Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MLX_HUMAN
Description:MLX, MAX dimerization protein [Source:HGNC Symbol;Acc:11645]
Location:chr17 q21.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T206LRKDVtALKIMPhosphoSitePlus
T102NSIGStSASSVPhosphoSitePlus
S74VEYAYsDNSLDPhosphoSitePlus
S105GSTSAsSVPNTPhosphoSitePlus
T110SSVPNtDDEDSPhosphoSitePlus
S106STSASsVPNTDPhosphoSitePlus
T87LFVEStRKGSVPhosphoSitePlus

Dephosphorylation site
MLX_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000246912S115fs*94COSMICOvarian Cancer21720365

Differential expressed protein
MLX_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MLX_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MK14_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
HIPK4_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
NEK9_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
MKNK1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
PRKY_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
DYRK3_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
M3K14_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
KPCI_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
SRPK1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
KSYK_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
CHK2_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
PDPK1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
CDK5_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
ST38L_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
DYRK4_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
CDK7_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
PLK1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
CSK21_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
BUB1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
STYK1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
BMR1B_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
CDKL5_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANMLX_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
MLX_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008134transcription factor bindingIPImolecular_function
GO:0006112energy reserve metabolic processTASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0006355regulation of transcription, DNA-dependentNASbiological_process
GO:0005634nucleusIEAcellular_component
GO:0031325positive regulation of cellular metabolic processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0006913nucleocytoplasmic transportIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0046982protein heterodimerization activityIPImolecular_function
GO:0003700sequence-specific DNA binding transcription factorNASmolecular_function
GO:0042803protein homodimerization activityIPImolecular_function
GO:0046983protein dimerization activityIEAmolecular_function
GO:0003677DNA bindingIDAmolecular_function