| UniProt/SwissProt ID: | OPRX_HUMAN |
| Description: | opiate receptor-like 1 [Source:HGNC Symbol;Acc:8155] |
| Location: | chr20 q13.33 |
| Node attribute: | receptor; GPCR |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S363 | LACKTsETVPR | PhosphoSitePlus | |
| Dephosphorylation site |
| OPRX_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000336764 | H29Y | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| OPRX_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| OPRX_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PNOC_HUMAN | OPRX_HUMAN | ligand -> receptor | HPMR |
| OPRX_HUMAN | GNAI2_HUMAN | GPCR -> Gprotein | gpDB |
| OPRX_HUMAN | GNAI1_HUMAN | GPCR -> Gprotein | gpDB |
| OPRX_HUMAN | GNAI3_HUMAN | GPCR -> Gprotein | gpDB |
| OPRX_HUMAN | GNAO_HUMAN | GPCR -> Gprotein | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0001626 | nociceptin receptor activity | IEA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007193 | adenylate cyclase-inhibiting G-protein coupled rec | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007204 | elevation of cytosolic calcium ion concentration | IGI | biological_process |
| GO:0007600 | sensory perception | TAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IGI | molecular_function |