Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SSR2_HUMAN
Description:somatostatin receptor 2 [Source:HGNC Symbol;Acc:11331]
Location:chr17 q25.1
Node attribute:receptor; GPCR

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T354RLNETtETQRTPhosphoSitePlus
Y71YVILRyAKMKT7tm_1PhosphoSitePlus
S343GERSDsKQDKSPhosphoSitePlus
T353SRLNEtTETQRPhosphoSitePlus
S341DDGERsDSKQDPhosphoSitePlus
S137CLTVMsIDRYLTM; 7tm_1PhosphoSitePlus

Dephosphorylation site
SSR2_HUMAN do not have dephosphorylation site.

Mutation site
SSR2_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000350198Testicular CancerNormal vs. Cancercell lineDown18489135

Hyperphosphorylation site
SSR2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SMS_HUMANSSR2_HUMANligand -> receptorHPMR
CORT_HUMANSSR2_HUMANligand -> receptorHPMR
SSR2_HUMANGNAI2_HUMANGPCR -> GproteingpDB
SSR2_HUMANGNAO_HUMANGPCR -> GproteingpDB
SSR2_HUMANGNAI1_HUMANGPCR -> GproteingpDB
SSR2_HUMANGNAI3_HUMANGPCR -> GproteingpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04971Gastric acid secretion
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0071385cellular response to glucocorticoid stimulusIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0006937regulation of muscle contractionIEAbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0008285negative regulation of cell proliferationTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0030165PDZ domain bindingIEAmolecular_function
GO:0038170somatostatin signaling pathwayIEAbiological_process
GO:0021549cerebellum developmentIEAbiological_process
GO:0030432peristalsisIEAbiological_process
GO:0030900forebrain developmentIEAbiological_process
GO:0007218neuropeptide signaling pathwayIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0007193adenylate cyclase-inhibiting G-protein coupled recIEAbiological_process
GO:0042594response to starvationIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0007283spermatogenesisIEAbiological_process
GO:0007584response to nutrientTASbiological_process
GO:0016020membraneIEAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0004994somatostatin receptor activityIEAmolecular_function
GO:0030165PDZ domain bindingIPImolecular_function
GO:0071392cellular response to estradiol stimulusIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0007586digestionTASbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupTASbiological_process
GO:0005515protein bindingIPImolecular_function


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23