Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ADA2B_HUMAN
Description:adrenoceptor alpha 2B [Source:HGNC Symbol;Acc:282]
Location:chr2 q11.1
Node attribute:receptor; GPCR

Phosphorylation site
ADA2B_HUMAN do not have phosphorylation site.

Dephosphorylation site
ADA2B_HUMAN do not have dephosphorylation site.

Mutation site
ADA2B_HUMAN do not have mutation site.

Differential expressed protein
ADA2B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ADA2B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DOPO_HUMANADA2B_HUMANligand -> receptorHPMR
ADA2B_HUMANGNAI2_HUMANGPCR -> GproteingpDB
ADA2B_HUMANGNAI3_HUMANGPCR -> GproteingpDB
ADA2B_HUMANGNAI1_HUMANGPCR -> GproteingpDB
ADA2B_HUMANGNAO_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051379epinephrine bindingIDAmolecular_function
GO:0004938alpha2-adrenergic receptor activityIDAmolecular_function
GO:0045777positive regulation of blood pressureIEAbiological_process
GO:0001525angiogenesisIEAbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0010700negative regulation of norepinephrine secretionNASbiological_process
GO:0032148activation of protein kinase B activityIDAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0000165MAPK cascadeIEAbiological_process
GO:0070474positive regulation of uterine smooth muscle contrIEAbiological_process
GO:0035625epidermal growth factor-activated receptor transacIDAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0045666positive regulation of neuron differentiationIDAbiological_process
GO:0000187activation of MAPK activityIEAbiological_process
GO:0030168platelet activationTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0071883activation of MAPK activity by adrenergic receptorIDAbiological_process
GO:0007565female pregnancyIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0032811negative regulation of epinephrine secretionNASbiological_process
GO:0004938alpha2-adrenergic receptor activityIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0003056regulation of vascular smooth muscle contractionIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0004935adrenergic receptor activityIEAmolecular_function