Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:5HT1B_HUMAN
Description:5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled [Source:HGNC Symbol;Acc:5287]
Location:chr6 q14.1
Node attribute:receptor; GPCR

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T60LLALItLATTLTMPhosphoSitePlus

Dephosphorylation site
5HT1B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000358963R188HCOSMICHead and Neck Cancer21798893
ENSP00000358963L304ICOSMICHead and Neck Cancer21798893

Differential expressed protein
5HT1B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
5HT1B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TPH1_HUMAN5HT1B_HUMANligand -> receptorHPMR
5HT1B_HUMANGNAO_HUMANGPCR -> GproteingpDB
5HT1B_HUMANGNAI2_HUMANGPCR -> GproteingpDB
5HT1B_HUMANGNAI3_HUMANGPCR -> GproteingpDB
5HT1B_HUMANGNAI1_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04726Serotonergic synapse
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042756drinking behaviorIEAbiological_process
GO:0051385response to mineralocorticoid stimulusIEAbiological_process
GO:0051967negative regulation of synaptic transmission, glutIEAbiological_process
GO:0046849bone remodelingIEAbiological_process
GO:0030818negative regulation of cAMP biosynthetic processIDAbiological_process
GO:0007268synaptic transmissionIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0051378serotonin bindingIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0071502cellular response to temperature stimulusIEAbiological_process
GO:0045471response to ethanolIEAbiological_process
GO:0002031G-protein coupled receptor internalizationIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0042220response to cocaineIEAbiological_process
GO:0004993serotonin receptor activityIEAmolecular_function
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0007210serotonin receptor signaling pathwayIEAbiological_process
GO:0008144drug bindingIEAmolecular_function
GO:0014059regulation of dopamine secretionIEAbiological_process
GO:0007205protein kinase C-activating G-protein coupled receIEAbiological_process
GO:0007631feeding behaviorIEAbiological_process
GO:0032229negative regulation of synaptic transmission, GABAIEAbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupTASbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0005886plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process


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