Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CSRP3_HUMAN
Description:cysteine and glycine-rich protein 3 (cardiac LIM protein) [Source:HGNC Symbol;Acc:2472]
Location:chr11 p15.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T16GACEKtVYHAELIMPhosphoSitePlus
Y73PKGIGyGQGAGPhosphoSitePlus
S95LQFQQsPKPARPhosphoSitePlus
Y18CEKTVyHAEEILIMPhosphoSitePlus
Y167KDGELyCKVCYLIM; Zn_ribbon_2PhosphoSitePlus
Y57HESEIyCKVCYLIMPhosphoSitePlus
Y172YCKVCyAKNFGLIM; Zn_ribbon_2PhosphoSitePlus
S54VAAHEsEIYCKLIMPhosphoSitePlus

Dephosphorylation site
CSRP3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000265968A43TCOSMICHead and Neck Cancer21798893

Differential expressed protein
CSRP3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CSRP3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NEK4_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
CDK4_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
RAF1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
BUB1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
MK14_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
FAK1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
TGFR2_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
KCC4_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
CDK5_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
FYN_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
KCC2A_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
MAPK3_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
GSK3B_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
CDK6_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
KKCC1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
FGFR1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
FRK_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
MOS_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
MAPK5_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
KPCD_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
SNRK_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
ITK_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
KS6A2_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
BMR1A_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
NTKL_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
CSK21_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
CLK1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
STYK1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
CDK7_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
VRK1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
UHMK1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
BMR1B_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
DYRK3_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
HIPK4_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
KS6A5_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
MK01_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
PXK_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
AKT1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
BMPR2_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
NLK_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
NEK6_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
CDK9_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
FGFR4_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
PKN1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
PIM1_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
LYN_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANCSRP3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CSRP3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008307structural constituent of muscleIMPmolecular_function
GO:0055003cardiac myofibril assemblyISSbiological_process
GO:0005856cytoskeletonIEAcellular_component
GO:0033365protein localization to organelleIEAbiological_process
GO:0002026regulation of the force of heart contractionIEAbiological_process
GO:0030018Z discIEAcellular_component
GO:0035995detection of muscle stretchIEAbiological_process
GO:0035995detection of muscle stretchIMPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0060048cardiac muscle contractionIEAbiological_process
GO:0060048cardiac muscle contractionIMPbiological_process
GO:0042805actinin bindingIEAmolecular_function
GO:0008307structural constituent of muscleIEAmolecular_function
GO:0030018Z discIDAcellular_component
GO:0055003cardiac myofibril assemblyIEAbiological_process
GO:0042805actinin bindingISSmolecular_function
GO:0007519skeletal muscle tissue developmentTASbiological_process
GO:0031433telethonin bindingIEAmolecular_function
GO:0048738cardiac muscle tissue developmentISSbiological_process
GO:0003300cardiac muscle hypertrophyIMPbiological_process
GO:0005634nucleusIEAcellular_component
GO:0006874cellular calcium ion homeostasisIEAbiological_process
GO:0002026regulation of the force of heart contractionISSbiological_process
GO:0033365protein localization to organelleIMPbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0006874cellular calcium ion homeostasisISSbiological_process
GO:0031433telethonin bindingIDAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0048738cardiac muscle tissue developmentIEAbiological_process