| UniProt/SwissProt ID: | GRIN1_HUMAN |
| Description: | G protein regulated inducer of neurite outgrowth 1 [Source:HGNC Symbol;Acc:24835] |
| Location: | chr5 q35.2 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S776 | AGAERsPCPEA | PhosphoSitePlus | |
| S850 | APRAPsPPSRR | PhosphoSitePlus; HPRD; phosphoELM | |
| S540 | AAPTAsGKAEP | PhosphoSitePlus | |
| T873 | TRSVAtGPMTP | PhosphoSitePlus | |
| S608 | EGKVGsLPLEK | PhosphoSitePlus | |
| T877 | ATGPMtPQAAA | PhosphoSitePlus | |
| S634 | KAQPQsGGKAE | PhosphoSitePlus | |
| S436 | KPELLsPGQAE | PhosphoSitePlus | |
| T450 | VGKAGtVSPGK | PhosphoSitePlus | |
| S73 | ESRHRsPSGAG | PhosphoSitePlus | |
| T313 | ASTGKtEPGLL | PhosphoSitePlus | |
| S744 | EGARGsEGRVE | PhosphoSitePlus | |
| S615 | PLEKGsPVTTT | PhosphoSitePlus | |
| T60 | APPRHtPDQSP | PhosphoSitePlus | |
| S577 | IGKVVsTPGKT | PhosphoSitePlus | |
| S862 | AGLQVsLGAAE | PhosphoSitePlus | |
| T618 | KGSPVtTTKAD | PhosphoSitePlus | |
| T336 | PVSSGtGAPGS | PhosphoSitePlus | |
| S64 | HTPDQsPGMES | PhosphoSitePlus | |
| S853 | APSPPsRRDAG | PhosphoSitePlus; HPRD; phosphoELM | |
| S452 | KAGTVsPGKED | PhosphoSitePlus | |
| S895 | RVRPGsALAAA | PhosphoSitePlus | |
| S341 | TGAPGsLGRLD | PhosphoSitePlus | |
| T973 | SGSVRtAPPDG | PhosphoSitePlus | |
| S914 | PVRDVsWDEKG | PhosphoSitePlus | |
| S491 | KTNPVsSGPGD | PhosphoSitePlus | |
| T515 | KAEPAtGGKGD | PhosphoSitePlus | |
| S75 | RHRSPsGAGEG | PhosphoSitePlus; HPRD; phosphoELM | |
| S334 | NGPVSsGTGAP | PhosphoSitePlus | |
| Dephosphorylation site |
| GRIN1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000305839 | G549C | COSMIC | Ovarian Cancer | 21720365 | ENSP00000305839 | G86S | COSMIC | Head and Neck Cancer | 21984974 |
| Differential expressed protein |
| GRIN1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| GRIN1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GNAI3_HUMAN | GRIN1_HUMAN | Gprotein -> effector | gpDB |
| GNAO_HUMAN | GRIN1_HUMAN | Gprotein -> effector | gpDB |
| GNAI1_HUMAN | GRIN1_HUMAN | Gprotein -> effector | gpDB |
| GNAI2_HUMAN | GRIN1_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| GRIN1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0030426 | growth cone | IEA | cellular_component |
| GO:0031175 | neuron projection development | IEA | biological_process |
| GO:0051219 | phosphoprotein binding | IEA | molecular_function |