Human Phosphorylation Mediated
                                 Signaling Transduction Network

You are querying signaling transduction network mediated by BMR1A_HUMAN in Hepatocellular Carcinoma.

Signaling Transduction Network:

NO.	Source	Protein Attribute+	Target	Protein Attribute+	Relation Attribute	Resource
1	BMP4_HUMAN		BMR1A_HUMAN		ligand -> receptor	HPMR
2	BMP2_HUMAN		BMR1A_HUMAN		ligand -> receptor	HPMR
3	BMP6_HUMAN		BMR1A_HUMAN		ligand -> receptor	HPMR
4	BMP7_HUMAN		BMR1A_HUMAN		ligand -> receptor	HPMR
5	BMR1A_HUMAN		ZAP70_HUMAN		kinase -> substrate	Robert H Newman (2013)
6	BMR1A_HUMAN		KPCD_HUMAN		kinase -> substrate	Robert H Newman (2013)
7	BMR1A_HUMAN		BMX_HUMAN		kinase -> substrate	Robert H Newman (2013)
8	ZAP70_HUMAN		MK14_HUMAN		kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
9	KPCD_HUMAN		CDK9_HUMAN		kinase -> substrate	Robert H Newman (2013)
10	KPCD_HUMAN		HNRPK_HUMAN		kinase -> substrate	HPRD; Robert H Newman (2013)
11	KPCD_HUMAN		KKCC1_HUMAN		kinase -> substrate	Robert H Newman (2013)
12	ZAP70_HUMAN		KPCA_HUMAN		kinase -> substrate	Robert H Newman (2013)
13	BMX_HUMAN		KPCB_HUMAN		kinase -> substrate	Robert H Newman (2013)
14	KPCD_HUMAN		TWST1_HUMAN		kinase -> substrate	Robert H Newman (2013)
15	KPCD_HUMAN		STAT3_HUMAN		kinase -> substrate	HPRD; NetPath
16	KPCD_HUMAN		KS6B2_HUMAN		kinase -> substrate	Robert H Newman (2013)
17	ZAP70_HUMAN		FGR_HUMAN		kinase -> substrate	Robert H Newman (2013)
18	KPCD_HUMAN		GSK3A_HUMAN		kinase -> substrate	HPRD
19	KPCD_HUMAN		EP300_HUMAN		kinase -> substrate	HPRD; Robert H Newman (2013)
20	BMX_HUMAN		HNRPK_HUMAN		kinase -> substrate	Robert H Newman (2013)
21	KPCD_HUMAN		STAT1_HUMAN		kinase -> substrate	HPRD
22	KPCD_HUMAN		ARBK1_HUMAN		kinase -> substrate	HPRD
23	KPCD_HUMAN		NF2L2_HUMAN		kinase -> substrate	HPRD
24	ZAP70_HUMAN		DUS3_HUMAN		kinase -> substrate	HPRD; RegPhos; NetPath; Robert H Newman (2013)
25	KPCD_HUMAN		AKT3_HUMAN		kinase -> substrate	HPRD
26	KPCD_HUMAN		PTN22_HUMAN		kinase -> substrate	HPRD
27	KPCD_HUMAN		EGFR_HUMAN		kinase -> substrate	HPRD
28	KPCD_HUMAN		PTPRA_HUMAN		kinase -> substrate	HPRD; Robert H Newman (2013)
29	KPCD_HUMAN		KPCD1_HUMAN		kinase -> substrate	Robert H Newman (2013)
30	MK14_HUMAN		KS6A4_HUMAN		kinase -> substrate	KEGG; HPRD; Robert H Newman (2013)
31	CDK9_HUMAN		ETS1_HUMAN		kinase -> substrate	Robert H Newman (2013)
32	MK14_HUMAN		ELK3_HUMAN		kinase -> substrate	HPRD
33	HNRPK_HUMAN		MYC_HUMAN		TF -> target gene	TRANSFAC
34	KKCC1_HUMAN		AKT1_HUMAN		kinase -> substrate	HPRD
35	KPCA_HUMAN		SRF_HUMAN		kinase -> substrate	Robert H Newman (2013)
36	MK14_HUMAN		P53_HUMAN		kinase -> substrate	KEGG; HPRD
37	KPCB_HUMAN		BTK_HUMAN		kinase -> substrate	HPRD; NetPath
38	MK14_HUMAN		STAT4_HUMAN		kinase -> substrate	HPRD; NetPath
39	STAT3_HUMAN		MYC_HUMAN		TF -> target gene	TRANSFAC
40	KS6B2_HUMAN		ETS1_HUMAN		kinase -> substrate	Robert H Newman (2013)
41	KPCA_HUMAN		NFKB1_HUMAN		kinase -> substrate	HPRD
42	MK14_HUMAN		SIK1_HUMAN		kinase -> substrate	Robert H Newman (2013)
43	MK14_HUMAN		MEF2A_HUMAN		kinase -> substrate	HPRD; Robert H Newman (2013)
44	FGR_HUMAN		SRF_HUMAN		kinase -> substrate	Robert H Newman (2013)
45	KPCA_HUMAN		ATF1_HUMAN		kinase -> substrate	HPRD
46	MK14_HUMAN		CREB1_HUMAN		kinase -> substrate	Robert H Newman (2013)
47	KPCA_HUMAN		CTNB1_HUMAN		kinase -> substrate	KEGG
48	GSK3A_HUMAN		MYC_HUMAN		kinase -> substrate	RegPhos; Robert H Newman (2013)
49	FGR_HUMAN		CSK21_HUMAN		kinase -> substrate	Robert H Newman (2013)
50	KPCA_HUMAN		CREM_HUMAN		kinase -> substrate	HPRD
51	KPCA_HUMAN		GLI1_HUMAN		kinase -> substrate	KEGG
52	KPCA_HUMAN		AHR_HUMAN		kinase -> substrate	Robert H Newman (2013)
53	STAT1_HUMAN		IRF1_HUMAN		TF -> target gene	TRANSFAC
54	STAT1_HUMAN		MYC_HUMAN		TF -> target gene	KEGG
55	ARBK1_HUMAN		P53_HUMAN		kinase -> substrate	Robert H Newman (2013)
56	KPCA_HUMAN		ATF4_HUMAN		kinase -> substrate	KEGG
57	KPCB_HUMAN		IKKA_HUMAN		kinase -> substrate	NetPath
58	DUS3_HUMAN		MP2K2_HUMAN		phosphatase -> substrate	HPRD
59	KPCA_HUMAN		P53_HUMAN		kinase -> substrate	HPRD
60	FGR_HUMAN		RXRG_HUMAN		kinase -> substrate	Robert H Newman (2013)
61	GSK3A_HUMAN		RXRA_HUMAN		kinase -> substrate	Robert H Newman (2013)
62	KPCA_HUMAN		PTN7_HUMAN		kinase -> substrate	HPRD
63	FGR_HUMAN		RXRA_HUMAN		kinase -> substrate	Robert H Newman (2013)
64	FGR_HUMAN		ETS1_HUMAN		kinase -> substrate	Robert H Newman (2013)
65	CDK9_HUMAN		P53_HUMAN		kinase -> substrate	RegPhos
66	MK14_HUMAN		TF65_HUMAN		kinase -> substrate	Robert H Newman (2013)
67	KPCA_HUMAN		KLF1_HUMAN		kinase -> substrate	HPRD
68	AKT3_HUMAN		FOXO1_HUMAN		kinase -> substrate	KEGG
69	MK14_HUMAN		ELK1_HUMAN		kinase -> substrate	KEGG; HPRD; NetPath; Robert H Newman (2013)
70	PTN22_HUMAN		LCK_HUMAN		phosphatase -> substrate	HPRD
71	TWST1_HUMAN		GLI1_HUMAN		TF -> target gene	TRANSFAC
72	MK14_HUMAN		MAPK5_HUMAN		kinase -> substrate	KEGG; HPRD; Robert H Newman (2013)
73	MK14_HUMAN		MPIP3_HUMAN		kinase -> substrate	HPRD
74	AKT3_HUMAN		MP2K4_HUMAN		kinase -> substrate	KEGG
75	EGFR_HUMAN		STA5A_HUMAN		kinase -> substrate	KEGG
76	MK14_HUMAN		HNF4A_HUMAN		kinase -> substrate	HPRD
77	KPCA_HUMAN		KGP1_HUMAN		kinase -> substrate	HPRD; Robert H Newman (2013)
78	STAT3_HUMAN		FOS_HUMAN		TF -> target gene	TRANSFAC
79	KPCA_HUMAN		SRC_HUMAN		kinase -> substrate; other	HPRD; KEGG
80	MK14_HUMAN		ATF2_HUMAN		kinase -> substrate	NetPath; Robert H Newman (2013)
81	PTPRA_HUMAN		SRC_HUMAN		phosphatase -> substrate	HPRD
82	KPCA_HUMAN		MYOD1_HUMAN		kinase -> substrate	HPRD
83	MK14_HUMAN		PTN7_HUMAN		kinase -> substrate	HPRD
84	FGR_HUMAN		SRC_HUMAN		kinase -> substrate	HPRD; RegPhos
85	KPCA_HUMAN		RXRA_HUMAN		kinase -> substrate	Robert H Newman (2013)
86	GSK3A_HUMAN		CREM_HUMAN		kinase -> substrate	HPRD; RegPhos
87	KPCA_HUMAN		FYN_HUMAN		kinase -> substrate	Robert H Newman (2013)
88	KPCA_HUMAN		STK11_HUMAN		kinase -> substrate	HPRD
89	CDK9_HUMAN		ANDR_HUMAN		kinase -> substrate	NetPath
90	PTPRA_HUMAN		FYN_HUMAN		phosphatase -> substrate	HPRD
91	MK14_HUMAN		CDX2_HUMAN		kinase -> substrate	HPRD
92	GSK3A_HUMAN		HSF1_HUMAN		kinase -> substrate	HPRD; RegPhos
93	KPCA_HUMAN		LCK_HUMAN		kinase -> substrate	HPRD
94	MK14_HUMAN		ELK4_HUMAN		kinase -> substrate	KEGG
95	STAT3_HUMAN		IRF1_HUMAN		TF -> target gene	TRANSFAC
96	CDK9_HUMAN		CHK2_HUMAN		kinase -> substrate	Robert H Newman (2013)
97	AKT3_HUMAN		MTOR_HUMAN		kinase -> substrate	KEGG
98	KPCA_HUMAN		RXRG_HUMAN		kinase -> substrate	Robert H Newman (2013)
99	KPCD1_HUMAN		KSYK_HUMAN		kinase -> substrate	NetPath
100	KPCA_HUMAN		PTPRR_HUMAN		kinase -> substrate	HPRD
101	MK14_HUMAN		ESR1_HUMAN		kinase -> substrate	HPRD; Robert H Newman (2013)
102	MK14_HUMAN		KSYK_HUMAN		kinase -> substrate	Robert H Newman (2013)
103	MK14_HUMAN		MAPK3_HUMAN		kinase -> substrate	KEGG
104	GSK3A_HUMAN		TF7L2_HUMAN		kinase -> substrate	Robert H Newman (2013)
105	KKCC1_HUMAN		IRF3_HUMAN		kinase -> substrate	Robert H Newman (2013)
106	EGFR_HUMAN		STA5B_HUMAN		kinase -> substrate	RegPhos
107	KPCA_HUMAN		TF65_HUMAN		kinase -> substrate	HPRD
108	KPCA_HUMAN		FOS_HUMAN		kinase -> substrate	HPRD
109	KPCA_HUMAN		IRF3_HUMAN		kinase -> substrate	Robert H Newman (2013)
110	KS6A4_HUMAN		KS6A2_HUMAN		kinase -> substrate	Robert H Newman (2013)
111	ETS1_HUMAN		AP2A_HUMAN		TF -> target gene	TRANSFAC
112	MYC_HUMAN		CDK4_HUMAN		TF -> target gene	TRANSFAC
113	AKT1_HUMAN		MK08_HUMAN		kinase -> substrate	Robert H Newman (2013)
114	SRF_HUMAN		EGR2_HUMAN		TF -> target gene	TRANSFAC
115	SRF_HUMAN		EGR1_HUMAN		TF -> target gene	TRANSFAC
116	P53_HUMAN		P63_HUMAN		TF -> target gene	TRANSFAC
117	BTK_HUMAN		KS6A2_HUMAN		kinase -> substrate	Robert H Newman (2013)
118	SIK1_HUMAN		CRTC2_HUMAN		kinase -> substrate	HPRD
119	CREB1_HUMAN		IBP1_HUMAN		TF -> target gene	TRANSFAC
120	CSK21_HUMAN		APEX1_HUMAN		kinase -> substrate	HPRD
121	P53_HUMAN		BBC3_HUMAN		TF -> target gene	TRANSFAC
122	IKKA_HUMAN		IRF7_HUMAN		kinase -> substrate	KEGG
123	MP2K2_HUMAN		KS6A2_HUMAN		kinase -> substrate	Robert H Newman (2013)
124	RXRA_HUMAN		RARB_HUMAN		TF -> target gene	TRANSFAC
125	BTK_HUMAN		GTF2I_HUMAN		kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
126	PTN7_HUMAN		MK08_HUMAN		phosphatase -> substrate	KEGG
127	BTK_HUMAN		MK08_HUMAN		kinase -> substrate	Robert H Newman (2013)
128	CSK21_HUMAN		VDR_HUMAN		kinase -> substrate	HPRD; Robert H Newman (2013)
129	KS6A4_HUMAN		PO6F1_HUMAN		kinase -> substrate	Robert H Newman (2013)
130	LCK_HUMAN		VDR_HUMAN		kinase -> substrate	Robert H Newman (2013)
131	MAPK5_HUMAN		MK08_HUMAN		kinase -> substrate	Robert H Newman (2013)
132	MPIP3_HUMAN		CDK1_HUMAN		phosphatase -> substrate	HPRD
133	P53_HUMAN		P73_HUMAN		TF -> target gene	KEGG; TRANSFAC
134	CSK21_HUMAN		CDK1_HUMAN		kinase -> substrate	HPRD; Robert H Newman (2013)
135	CSK21_HUMAN		HIF1A_HUMAN		kinase -> substrate	HPRD
136	MP2K4_HUMAN		MK08_HUMAN		kinase -> substrate	KEGG; HPRD; RegPhos; NetPath; Robert H Newman (201
137	KGP1_HUMAN		KS6A2_HUMAN		kinase -> substrate	Robert H Newman (2013)
138	SRC_HUMAN		RHG35_HUMAN		kinase -> substrate	KEGG; HPRD; RegPhos
139	MEF2A_HUMAN		MYOG_HUMAN		TF -> target gene	TRANSFAC
140	SRC_HUMAN		GTF2I_HUMAN		kinase -> substrate	RegPhos
141	CSK21_HUMAN		MAZ_HUMAN		kinase -> substrate	HPRD
142	FYN_HUMAN		CDK5_HUMAN		kinase -> substrate	HPRD; RegPhos
143	CSK21_HUMAN		NKX25_HUMAN		kinase -> substrate	HPRD
144	STK11_HUMAN		TFE3_HUMAN		kinase -> substrate	Robert H Newman (2013)
145	AKT1_HUMAN		FOXO4_HUMAN		kinase -> substrate	RegPhos
146	ATF1_HUMAN		EGR1_HUMAN		TF -> target gene	TRANSFAC
147	AKT1_HUMAN		TEAD1_HUMAN		kinase -> substrate	Robert H Newman (2013)
148	AKT1_HUMAN		GATA1_HUMAN		kinase -> substrate	HPRD; RegPhos
149	KGP1_HUMAN		GTF2I_HUMAN		kinase -> substrate	HPRD
150	CHK2_HUMAN		E2F1_HUMAN		kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
151	MTOR_HUMAN		HIF1A_HUMAN		kinase -> substrate	KEGG
152	AKT1_HUMAN		STAT6_HUMAN		kinase -> substrate	Robert H Newman (2013)
153	KSYK_HUMAN		KS6A2_HUMAN		kinase -> substrate	Robert H Newman (2013)
154	KGP1_HUMAN		MK07_HUMAN		kinase -> substrate	Robert H Newman (2013)
155	PTPRR_HUMAN		MK07_HUMAN		phosphatase -> substrate	HPRD
156	CREB1_HUMAN		EGR1_HUMAN		TF -> target gene	TRANSFAC
157	MAPK3_HUMAN		MYF6_HUMAN		kinase -> substrate	Robert H Newman (2013)
158	FYN_HUMAN		MK07_HUMAN		kinase -> substrate	Robert H Newman (2013)
159	AKT1_HUMAN		GATA2_HUMAN		kinase -> substrate	HPRD
160	CSK21_HUMAN		MYF6_HUMAN		kinase -> substrate	Robert H Newman (2013)
161	ELK1_HUMAN		EGR2_HUMAN		TF -> target gene	TRANSFAC
162	AKT1_HUMAN		THA_HUMAN		kinase -> substrate	Robert H Newman (2013)
163	CSK21_HUMAN		EGR1_HUMAN		kinase -> substrate	HPRD
164	FOXO1_HUMAN		IBP1_HUMAN		TF -> target gene	TRANSFAC
165	AKT1_HUMAN		SOX9_HUMAN		kinase -> substrate	Robert H Newman (2013)
166	KS6A2_HUMAN		CSEN_HUMAN		kinase -> substrate	Robert H Newman (2013)
167	CDK4_HUMAN		FOXN2_HUMAN		kinase -> substrate	Robert H Newman (2013)
168	MK08_HUMAN		NFAC2_HUMAN		kinase -> substrate	KEGG
169	KS6A2_HUMAN		GABPA_HUMAN		kinase -> substrate	Robert H Newman (2013)
170	MK08_HUMAN		PAX2_HUMAN		kinase -> substrate	NetPath
171	CDK4_HUMAN		PKNX1_HUMAN		kinase -> substrate	Robert H Newman (2013)
172	MK08_HUMAN		DYR1B_HUMAN		kinase -> substrate	Robert H Newman (2013)
173	MK08_HUMAN		JUND_HUMAN		kinase -> substrate	KEGG
174	CDK1_HUMAN		CUX1_HUMAN		kinase -> substrate	RegPhos
175	CDK1_HUMAN		CDK7_HUMAN		kinase -> substrate	RegPhos
176	CDK5_HUMAN		MEF2D_HUMAN		kinase -> substrate	RegPhos
177	MK07_HUMAN		MEF2D_HUMAN		kinase -> substrate	HPRD
178	CDK1_HUMAN		HMGA2_HUMAN		kinase -> substrate	RegPhos
179	NFAC2_HUMAN		EGR3_HUMAN		TF -> target gene	TRANSFAC
180	DYR1B_HUMAN		HNF1A_HUMAN		kinase -> substrate	RegPhos; Robert H Newman (2013)
181	CDK7_HUMAN		PO2F1_HUMAN		kinase -> substrate	RegPhos; Robert H Newman (2013)
182	BMR1A_HUMAN		SYSC_HUMAN		kinase -> substrate	Robert H Newman (2013)
183	BMR1A_HUMAN		SMAD1_HUMAN		kinase -> substrate	KEGG
184	BMR1A_HUMAN		AIRE_HUMAN		kinase -> substrate	Robert H Newman (2013)
185	BMR1A_HUMAN		RUVB1_HUMAN		kinase -> substrate	Robert H Newman (2013)
186	BMR1A_HUMAN		SRXN1_HUMAN		kinase -> substrate	Robert H Newman (2013)
187	BMR1A_HUMAN		HCLS1_HUMAN		kinase -> substrate	Robert H Newman (2013)
188	BMR1A_HUMAN		BPL1_HUMAN		kinase -> substrate	Robert H Newman (2013)
189	BMR1A_HUMAN		CSRP3_HUMAN		kinase -> substrate	Robert H Newman (2013)
190	BMR1A_HUMAN		IF2A_HUMAN		kinase -> substrate	Robert H Newman (2013)
191	BMR1A_HUMAN		KAPCB_HUMAN		kinase -> substrate	Robert H Newman (2013)
192	BMR1A_HUMAN		NDF1_HUMAN		kinase -> substrate	Robert H Newman (2013)
193	BMR1A_HUMAN		ASAP3_HUMAN		kinase -> substrate	Robert H Newman (2013)

+Protein attribute: protein with cancer-related variations (CanProVar) up expressed protein; down expressed protein(dbDEPC) protein with hyperphosphorylation site (PhosphoSitePlus)

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