| UniProt/SwissProt ID: | LPAR2_HUMAN |
| Description: | lysophosphatidic acid receptor 2 [Source:HGNC Symbol;Acc:3168] |
| Location: | chr19 p13.11 |
| Node attribute: | receptor; GPCR |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y325 | RESVHyTSSAQ | PhosphoSitePlus | |
| Y295 | VNAAVySCRDA | 7tm_1; TM | PhosphoSitePlus |
| Dephosphorylation site |
| LPAR2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| LPAR2_HUMAN do not have mutation site. |
| Differential expressed protein |
| LPAR2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| LPAR2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| LIPH_HUMAN | LPAR2_HUMAN | ligand -> receptor | HPMR |
| LPAR2_HUMAN | GNAI2_HUMAN | GPCR -> Gprotein | gpDB |
| LPAR2_HUMAN | GNA13_HUMAN | GPCR -> Gprotein | gpDB |
| LPAR2_HUMAN | GNAQ_HUMAN | GPCR -> Gprotein | gpDB |
| LPAR2_HUMAN | GNAI1_HUMAN | GPCR -> Gprotein | gpDB |
| LPAR2_HUMAN | GNAI3_HUMAN | GPCR -> Gprotein | gpDB |
| LPAR2_HUMAN | GNA11_HUMAN | GPCR -> Gprotein | gpDB |
| LPAR2_HUMAN | GNAO_HUMAN | GPCR -> Gprotein | gpDB |
| LPAR2_HUMAN | GNA12_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0070915 | lysophosphatidic acid receptor activity | IEA | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0035025 | positive regulation of Rho protein signal transduc | IEA | biological_process |
| GO:0007204 | elevation of cytosolic calcium ion concentration | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0009986 | cell surface | IDA | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0030139 | endocytic vesicle | IDA | cellular_component |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0000187 | activation of MAPK activity | IEA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0008289 | lipid binding | TAS | molecular_function |
| GO:0043410 | positive regulation of MAPK cascade | IEA | biological_process |
| GO:0007202 | activation of phospholipase C activity | TAS | biological_process |