Phosphorylation

You are querying signaling transduction network mediated by BMR1A_HUMAN in Hepatocellular Carcinoma.

Signaling Transduction Network:

NO.	Source	Target	Relation Attribute	Resource
1	BMP4_HUMAN	BMR1A_HUMAN	ligand -> receptor	HPMR
2	BMP2_HUMAN	BMR1A_HUMAN	ligand -> receptor	HPMR
3	BMP6_HUMAN	BMR1A_HUMAN	ligand -> receptor	HPMR
4	BMP7_HUMAN	BMR1A_HUMAN	ligand -> receptor	HPMR
5	BMR1A_HUMAN	ZAP70_HUMAN	kinase -> substrate	Robert H Newman (2013)
6	BMR1A_HUMAN	KPCD_HUMAN	kinase -> substrate	Robert H Newman (2013)
7	BMR1A_HUMAN	BMX_HUMAN	kinase -> substrate	Robert H Newman (2013)
8	ZAP70_HUMAN	MK14_HUMAN	kinase -> substrate	KEGG; RegPhos; Robert H Newman (2013)
9	KPCD_HUMAN	CDK9_HUMAN	kinase -> substrate	Robert H Newman (2013)
10	KPCD_HUMAN	HNRPK_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
11	KPCD_HUMAN	KKCC1_HUMAN	kinase -> substrate	Robert H Newman (2013)
12	ZAP70_HUMAN	KPCA_HUMAN	kinase -> substrate	Robert H Newman (2013)
13	BMX_HUMAN	KPCB_HUMAN	kinase -> substrate	Robert H Newman (2013)
14	KPCD_HUMAN	TWST1_HUMAN	kinase -> substrate	Robert H Newman (2013)
15	KPCD_HUMAN	STAT3_HUMAN	kinase -> substrate	HPRD; NetPath
16	KPCD_HUMAN	KS6B2_HUMAN	kinase -> substrate	Robert H Newman (2013)
17	ZAP70_HUMAN	FGR_HUMAN	kinase -> substrate	Robert H Newman (2013)
18	KPCD_HUMAN	GSK3A_HUMAN	kinase -> substrate	HPRD
19	KPCD_HUMAN	EP300_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
20	BMX_HUMAN	HNRPK_HUMAN	kinase -> substrate	Robert H Newman (2013)
21	KPCD_HUMAN	STAT1_HUMAN	kinase -> substrate	HPRD
22	KPCD_HUMAN	ARBK1_HUMAN	kinase -> substrate	HPRD
23	KPCD_HUMAN	NF2L2_HUMAN	kinase -> substrate	HPRD
24	ZAP70_HUMAN	DUS3_HUMAN	kinase -> substrate	HPRD; RegPhos; NetPath; Robert H Newman (2013)
25	KPCD_HUMAN	AKT3_HUMAN	kinase -> substrate	HPRD
26	KPCD_HUMAN	PTN22_HUMAN	kinase -> substrate	HPRD
27	KPCD_HUMAN	EGFR_HUMAN	kinase -> substrate	HPRD
28	KPCD_HUMAN	PTPRA_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
29	KPCD_HUMAN	KPCD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
30	MK14_HUMAN	KS6A4_HUMAN	kinase -> substrate	KEGG; HPRD; Robert H Newman (2013)
31	CDK9_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
32	MK14_HUMAN	ELK3_HUMAN	kinase -> substrate	HPRD
33	HNRPK_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
34	KKCC1_HUMAN	AKT1_HUMAN	kinase -> substrate	HPRD
35	KPCA_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
36	MK14_HUMAN	P53_HUMAN	kinase -> substrate	KEGG; HPRD
37	KPCB_HUMAN	BTK_HUMAN	kinase -> substrate	HPRD; NetPath
38	MK14_HUMAN	STAT4_HUMAN	kinase -> substrate	HPRD; NetPath
39	STAT3_HUMAN	MYC_HUMAN	TF -> target gene	TRANSFAC
40	KS6B2_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
41	KPCA_HUMAN	NFKB1_HUMAN	kinase -> substrate	HPRD
42	MK14_HUMAN	SIK1_HUMAN	kinase -> substrate	Robert H Newman (2013)
43	MK14_HUMAN	MEF2A_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
44	FGR_HUMAN	SRF_HUMAN	kinase -> substrate	Robert H Newman (2013)
45	KPCA_HUMAN	ATF1_HUMAN	kinase -> substrate	HPRD
46	MK14_HUMAN	CREB1_HUMAN	kinase -> substrate	Robert H Newman (2013)
47	KPCA_HUMAN	CTNB1_HUMAN	kinase -> substrate	KEGG
48	GSK3A_HUMAN	MYC_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
49	FGR_HUMAN	CSK21_HUMAN	kinase -> substrate	Robert H Newman (2013)
50	KPCA_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD
51	KPCA_HUMAN	GLI1_HUMAN	kinase -> substrate	KEGG
52	KPCA_HUMAN	AHR_HUMAN	kinase -> substrate	Robert H Newman (2013)
53	STAT1_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
54	STAT1_HUMAN	MYC_HUMAN	TF -> target gene	KEGG
55	ARBK1_HUMAN	P53_HUMAN	kinase -> substrate	Robert H Newman (2013)
56	KPCA_HUMAN	ATF4_HUMAN	kinase -> substrate	KEGG
57	KPCB_HUMAN	IKKA_HUMAN	kinase -> substrate	NetPath
58	DUS3_HUMAN	MP2K2_HUMAN	phosphatase -> substrate	HPRD
59	KPCA_HUMAN	P53_HUMAN	kinase -> substrate	HPRD
60	FGR_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
61	GSK3A_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
62	KPCA_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
63	FGR_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
64	FGR_HUMAN	ETS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
65	CDK9_HUMAN	P53_HUMAN	kinase -> substrate	RegPhos
66	MK14_HUMAN	TF65_HUMAN	kinase -> substrate	Robert H Newman (2013)
67	KPCA_HUMAN	KLF1_HUMAN	kinase -> substrate	HPRD
68	AKT3_HUMAN	FOXO1_HUMAN	kinase -> substrate	KEGG
69	MK14_HUMAN	ELK1_HUMAN	kinase -> substrate	KEGG; HPRD; NetPath; Robert H Newman (2013)
70	PTN22_HUMAN	LCK_HUMAN	phosphatase -> substrate	HPRD
71	TWST1_HUMAN	GLI1_HUMAN	TF -> target gene	TRANSFAC
72	MK14_HUMAN	MAPK5_HUMAN	kinase -> substrate	KEGG; HPRD; Robert H Newman (2013)
73	MK14_HUMAN	MPIP3_HUMAN	kinase -> substrate	HPRD
74	AKT3_HUMAN	MP2K4_HUMAN	kinase -> substrate	KEGG
75	EGFR_HUMAN	STA5A_HUMAN	kinase -> substrate	KEGG
76	MK14_HUMAN	HNF4A_HUMAN	kinase -> substrate	HPRD
77	KPCA_HUMAN	KGP1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
78	STAT3_HUMAN	FOS_HUMAN	TF -> target gene	TRANSFAC
79	KPCA_HUMAN	SRC_HUMAN	kinase -> substrate; other	HPRD; KEGG
80	MK14_HUMAN	ATF2_HUMAN	kinase -> substrate	NetPath; Robert H Newman (2013)
81	PTPRA_HUMAN	SRC_HUMAN	phosphatase -> substrate	HPRD
82	KPCA_HUMAN	MYOD1_HUMAN	kinase -> substrate	HPRD
83	MK14_HUMAN	PTN7_HUMAN	kinase -> substrate	HPRD
84	FGR_HUMAN	SRC_HUMAN	kinase -> substrate	HPRD; RegPhos
85	KPCA_HUMAN	RXRA_HUMAN	kinase -> substrate	Robert H Newman (2013)
86	GSK3A_HUMAN	CREM_HUMAN	kinase -> substrate	HPRD; RegPhos
87	KPCA_HUMAN	FYN_HUMAN	kinase -> substrate	Robert H Newman (2013)
88	KPCA_HUMAN	STK11_HUMAN	kinase -> substrate	HPRD
89	CDK9_HUMAN	ANDR_HUMAN	kinase -> substrate	NetPath
90	PTPRA_HUMAN	FYN_HUMAN	phosphatase -> substrate	HPRD
91	MK14_HUMAN	CDX2_HUMAN	kinase -> substrate	HPRD
92	GSK3A_HUMAN	HSF1_HUMAN	kinase -> substrate	HPRD; RegPhos
93	KPCA_HUMAN	LCK_HUMAN	kinase -> substrate	HPRD
94	MK14_HUMAN	ELK4_HUMAN	kinase -> substrate	KEGG
95	STAT3_HUMAN	IRF1_HUMAN	TF -> target gene	TRANSFAC
96	CDK9_HUMAN	CHK2_HUMAN	kinase -> substrate	Robert H Newman (2013)
97	AKT3_HUMAN	MTOR_HUMAN	kinase -> substrate	KEGG
98	KPCA_HUMAN	RXRG_HUMAN	kinase -> substrate	Robert H Newman (2013)
99	KPCD1_HUMAN	KSYK_HUMAN	kinase -> substrate	NetPath
100	KPCA_HUMAN	PTPRR_HUMAN	kinase -> substrate	HPRD
101	MK14_HUMAN	ESR1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
102	MK14_HUMAN	KSYK_HUMAN	kinase -> substrate	Robert H Newman (2013)
103	MK14_HUMAN	MAPK3_HUMAN	kinase -> substrate	KEGG
104	GSK3A_HUMAN	TF7L2_HUMAN	kinase -> substrate	Robert H Newman (2013)
105	KKCC1_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
106	EGFR_HUMAN	STA5B_HUMAN	kinase -> substrate	RegPhos
107	KPCA_HUMAN	TF65_HUMAN	kinase -> substrate	HPRD
108	KPCA_HUMAN	FOS_HUMAN	kinase -> substrate	HPRD
109	KPCA_HUMAN	IRF3_HUMAN	kinase -> substrate	Robert H Newman (2013)
110	KS6A4_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
111	ETS1_HUMAN	AP2A_HUMAN	TF -> target gene	TRANSFAC
112	MYC_HUMAN	CDK4_HUMAN	TF -> target gene	TRANSFAC
113	AKT1_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
114	SRF_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
115	SRF_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
116	P53_HUMAN	P63_HUMAN	TF -> target gene	TRANSFAC
117	BTK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
118	SIK1_HUMAN	CRTC2_HUMAN	kinase -> substrate	HPRD
119	CREB1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
120	CSK21_HUMAN	APEX1_HUMAN	kinase -> substrate	HPRD
121	P53_HUMAN	BBC3_HUMAN	TF -> target gene	TRANSFAC
122	IKKA_HUMAN	IRF7_HUMAN	kinase -> substrate	KEGG
123	MP2K2_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
124	RXRA_HUMAN	RARB_HUMAN	TF -> target gene	TRANSFAC
125	BTK_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos; NetPath; Robert H Newman (2013)
126	PTN7_HUMAN	MK08_HUMAN	phosphatase -> substrate	KEGG
127	BTK_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
128	CSK21_HUMAN	VDR_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
129	KS6A4_HUMAN	PO6F1_HUMAN	kinase -> substrate	Robert H Newman (2013)
130	LCK_HUMAN	VDR_HUMAN	kinase -> substrate	Robert H Newman (2013)
131	MAPK5_HUMAN	MK08_HUMAN	kinase -> substrate	Robert H Newman (2013)
132	MPIP3_HUMAN	CDK1_HUMAN	phosphatase -> substrate	HPRD
133	P53_HUMAN	P73_HUMAN	TF -> target gene	KEGG; TRANSFAC
134	CSK21_HUMAN	CDK1_HUMAN	kinase -> substrate	HPRD; Robert H Newman (2013)
135	CSK21_HUMAN	HIF1A_HUMAN	kinase -> substrate	HPRD
136	MP2K4_HUMAN	MK08_HUMAN	kinase -> substrate	KEGG; HPRD; RegPhos; NetPath; Robert H Newman (201
137	KGP1_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
138	SRC_HUMAN	RHG35_HUMAN	kinase -> substrate	KEGG; HPRD; RegPhos
139	MEF2A_HUMAN	MYOG_HUMAN	TF -> target gene	TRANSFAC
140	SRC_HUMAN	GTF2I_HUMAN	kinase -> substrate	RegPhos
141	CSK21_HUMAN	MAZ_HUMAN	kinase -> substrate	HPRD
142	FYN_HUMAN	CDK5_HUMAN	kinase -> substrate	HPRD; RegPhos
143	CSK21_HUMAN	NKX25_HUMAN	kinase -> substrate	HPRD
144	STK11_HUMAN	TFE3_HUMAN	kinase -> substrate	Robert H Newman (2013)
145	AKT1_HUMAN	FOXO4_HUMAN	kinase -> substrate	RegPhos
146	ATF1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
147	AKT1_HUMAN	TEAD1_HUMAN	kinase -> substrate	Robert H Newman (2013)
148	AKT1_HUMAN	GATA1_HUMAN	kinase -> substrate	HPRD; RegPhos
149	KGP1_HUMAN	GTF2I_HUMAN	kinase -> substrate	HPRD
150	CHK2_HUMAN	E2F1_HUMAN	kinase -> substrate	HPRD; RegPhos; Robert H Newman (2013)
151	MTOR_HUMAN	HIF1A_HUMAN	kinase -> substrate	KEGG
152	AKT1_HUMAN	STAT6_HUMAN	kinase -> substrate	Robert H Newman (2013)
153	KSYK_HUMAN	KS6A2_HUMAN	kinase -> substrate	Robert H Newman (2013)
154	KGP1_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
155	PTPRR_HUMAN	MK07_HUMAN	phosphatase -> substrate	HPRD
156	CREB1_HUMAN	EGR1_HUMAN	TF -> target gene	TRANSFAC
157	MAPK3_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
158	FYN_HUMAN	MK07_HUMAN	kinase -> substrate	Robert H Newman (2013)
159	AKT1_HUMAN	GATA2_HUMAN	kinase -> substrate	HPRD
160	CSK21_HUMAN	MYF6_HUMAN	kinase -> substrate	Robert H Newman (2013)
161	ELK1_HUMAN	EGR2_HUMAN	TF -> target gene	TRANSFAC
162	AKT1_HUMAN	THA_HUMAN	kinase -> substrate	Robert H Newman (2013)
163	CSK21_HUMAN	EGR1_HUMAN	kinase -> substrate	HPRD
164	FOXO1_HUMAN	IBP1_HUMAN	TF -> target gene	TRANSFAC
165	AKT1_HUMAN	SOX9_HUMAN	kinase -> substrate	Robert H Newman (2013)
166	KS6A2_HUMAN	CSEN_HUMAN	kinase -> substrate	Robert H Newman (2013)
167	CDK4_HUMAN	FOXN2_HUMAN	kinase -> substrate	Robert H Newman (2013)
168	MK08_HUMAN	NFAC2_HUMAN	kinase -> substrate	KEGG
169	KS6A2_HUMAN	GABPA_HUMAN	kinase -> substrate	Robert H Newman (2013)
170	MK08_HUMAN	PAX2_HUMAN	kinase -> substrate	NetPath
171	CDK4_HUMAN	PKNX1_HUMAN	kinase -> substrate	Robert H Newman (2013)
172	MK08_HUMAN	DYR1B_HUMAN	kinase -> substrate	Robert H Newman (2013)
173	MK08_HUMAN	JUND_HUMAN	kinase -> substrate	KEGG
174	CDK1_HUMAN	CUX1_HUMAN	kinase -> substrate	RegPhos
175	CDK1_HUMAN	CDK7_HUMAN	kinase -> substrate	RegPhos
176	CDK5_HUMAN	MEF2D_HUMAN	kinase -> substrate	RegPhos
177	MK07_HUMAN	MEF2D_HUMAN	kinase -> substrate	HPRD
178	CDK1_HUMAN	HMGA2_HUMAN	kinase -> substrate	RegPhos
179	NFAC2_HUMAN	EGR3_HUMAN	TF -> target gene	TRANSFAC
180	DYR1B_HUMAN	HNF1A_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
181	CDK7_HUMAN	PO2F1_HUMAN	kinase -> substrate	RegPhos; Robert H Newman (2013)
182	BMR1A_HUMAN	SYSC_HUMAN	kinase -> substrate	Robert H Newman (2013)
183	BMR1A_HUMAN	SMAD1_HUMAN	kinase -> substrate	KEGG
184	BMR1A_HUMAN	AIRE_HUMAN	kinase -> substrate	Robert H Newman (2013)
185	BMR1A_HUMAN	RUVB1_HUMAN	kinase -> substrate	Robert H Newman (2013)
186	BMR1A_HUMAN	SRXN1_HUMAN	kinase -> substrate	Robert H Newman (2013)
187	BMR1A_HUMAN	HCLS1_HUMAN	kinase -> substrate	Robert H Newman (2013)
188	BMR1A_HUMAN	BPL1_HUMAN	kinase -> substrate	Robert H Newman (2013)
189	BMR1A_HUMAN	CSRP3_HUMAN	kinase -> substrate	Robert H Newman (2013)
190	BMR1A_HUMAN	IF2A_HUMAN	kinase -> substrate	Robert H Newman (2013)
191	BMR1A_HUMAN	KAPCB_HUMAN	kinase -> substrate	Robert H Newman (2013)
192	BMR1A_HUMAN	NDF1_HUMAN	kinase -> substrate	Robert H Newman (2013)
193	BMR1A_HUMAN	ASAP3_HUMAN	kinase -> substrate	Robert H Newman (2013)

⁺Protein attribute:

protein with cancer-related variations (CanProVar)

up expressed protein;

down expressed protein(dbDEPC)

protein with hyperphosphorylation site (PhosphoSitePlus)

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network