Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GNAI3_HUMAN
Description:guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 [Source:HGNC Symbol;Acc:4387]
Location:chr1 p13.3
Node attribute:Gprotein

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y354KECGLy_____PhosphoSitePlus
Y320DTKEIyTHFTCG-alphaPhosphoSitePlus
Y167ISQSNyIPTQQG-alphaPhosphoSitePlus
Y61IHEDGySEDECG-alphaPhosphoSitePlus
S62HEDGYsEDECKG-alphaPhosphoSitePlus
Y69DECKQyKVVVYG-alphaPhosphoSitePlus
Y69DECKQyKVVVYHPRD; phosphoELM

Dephosphorylation site
GNAI3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000358867I78VCOSMICHead and Neck Cancer21798893

Differential expressed protein
GNAI3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
GNAI3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
5HT5A_HUMANGNAI3_HUMANGPCR -> GproteingpDB
HRH4_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PSYR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PAR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
OGR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
OPRM_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GPR63_HUMANGNAI3_HUMANGPCR -> GproteingpDB
FZD1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
NPY2R_HUMANGNAI3_HUMANGPCR -> GproteingpDB
OPRK_HUMANGNAI3_HUMANGPCR -> GproteingpDB
OXYR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CXCR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR10_HUMANGNAI3_HUMANGPCR -> GproteingpDB
NPY4R_HUMANGNAI3_HUMANGPCR -> GproteingpDB
5HT1A_HUMANGNAI3_HUMANGPCR -> GproteingpDB
FSHR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
RL3R2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
LSHR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
SSR4_HUMANGNAI3_HUMANGPCR -> GproteingpDB
LT4R2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
HCAR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CNR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
LPAR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GPR17_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GRM4_HUMANGNAI3_HUMANGPCR -> GproteingpDB
S1PR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
S1PR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
HCAR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GRM8_HUMANGNAI3_HUMANGPCR -> GproteingpDB
LT4R1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PD2R2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
AA1R_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GABR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
S1PR5_HUMANGNAI3_HUMANGPCR -> GproteingpDB
HRH3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CXCR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CASR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
AA3R_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR6_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR5_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PTAFR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PAR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ADA2A_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GRM3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CXCR6_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PE2R3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CXCR5_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ADA2B_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ACM2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GPR12_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GALR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
5HT1B_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR4_HUMANGNAI3_HUMANGPCR -> GproteingpDB
FPR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
MTR1A_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GPR6_HUMANGNAI3_HUMANGPCR -> GproteingpDB
SSR5_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCBP2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ADRB3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR8_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GRM2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PAR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ADA2C_HUMANGNAI3_HUMANGPCR -> GproteingpDB
PAR4_HUMANGNAI3_HUMANGPCR -> GproteingpDB
LPAR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
DRD3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ACM4_HUMANGNAI3_HUMANGPCR -> GproteingpDB
OPRX_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CXCR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GRM7_HUMANGNAI3_HUMANGPCR -> GproteingpDB
DRD2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR9_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GABR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CXCR4_HUMANGNAI3_HUMANGPCR -> GproteingpDB
RL3R1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
EDNRB_HUMANGNAI3_HUMANGPCR -> GproteingpDB
SSR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
AGTR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
NPY5R_HUMANGNAI3_HUMANGPCR -> GproteingpDB
OXER1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
5HT1E_HUMANGNAI3_HUMANGPCR -> GproteingpDB
SSR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
LPAR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB
C3AR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
P2Y12_HUMANGNAI3_HUMANGPCR -> GproteingpDB
CCR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
AGTR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB
MCHR1_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GP132_HUMANGNAI3_HUMANGPCR -> GproteingpDB
GNAI3_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAI3_HUMANIRK5_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBA3E_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB2B_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB4B_HUMANGprotein -> effectorgpDB
GNAI3_HUMANADCY1_HUMANGprotein -> effectorgpDB
GNAI3_HUMANGRIN1_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB1_HUMANGprotein -> effectorgpDB
GNAI3_HUMANRAC1_HUMANGprotein -> effectorgpDB
GNAI3_HUMANADCY6_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBG1_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBA3C_HUMANGprotein -> effectorgpDB
GNAI3_HUMANIRK9_HUMANGprotein -> effectorgpDB
GNAI3_HUMANGRIN2_HUMANGprotein -> effectorgpDB
GNAI3_HUMANIRK6_HUMANGprotein -> effectorgpDB
GNAI3_HUMANIRK3_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBA8_HUMANGprotein -> effectorgpDB
GNAI3_HUMANRAC2_HUMANGprotein -> effectorgpDB
GNAI3_HUMANSRC_HUMANGprotein -> effectorgpDB
GNAI3_HUMANRAC3_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBG2_HUMANGprotein -> effectorgpDB
GNAI3_HUMANADCY5_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBA1C_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB5_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBA4B_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB6_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB3_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBA4A_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBE_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBD_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB4A_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBA1A_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBAL3_HUMANGprotein -> effectorgpDB
GNAI3_HUMANCSK_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB8_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBA1B_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04730Long-term depression
hsa04726Serotonergic synapse
hsa04360Axon guidance
hsa04723Retrograde endocannabinoid signaling
hsa04670Leukocyte transendothelial migration
hsa04724Glutamatergic synapse
hsa04916Melanogenesis
hsa04971Gastric acid secretion
hsa04725Cholinergic synapse
hsa05133Pertussis
hsa05030Cocaine addiction
hsa04727GABAergic synapse
hsa04530Tight junction
hsa05032Morphine addiction
hsa05034Alcoholism
hsa04540Gap junction
hsa04062Chemokine signaling pathway
hsa04914Progesterone-mediated oocyte maturation
hsa05145Toxoplasmosis
hsa04728Dopaminergic synapse
hsa05142Chagas disease (American trypanosomiasis)

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004871signal transducer activityIBAmolecular_function
GO:0042588zymogen granuleIEAcellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0007165signal transductionIEAbiological_process
GO:0007194negative regulation of adenylate cyclase activityTASbiological_process
GO:0005525GTP bindingIEAmolecular_function
GO:0005834heterotrimeric G-protein complexIBAcellular_component
GO:0006184GTP catabolic processIBAbiological_process
GO:0016020membraneIEAcellular_component
GO:0031683G-protein beta/gamma-subunit complex bindingIBAmolecular_function
GO:0005813centrosomeIDAcellular_component
GO:0007193adenylate cyclase-inhibiting G-protein coupled recTASbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0031821G-protein coupled serotonin receptor bindingIEAmolecular_function
GO:0030168platelet activationTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0006906vesicle fusionIEAbiological_process
GO:0007049cell cycleIEAbiological_process
GO:0019001guanyl nucleotide bindingIEAmolecular_function
GO:0007596blood coagulationTASbiological_process
GO:0007268synaptic transmissionTASbiological_process
GO:0006810transportNASbiological_process
GO:0051301cell divisionIDAbiological_process
GO:0003924GTPase activityIBAmolecular_function
GO:0030496midbodyIDAcellular_component
GO:0045121membrane raftIEAcellular_component
GO:0031234extrinsic to internal side of plasma membraneIBAcellular_component


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