Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AA3R_HUMAN
Description:adenosine A3 receptor [Source:HGNC Symbol;Acc:268]
Location:chr1 p13.2
Node attribute:GPCR

Phosphorylation site
AA3R_HUMAN do not have phosphorylation site.

Dephosphorylation site
AA3R_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000241356A105THPIColorectal Cancer16959974
ENSP00000358730A105TSjoblom2006Intestines Cancer16959974
ENSP00000241356F80YCOSMICOvarian Cancer21720365
ENSP00000358730R111WBIOMARTBreast Cancer21930507, 21930502
ENSP00000241356R111WBIOMARTBreast Cancer21930507, 21930502
ENSP00000241356A299TBIOMARTBreast Cancer21930507, 21930502
ENSP00000358730G190VBIOMARTBreast Cancer21930507, 21930502
ENSP00000241356M174ICOSMICOvarian Cancer21720365
ENSP00000241356A105TSjoblom2006, COSMICIntestines Cancer16959974

Differential expressed protein
AA3R_HUMAN is not differential expressed protein.

Hyperphosphorylation site
AA3R_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AA3R_HUMANGNAI1_HUMANGPCR -> GproteingpDB
AA3R_HUMANGNAI3_HUMANGPCR -> GproteingpDB
AA3R_HUMANGNAO_HUMANGPCR -> GproteingpDB
AA3R_HUMANGNAI2_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0050850positive regulation of calcium-mediated signalingIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0001973adenosine receptor signaling pathwayIEAbiological_process
GO:0001609G-protein coupled adenosine receptor activityIEAmolecular_function
GO:0007190activation of adenylate cyclase activityTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0007165signal transductionTASbiological_process
GO:0050729positive regulation of inflammatory responseIEAbiological_process
GO:0009611response to woundingTASbiological_process
GO:0070257positive regulation of mucus secretionIEAbiological_process
GO:0008016regulation of heart contractionTASbiological_process
GO:0005887integral to plasma membraneIEAcellular_component
GO:0014068positive regulation of phosphatidylinositol 3-kinaIEAbiological_process
GO:0006954inflammatory responseTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0043306positive regulation of mast cell degranulationIEAbiological_process
GO:0002687positive regulation of leukocyte migrationIEAbiological_process
GO:0002553histamine secretion by mast cellIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component


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