| UniProt/SwissProt ID: | LT4R2_HUMAN |
| Description: | leukotriene B4 receptor 2 [Source:HGNC Symbol;Acc:19260] |
| Location: | chr14 q12 |
| Node attribute: | GPCR |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T355 | RSREGtMELRT | PhosphoSitePlus | |
| Y129 | GCKAVyYVCAL | TM; 7tm_1 | PhosphoSitePlus |
| T336 | GPRFLtRLFEG | PhosphoSitePlus | |
| Dephosphorylation site |
| LT4R2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| LT4R2_HUMAN do not have mutation site. |
| Differential expressed protein |
| LT4R2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| LT4R2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| LT4R2_HUMAN | GNAI3_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R2_HUMAN | GNAI1_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R2_HUMAN | GNA11_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R2_HUMAN | GNAI2_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R2_HUMAN | GNAO_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R2_HUMAN | GNAQ_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04020 | Calcium signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0001632 | leukotriene B4 receptor activity | IEA | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0006935 | chemotaxis | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0004974 | leukotriene receptor activity | IEA | molecular_function |
| GO:0007194 | negative regulation of adenylate cyclase activity | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0051546 | keratinocyte migration | IEA | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |