Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MTR1A_HUMAN
Description:melatonin receptor 1A [Source:HGNC Symbol;Acc:7463]
Location:chr4 q35.2
Node attribute:GPCR; receptor; PPI(target)

Phosphorylation site
MTR1A_HUMAN do not have phosphorylation site.

Dephosphorylation site
MTR1A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000302811F196LCOSMICOvarian Cancer21720365
ENSP00000302811V327MCOSMICCentral Nervous System Neoplasms21163964

Differential expressed protein
MTR1A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MTR1A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SNAT_HUMANMTR1A_HUMANligand -> receptorHPMR
MTR1A_HUMANGNAI2_HUMANGPCR -> GproteingpDB
MTR1A_HUMANGNAI3_HUMANGPCR -> GproteingpDB
MTR1A_HUMANGNAO_HUMANGPCR -> GproteingpDB
MTR1A_HUMANGNAI1_HUMANGPCR -> GproteingpDB
GLHA_HUMANMTR1A_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007623circadian rhythmTASbiological_process
GO:0005887integral to plasma membraneIDAcellular_component
GO:0043235receptor complexIDAcellular_component
GO:0007617mating behaviorTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0097159organic cyclic compound bindingIPImolecular_function
GO:0042562hormone bindingIPImolecular_function
GO:0008502melatonin receptor activityIEAmolecular_function
GO:0007187G-protein coupled receptor signaling pathway, coupTASbiological_process
GO:0030828positive regulation of cGMP biosynthetic processIDAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0016021integral to membraneIEAcellular_component


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