Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IRK5_HUMAN
Description:potassium inwardly-rectifying channel, subfamily J, member 5 [Source:HGNC Symbol;Acc:6266]
Location:chr11 q24.3
Node attribute:effector

Phosphorylation site
IRK5_HUMAN do not have phosphorylation site.

Dephosphorylation site
IRK5_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000339960L337FCOSMICSkin Cancer21984974
ENSP00000339960D266EBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
IRK5_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IRK5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GNAI2_HUMANIRK5_HUMANGprotein -> effectorgpDB
GNAI3_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG13_HUMANIRK5_HUMANGprotein -> effectorgpDB
GNAQ_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBB5_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG11_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG3_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG2_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBB3_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBB1_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG10_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG8_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG5_HUMANIRK5_HUMANGprotein -> effectorgpDB
GNAI1_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG12_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBG1_HUMANIRK5_HUMANGprotein -> effectorgpDB
GBB2_HUMANIRK5_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04728Dopaminergic synapse
hsa05032Morphine addiction
hsa04726Serotonergic synapse
hsa04723Retrograde endocannabinoid signaling

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007268synaptic transmissionTASbiological_process
GO:0005242inward rectifier potassium channel activityIDAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0006813potassium ion transportTASbiological_process
GO:0008076voltage-gated potassium channel complexTAScellular_component
GO:0005886plasma membraneTAScellular_component
GO:0015467G-protein activated inward rectifier potassium chaIEAmolecular_function


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