Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SSR3_HUMAN
Description:somatostatin receptor 3 [Source:HGNC Symbol;Acc:11332]
Location:chr22 q13.1
Node attribute:receptor; GPCR

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T348GPPEKtEEEDEHPRD
Y142MSVDRyLAVVH7tm_1PhosphoSitePlus
T341RSQEPtVGPPEPhosphoSitePlus
S332VLLRPsRRVRSPhosphoSitePlus; HPRD
S337SRRVRsQEPTVPhosphoSitePlus; HPRD
Y303VVALPyANSCA7tm_1; TMPhosphoSitePlus

Dephosphorylation site
SSR3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000330138P289HCOSMICLung Cancer20668451
ENSP00000330138R333HBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
SSR3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SSR3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CORT_HUMANSSR3_HUMANligand -> receptorHPMR
SMS_HUMANSSR3_HUMANligand -> receptorHPMR
SSR3_HUMANGNAO_HUMANGPCR -> GproteingpDB
SSR3_HUMANGNAI2_HUMANGPCR -> GproteingpDB
SSR3_HUMANGNAI1_HUMANGPCR -> GproteingpDB
SSR3_HUMANGNAI3_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0071392cellular response to estradiol stimulusIEAbiological_process
GO:0031513nonmotile primary ciliumISScellular_component
GO:0007187G-protein coupled receptor signaling pathway, coupTASbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0008285negative regulation of cell proliferationTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0030900forebrain developmentIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0021549cerebellum developmentIEAbiological_process
GO:0008628hormone-mediated apoptotic signaling pathwayTASbiological_process
GO:0004994somatostatin receptor activityIEAmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0038170somatostatin signaling pathwayTASbiological_process
GO:0031513nonmotile primary ciliumIEAcellular_component
GO:0042594response to starvationIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0007283spermatogenesisIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0016021integral to membraneIEAcellular_component
GO:0071385cellular response to glucocorticoid stimulusIEAbiological_process


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