Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TBB2A_HUMAN
Description:tubulin, beta 2A class IIa [Source:HGNC Symbol;Acc:12412]
Location:chr6 p25.2
Node attribute:effector

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y36DPTGSyHGDSDTubulinPhosphoSitePlus
T107AKGHYtEGAELTubulinPhosphoSitePlus
T218RTLKLtTPTYGTubulinPhosphoSitePlus
T219TLKLTtPTYGDTubulinPhosphoSitePlus
Y222LTTPTyGDLNHTubulinPhosphoSitePlus
S115AELVDsVLDVVTubulinPhosphoSitePlus
T274GFAPLtSRGSQTubulin_CPhosphoSitePlus
S322FRGRMsMKEVDTubulin_CPhosphoSitePlus
Y281RGSQQyRALTVTubulin_CPhosphoSitePlus
Y340NKNSSyFVEWITubulin_CPhosphoSitePlus
S382LFKRIsEQFTATubulin_CPhosphoSitePlus
S230LNHLVsATMSGPhosphoSitePlus
Y50ERINVyYNEAATubulinPhosphoSitePlus
T366LKMSAtFIGNSTubulin_CPhosphoSitePlus
Y106WAKGHyTEGAETubulinPhosphoSitePlus
S278LTSRGsQQYRATubulin_CPhosphoSitePlus
T221KLTTPtYGDLNTubulinPhosphoSitePlus
S338VQNKNsSYFVETubulin_CPhosphoSitePlus
S275FAPLTsRGSQQTTBK1HPRD
S75PGTMDsVRSGPTubulinPhosphoSitePlus
S339QNKNSsYFVEWTubulin_CPhosphoSitePlus
Y159KIREEyPDRIMTubulinPhosphoSitePlus
S78MDSVRsGPFGQTubulinPhosphoSitePlus
Y183TVVEPyNATLSTubulinPhosphoSitePlus
S275FAPLTsRGSQQTubulin_CPhosphoSitePlus
S95FVFGQsGAGNNTubulinPhosphoSitePlus
Y208DNEALyDICFRTubulinPhosphoSitePlus
T290TVPELtQQMFDTubulin_CPhosphoSitePlus

Dephosphorylation site
TBB2A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000369703R62WHPIColorectal Cancer16959974

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000369703Non-small cell lung carcinomaTreatment (none vs CIGB-300 treatment)cell lineUp2.520804217

Hyperphosphorylation site
TBB2A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GBG3_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBG8_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBG12_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBG11_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAI3_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAI1_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBG2_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAQ_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAO_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBB3_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBG10_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBG13_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBB2_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBG5_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAI2_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBB1_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBB5_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAS1_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GNAS2_HUMANTBB2A_HUMANGprotein -> effectorgpDB
GBG1_HUMANTBB2A_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04540Gap junction
hsa05130Pathogenic Escherichia coli infection
hsa04145Phagosome

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006184GTP catabolic processIEAbiological_process
GO:0051258protein polymerizationIEAbiological_process
GO:0005525GTP bindingIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0005198structural molecule activityIEAmolecular_function
GO:0006457protein foldingTASbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0007018microtubule-based movementIEAbiological_process
GO:0003924GTPase activityIEAmolecular_function
GO:0015630microtubule cytoskeletonIDAcellular_component
GO:0005874microtubuleIDAcellular_component
GO:0051084'de novo' posttranslational protein foldingTASbiological_process
GO:0043234protein complexIEAcellular_component
GO:0044267cellular protein metabolic processTASbiological_process


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