Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:C3AR_HUMAN
Description:complement component 3a receptor 1 [Source:HGNC Symbol;Acc:1319]
Location:chr12 p13.31
Node attribute:GPCR; receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S465EELTRsTHCPSPhosphoSitePlus
S470STHCPsNNVISPhosphoSitePlus
T466ELTRStHCPSNPhosphoSitePlus
T463FSEELtRSTHCPhosphoSitePlus
S459LEAAFsEELTRPhosphoSitePlus

Dephosphorylation site
C3AR_HUMAN do not have dephosphorylation site.

Mutation site
C3AR_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000302079acute lymphocytic leukemiaNormal vs. CancertissueUp19291297

Hyperphosphorylation site
C3AR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CO3_HUMANC3AR_HUMANligand -> receptorHPMR
C3AR_HUMANGNA12_HUMANGPCR -> GproteingpDB
C3AR_HUMANGNAO_HUMANGPCR -> GproteingpDB
C3AR_HUMANGNA13_HUMANGPCR -> GproteingpDB
C3AR_HUMANGNAI1_HUMANGPCR -> GproteingpDB
C3AR_HUMANGNAZ_HUMANGPCR -> GproteingpDB
C3AR_HUMANGNAI2_HUMANGPCR -> GproteingpDB
C3AR_HUMANGNAI3_HUMANGPCR -> GproteingpDB
IP3KA_HUMANC3AR_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05150Staphylococcus aureus infection
hsa04610Complement and coagulation cascades
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0010575positive regulation vascular endothelial growth faIEAbiological_process
GO:0004930G-protein coupled receptor activityIGImolecular_function
GO:0004943C3a anaphylatoxin receptor activityIEAmolecular_function
GO:0006935chemotaxisIEAbiological_process
GO:0008015blood circulationTASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0045766positive regulation of angiogenesisIEAbiological_process
GO:0006954inflammatory responseTASbiological_process
GO:0090023positive regulation of neutrophil chemotaxisIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0007204elevation of cytosolic calcium ion concentrationIGIbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0004876complement component C3a receptor activityTASmolecular_function
GO:0004435phosphatidylinositol phospholipase C activityTASmolecular_function
GO:0010759positive regulation of macrophage chemotaxisIEAbiological_process


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