| UniProt/SwissProt ID: | LT4R1_HUMAN |
| Description: | leukotriene B4 receptor [Source:HGNC Symbol;Acc:6713] |
| Location: | chr14 q12 |
| Node attribute: | substrate; GPCR; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T315 | SEASStRRGGS | PhosphoSitePlus | |
| T308 | KLLEGtGSEAS | GRK6 | HPRD |
| T150 | SFLLAtPVLAY | TM; 7tm_1 | PhosphoSitePlus |
| T308 | KLLEGtGSEAS | GRK-6 | phosphoELM |
| T308 | KLLEGtGSEAS | GPRK6(GRK6 | RegPhos |
| S314 | GSEASsTRRGG | PhosphoSitePlus | |
| S310 | LEGTGsEASST | PhosphoSitePlus; HPRD | |
| S104 | VSMYAsVLLIT | TM; 7tm_1 | PhosphoSitePlus |
| S313 | TGSEAsSTRRG | PhosphoSitePlus | |
| T308 | KLLEGtGSEAS | PhosphoSitePlus | |
| T308 | KLLEGtGSEAS | GPRK6 | RegPhos |
| Dephosphorylation site |
| LT4R1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| LT4R1_HUMAN do not have mutation site. |
| Differential expressed protein |
| LT4R1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| LT4R1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| LT4R1_HUMAN | GNAO_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R1_HUMAN | GNAI1_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R1_HUMAN | GNAI3_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R1_HUMAN | GNAI2_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R1_HUMAN | GNA11_HUMAN | GPCR -> Gprotein | gpDB |
| LT4R1_HUMAN | GNAQ_HUMAN | GPCR -> Gprotein | gpDB |
| GRK6_HUMAN | LT4R1_HUMAN | kinase -> substrate | HPRD; RegPhos; Robert H Newman (2013) |
| GLHA_HUMAN | LT4R1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004974 | leukotriene receptor activity | IEA | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0006954 | inflammatory response | IEA | biological_process |
| GO:0006928 | cellular component movement | TAS | biological_process |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0006936 | muscle contraction | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0006955 | immune response | TAS | biological_process |
| GO:0007200 | phospholipase C-activating G-protein coupled recep | TAS | biological_process |
| GO:0000166 | nucleotide binding | TAS | molecular_function |
| GO:0001632 | leukotriene B4 receptor activity | IEA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0004974 | leukotriene receptor activity | TAS | molecular_function |