134	SP1_HUMAN	AP2C_HUMAN	TF -> target gene	TRANSFAC
135	SP1_HUMAN	TGFR2_HUMAN	TF -> target gene	TRANSFAC
136	NR4A1_HUMAN	E2F1_HUMAN	TF -> target gene	TRANSFAC
137	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
138	SP1_HUMAN	REL_HUMAN	TF -> target gene	TRANSFAC
139	MK08_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD; RegPhos
140	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
141	PLK1_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
142	SRPK1_HUMAN	PRDM1_HUMAN	kinase -> substrate	Robert H Newman (2013)
143	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
144	SP1_HUMAN	MAZ_HUMAN	TF -> target gene	TRANSFAC
145	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
146	M3K11_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
147	FOXO4_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
148	FOXO1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
149	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
150	SP1_HUMAN	SP3_HUMAN	TF -> target gene	TRANSFAC
151	PTN7_HUMAN	MK14_HUMAN	phosphatase -> substrate	KEGG
152	SP1_HUMAN	KC1A_HUMAN	TF -> target gene	TRANSFAC
153	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
154	MLTK_HUMAN	MP2K7_HUMAN	kinase -> substrate	KEGG
155	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
156	SP1_HUMAN	PHX2A_HUMAN	TF -> target gene	TRANSFAC
157	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
158	KPCD_HUMAN	NF2L2_HUMAN	kinase -> substrate	HPRD
159	STK16_HUMAN	IRF5_HUMAN	kinase -> substrate	Robert H Newman (2013)
160	KS6A5_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
161	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
162	EGFR_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
163	CHK1_HUMAN	P73_HUMAN	kinase -> substrate	RegPhos
164	GSK3B_HUMAN	CDX2_HUMAN	kinase -> substrate	RegPhos
165	PRGR_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
166	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
167	MP2K1_HUMAN	KS6A4_HUMAN	kinase -> substrate	RegPhos
168	PKN1_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
169	IKKA_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
170	STAT3_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
171	M3K5_HUMAN	MP2K6_HUMAN	kinase -> substrate	KEGG
172	SP1_HUMAN	HNF4A_HUMAN	TF -> target gene	TRANSFAC
173	EGFR_HUMAN	STA5B_HUMAN	kinase -> substrate	RegPhos
174	MK08_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
175	SRPK1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
176	KPCD_HUMAN	TWST1_HUMAN	kinase -> substrate	Robert H Newman (2013)
177	SP1_HUMAN	ATF2_HUMAN	TF -> target gene	TRANSFAC
178	RAGE_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
179	PTN1_HUMAN	STA5B_HUMAN	phosphatase -> substrate	HPRD
180	PTPRR_HUMAN	MK07_HUMAN	phosphatase -> substrate	HPRD
181	KS6A1_HUMAN	ESR2_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
182	PKN1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
183	LCK_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD; RegPhos
184	MP2K7_HUMAN	M3K7_HUMAN	kinase -> substrate	KEGG
185	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
186	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
187	CDK1_HUMAN	CUX1_HUMAN	kinase -> substrate	RegPhos
188	CDK2_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
189	CDK2_HUMAN	TFDP1_HUMAN	kinase -> substrate	RegPhos
190	CDK2_HUMAN	NFYA_HUMAN	kinase -> substrate	HPRD
191	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
192	TGFR2_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
193	CDK1_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
194	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
195	CDK1_HUMAN	HMGA2_HUMAN	kinase -> substrate	RegPhos
196	MK14_HUMAN	STAT4_HUMAN	kinase -> substrate	HPRD; NetPath
197	KC1A_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
198	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
199	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
200	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
201	PRDM1_HUMAN	PAX5_HUMAN	TF -> target gene	TRANSFAC
202	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
203	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
204	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
205	MP2K6_HUMAN	STAT4_HUMAN	kinase -> substrate	HPRD; RegPhos
206	MK07_HUMAN	MEF2D_HUMAN	kinase -> substrate	HPRD
207	M3K7_HUMAN	FUBP1_HUMAN	kinase -> substrate	Robert H Newman (2013)
208	CDK7_HUMAN	PO2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
209	M3K7_HUMAN	NLK_HUMAN	kinase -> substrate	KEGG
210	NLK_HUMAN	LEF1_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
211	BMR1B_HUMAN	OTU7B_HUMAN	kinase -> substrate	Robert H Newman (2013)
212	BMR1B_HUMAN	STABP_HUMAN	kinase -> substrate	RegPhos
213	BMR1B_HUMAN	MTA1_HUMAN	kinase -> substrate	Robert H Newman (2013)
214	BMR1B_HUMAN	ABI2_HUMAN	kinase -> substrate	Robert H Newman (2013)
215	BMR1B_HUMAN	MDFI_HUMAN	kinase -> substrate	Robert H Newman (2013)
216	BMR1B_HUMAN	FR1OP_HUMAN	kinase -> substrate	Robert H Newman (2013)
217	BMR1B_HUMAN	HCLS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
218	BMR1B_HUMAN	ENC2_HUMAN	kinase -> substrate	Robert H Newman (2013)
219	BMR1B_HUMAN	IF4A3_HUMAN	kinase -> substrate	Robert H Newman (2013)
220	BMR1B_HUMAN	NDF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
221	BMR1B_HUMAN	SMAD1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
222	BMR1B_HUMAN	CSRP3_HUMAN	kinase -> substrate	Robert H Newman (2013)
223	BMR1B_HUMAN	IFI27_HUMAN	kinase -> substrate	Robert H Newman (2013)
224	BMR1B_HUMAN	ASAP3_HUMAN	kinase -> substrate	Robert H Newman (2013)
225	BMR1B_HUMAN	DNJB2_HUMAN	kinase -> substrate	Robert H Newman (2013)
226	BMR1B_HUMAN	PHB2_HUMAN	kinase -> substrate	Robert H Newman (2013)
227	BMR1B_HUMAN	CRY1_HUMAN	kinase -> substrate	Robert H Newman (2013)
228	BMR1B_HUMAN	MLX_HUMAN	kinase -> substrate	Robert H Newman (2013)
229	BMR1B_HUMAN	KC1G2_HUMAN	kinase -> substrate	Robert H Newman (2013)
230	BMR1B_HUMAN	SRC8_HUMAN	kinase -> substrate	Robert H Newman (2013)

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network